mycophenolic acid-4019 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mycophenolic acid-4019 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADAM23 ADAM metallopeptidase domain 23
AKAP5 A kinase (PRKA) anchor protein 5
AKAP7 A kinase (PRKA) anchor protein 7
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPT4 angiopoietin 4
ANP32A-IT1 ANP32A intronic transcript 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C11ORF68 chromosome 11 open reading frame 68
C19ORF60 chromosome 19 open reading frame 60
C22ORF29 chromosome 22 open reading frame 29
CALHM2 calcium homeostasis modulator 2
CCDC132 coiled-coil domain containing 132
CDC25A cell division cycle 25A
CDK20 cyclin-dependent kinase 20
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMP1 cementum protein 1
CEP162 centrosomal protein 162kDa
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CRTC1 CREB regulated transcription coactivator 1
CST4 cystatin S
CTAGE5 CTAGE family, member 5
DLX5 distal-less homeobox 5
DST dystonin
DTX2 deltex 2, E3 ubiquitin ligase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DTX3 deltex 3, E3 ubiquitin ligase
EPOR erythropoietin receptor
FAM120C family with sequence similarity 120C
FAS Fas cell surface death receptor
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL3ST4 galactose-3-O-sulfotransferase 4
GAS2L1 growth arrest-specific 2 like 1
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD14 potassium channel tetramerization domain containing 14
KLHL4 kelch-like family member 4
LINC00115 long intergenic non-protein coding RNA 115
LOXL3 lysyl oxidase-like 3
MORC1 MORC family CW-type zinc finger 1
NRF1 nuclear respiratory factor 1
PALM paralemmin
PASK PAS domain containing serine/threonine kinase
PENK proenkephalin
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHTF2 putative homeodomain transcription factor 2
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCI protein kinase C, iota
PROSC proline synthetase co-transcribed homolog (bacterial)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RAG1 recombination activating gene 1
RFXAP regulatory factor X-associated protein
RGS16 regulator of G-protein signaling 16
RHO rhodopsin
RNF39 ring finger protein 39
RS1 retinoschisin 1
SAMD4A sterile alpha motif domain containing 4A
SAT1 spermidine/spermine N1-acetyltransferase 1
SAYSD1 SAYSVFN motif domain containing 1
SIRT4 sirtuin 4
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOS2 son of sevenless homolog 2 (Drosophila)
SP110 SP110 nuclear body protein
STAT2 signal transducer and activator of transcription 2, 113kDa
STK17A serine/threonine kinase 17a
TEX41 testis expressed 41 (non-protein coding)
TFCP2L1 transcription factor CP2-like 1
THBD thrombomodulin
TIAM2 T-cell lymphoma invasion and metastasis 2
TLE2 transducin-like enhancer of split 2
TMEM242 transmembrane protein 242
TMEM246 transmembrane protein 246
TNNT3 troponin T type 3 (skeletal, fast)
TP63 tumor protein p63
TREX1 three prime repair exonuclease 1
TRIM3 tripartite motif containing 3
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
XYLB xylulokinase homolog (H. influenzae)
ZBED1 zinc finger, BED-type containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF24 zinc finger protein 24

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALOX15B arachidonate 15-lipoxygenase, type B
ANKRD11 ankyrin repeat domain 11
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGAP22 Rho GTPase activating protein 22
ARMC7 armadillo repeat containing 7
ARRB2 arrestin, beta 2
AXIN1 axin 1
B9D2 B9 protein domain 2
BIN3 bridging integrator 3
BRD1 bromodomain containing 1
BST1 bone marrow stromal cell antigen 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAPN15 calpain 15
CCNO cyclin O
CHI3L2 chitinase 3-like 2
CLEC16A C-type lectin domain family 16, member A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDN dendrin
EPN1 epsin 1
ERO1LB ERO1-like beta (S. cerevisiae)
EYA4 EYA transcriptional coactivator and phosphatase 4
FAT4 FAT atypical cadherin 4
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAS8 growth arrest-specific 8
GBX2 gastrulation brain homeobox 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJA9 gap junction protein, alpha 9, 59kDa
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
H1F0 H1 histone family, member 0
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
IGLL1 immunoglobulin lambda-like polypeptide 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPKA inositol-trisphosphate 3-kinase A
KCTD5 potassium channel tetramerization domain containing 5
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMNB1 lamin B1
MMP3 matrix metallopeptidase 3
MTERF4 mitochondrial transcription termination factor 4
MYO1F myosin IF
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NLGN1 neuroligin 1
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIP prolactin-induced protein
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMM2 phosphomannomutase 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRSS8 protease, serine, 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QSER1 glutamine and serine rich 1
RAB33B RAB33B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RALGDS ral guanine nucleotide dissociation stimulator
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHOBTB2 Rho-related BTB domain containing 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUFY2 RUN and FYVE domain containing 2
S100A3 S100 calcium binding protein A3
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SGK2 serum/glucocorticoid regulated kinase 2
SLAMF7 SLAM family member 7
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
STIM1 stromal interaction molecule 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THRAP3 thyroid hormone receptor associated protein 3
TICAM1 toll-like receptor adaptor molecule 1
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
USP19 ubiquitin specific peptidase 19
WDR18 WD repeat domain 18
WFDC2 WAP four-disulfide core domain 2
ZC3H3 zinc finger CCCH-type containing 3
ZFP30 ZFP30 zinc finger protein
ZNF276 zinc finger protein 276
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747
ZXDB zinc finger, X-linked, duplicated B