musculoskeletal system benign neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An organ system benign neoplasm that is located_in the muscular and skeletal organs. (Human Disease Ontology, DOID_0060099)
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Genes

292 genes co-occuring with the disease musculoskeletal system benign neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.94266
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.35768
ERCC6 excision repair cross-complementation group 6 1.28435
PGR progesterone receptor 1.2656
CDC73 cell division cycle 73 1.20959
CALD1 caldesmon 1 1.19402
ZSCAN12 zinc finger and SCAN domain containing 12 1.06606
ESR1 estrogen receptor 1 1.02777
IVL involucrin 0.983057
BOD1 biorientation of chromosomes in cell division 1 0.953273
CHRAC1 chromatin accessibility complex 1 0.941196
LHFPL3 lipoma HMGIC fusion partner-like 3 0.888438
TRBC1 T cell receptor beta constant 1 0.872872
KDM7A lysine (K)-specific demethylase 7A 0.868777
USP6 ubiquitin specific peptidase 6 0.849126
GNAS GNAS complex locus 0.842982
DCAF5 DDB1 and CUL4 associated factor 5 0.823308
ORC5 origin recognition complex, subunit 5 0.804436
ZNF133 zinc finger protein 133 0.785984
BAG6 BCL2-associated athanogene 6 0.757786
CD34 CD34 molecule 0.74883
ODAM odontogenic, ameloblast asssociated 0.748424
HOXA10 homeobox A10 0.716425
HOXA11 homeobox A11 0.703938
MYOD1 myogenic differentiation 1 0.70233
PCP4 Purkinje cell protein 4 0.697109
ZNRF3 zinc and ring finger 3 0.664769
MYOG myogenin (myogenic factor 4) 0.643797
ENO2 enolase 2 (gamma, neuronal) 0.640251
MEA1 male-enhanced antigen 1 0.631598
ALPP alkaline phosphatase, placental 0.624927
KREMEN1 kringle containing transmembrane protein 1 0.604201
ALPPL2 alkaline phosphatase, placental-like 2 0.60342
ALPL alkaline phosphatase, liver/bone/kidney 0.60225
CCS copper chaperone for superoxide dismutase 0.572662
TUBA1C tubulin, alpha 1c 0.55945
BGLAP bone gamma-carboxyglutamate (gla) protein 0.548583
PCNA proliferating cell nuclear antigen 0.542379
MED12 mediator complex subunit 12 0.528835
PAEP progestagen-associated endometrial protein 0.51919
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.517649
SOX8 SRY (sex determining region Y)-box 8 0.501144
TP53 tumor protein p53 0.501144
JDP2 Jun dimerization protein 2 0.498085
HMGA2 high mobility group AT-hook 2 0.477151
STAC SH3 and cysteine rich domain 0.455601
PZP pregnancy-zone protein 0.439034
TUBB2A tubulin, beta 2A class IIa 0.439034
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.417644
CLEC2A C-type lectin domain family 2, member A 0.410909
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.409414
RHCG Rh family, C glycoprotein 0.406425
TUBB tubulin, beta class I 0.402318
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.401199
CD68 CD68 molecule 0.399707
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.396725
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.394863
GSTA3 glutathione S-transferase alpha 3 0.388909
GSTA2 glutathione S-transferase alpha 2 0.387423
GSTA4 glutathione S-transferase alpha 4 0.386308
DCN decorin 0.384822
GSTA1 glutathione S-transferase alpha 1 0.380739
NME1-NME2 NME1-NME2 readthrough 0.37555
AQP9 aquaporin 9 0.362239
MYF6 myogenic factor 6 (herculin) 0.357446
AQP7 aquaporin 7 0.346777
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.344207
ADCY1 adenylate cyclase 1 (brain) 0.341639
B3GAT1 beta-1,3-glucuronyltransferase 1 0.332121
DKKL1 dickkopf-like 1 0.32009
ABHD14A abhydrolase domain containing 14A 0.317909
IGF1 insulin-like growth factor 1 (somatomedin C) 0.317909
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.315366
NCAN neurocan 0.30631
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.305587
LEMD3 LEM domain containing 3 0.302337
TP63 tumor protein p63 0.301976
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.300533
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.298731
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.298731
LEP leptin 0.292975
ADM adrenomedullin 0.290462
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.288668
SNED1 sushi, nidogen and EGF-like domains 1 0.28831
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.287235
S100A1 S100 calcium binding protein A1 0.28616
LNPEP leucyl/cystinyl aminopeptidase 0.285086
IL6ST interleukin 6 signal transducer 0.275089
COL4A6 collagen, type IV, alpha 6 0.269043
PTGES prostaglandin E synthase 0.264431
HBA2 hemoglobin, alpha 2 0.263722
PDE4B phosphodiesterase 4B, cAMP-specific 0.261599
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.260538
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.258417
ULK1 unc-51 like autophagy activating kinase 1 0.254888
AKR1C1 aldo-keto reductase family 1, member C1 0.249608
ARSH arylsulfatase family, member H 0.245396
SDC1 syndecan 1 0.238403
FSCN1 fascin actin-bundling protein 1 0.237706
RHD Rh blood group, D antigen 0.235616
CYS1 cystin 1 0.232489
MYH11 myosin, heavy chain 11, smooth muscle 0.230409
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.22937
PDGFB platelet-derived growth factor beta polypeptide 0.228333
PTH parathyroid hormone 0.225917
CDKN2A cyclin-dependent kinase inhibitor 2A 0.224884
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.223853
OXT oxytocin/neurophysin I prepropeptide 0.221793
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.215314
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.214975
PFKM phosphofructokinase, muscle 0.210925
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.210253
F8 coagulation factor VIII, procoagulant component 0.209918
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.203275
AKR1C2 aldo-keto reductase family 1, member C2 0.202946
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.201308
ELL elongation factor RNA polymerase II 0.200656
MAGEA4 melanoma antigen family A4 0.198064
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.19742
PSG9 pregnancy specific beta-1-glycoprotein 9 0.195183
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.194232
ACOT13 acyl-CoA thioesterase 13 0.193285
THEM4 thioesterase superfamily member 4 0.192344
LEPR leptin receptor 0.187415
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.18472
SOX9 SRY (sex determining region Y)-box 9 0.18472
IGF2 insulin-like growth factor 2 0.182375
PAX3 paired box 3 0.178403
S100A2 S100 calcium binding protein A2 0.178126
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.177029
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.174093
MRI1 methylthioribose-1-phosphate isomerase 1 0.173832
ESR2 estrogen receptor 2 (ER beta) 0.172291
CRABP2 cellular retinoic acid binding protein 2 0.171785
CYGB cytoglobin 0.169812
ACOT7 acyl-CoA thioesterase 7 0.166768
LGALS1 lectin, galactoside-binding, soluble, 1 0.166095
HBD hemoglobin, delta 0.165655
AR androgen receptor 0.164149
EPO erythropoietin 0.164149
KRT20 keratin 20, type I 0.163317
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.162505
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.161331
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.160574
MCF2 MCF.2 cell line derived transforming sequence 0.160387
MYF5 myogenic factor 5 0.160387
ADRB2 adrenoceptor beta 2, surface 0.160387
GFER growth factor, augmenter of liver regeneration 0.159838
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.139181
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.138571
S100A9 S100 calcium binding protein A9 0.135544
KITLG KIT ligand 0.133565
RUNX2 runt-related transcription factor 2 0.132318
VIM vimentin 0.130571
JAG2 jagged 2 0.129653
APOF apolipoprotein F 0.129497
WWOX WW domain containing oxidoreductase 0.128911
S100A6 S100 calcium binding protein A6 0.12816
EWSR1 EWS RNA-binding protein 1 0.12801
SP7 Sp7 transcription factor 0.127832
CD2 CD2 molecule 0.127588
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.127312
MAPK14 mitogen-activated protein kinase 14 0.12685
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.126595
SYP synaptophysin 0.126417
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.1255
CD99 CD99 molecule 0.125251
IBSP integrin-binding sialoprotein 0.125221
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.125211
MN1 meningioma (disrupted in balanced translocation) 1 0.124857
ERN1 endoplasmic reticulum to nucleus signaling 1 0.1243
AXIN1 axin 1 0.123408
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 0.122619
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.121994
PGRMC1 progesterone receptor membrane component 1 0.12064
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.120101
S100A4 S100 calcium binding protein A4 0.119213
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.118981
HSPA8 heat shock 70kDa protein 8 0.118343
TES testin LIM domain protein 0.118216
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.117891
SPP1 secreted phosphoprotein 1 0.117104
PTER phosphotriesterase related 0.11573
MNT MAX network transcriptional repressor 0.115015
MEF2C myocyte enhancer factor 2C 0.114839
JAG1 jagged 1 0.114823
PTPRC protein tyrosine phosphatase, receptor type, C 0.114067
PTHLH parathyroid hormone-like hormone 0.113918
SP100 SP100 nuclear antigen 0.113019
CLDN1 claudin 1 0.112968
NID1 nidogen 1 0.112021
CLDN7 claudin 7 0.111696
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.111551
ATXN3 ataxin 3 0.111154
EZR ezrin 0.110561
NOTCH1 notch 1 0.110356
LCK LCK proto-oncogene, Src family tyrosine kinase 0.110114
CTSK cathepsin K 0.110114
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.110001
PAX7 paired box 7 0.109771
ERBB4 erb-b2 receptor tyrosine kinase 4 0.109771
AMELY amelogenin, Y-linked 0.108727
TFE3 transcription factor binding to IGHM enhancer 3 0.107188
AMELX amelogenin, X-linked 0.107066
DDIT3 DNA-damage-inducible transcript 3 0.106881
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.106798
AFP alpha-fetoprotein 0.106715
SOD2 superoxide dismutase 2, mitochondrial 0.10659
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.106465
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.106341
MAGEA1 melanoma antigen family A1 0.105414
MSTN myostatin 0.105136
MB myoglobin 0.10488
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.104642
NOVA2 neuro-oncological ventral antigen 2 0.104117
ACAN aggrecan 0.103942
MYB v-myb avian myeloblastosis viral oncogene homolog 0.103789
OXTR oxytocin receptor 0.103767
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.103679
EDN3 endothelin 3 0.103546
PYGB phosphorylase, glycogen; brain 0.103501
PYGL phosphorylase, glycogen, liver 0.103119
BAX BCL2-associated X protein 0.102626
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.102308
CTSS cathepsin S 0.102239
MKI67 marker of proliferation Ki-67 0.102032
CHGA chromogranin A 0.099185
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.097322
GAN gigaxonin 0.097246
AGO2 argonaute RISC catalytic component 2 0.096292
HBA1 hemoglobin, alpha 1 0.095781
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.09452
F3 coagulation factor III (thromboplastin, tissue factor) 0.094363
RUNX1 runt-related transcription factor 1 0.093736
MAP2 microtubule-associated protein 2 0.093181
FSCN3 fascin actin-bundling protein 3, testicular 0.092569
FSCN2 fascin actin-bundling protein 2, retinal 0.090681
F2 coagulation factor II (thrombin) 0.087792
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.087479
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.087479
DAPK1 death-associated protein kinase 1 0.086513
COL4A5 collagen, type IV, alpha 5 0.086428
ACTB actin, beta 0.085795
CTSD cathepsin D 0.08464
GFAP glial fibrillary acidic protein 0.084289
CCL11 chemokine (C-C motif) ligand 11 0.083909
ANXA1 annexin A1 0.083733
DNM2 dynamin 2 0.083704
THBS1 thrombospondin 1 0.0835
ACTG1 actin gamma 1 0.083471
CTSB cathepsin B 0.083383
SMAD3 SMAD family member 3 0.082526
S100B S100 calcium binding protein B 0.082053
PDLIM7 PDZ and LIM domain 7 (enigma) 0.081875
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.081846
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.081816
WT1 Wilms tumor 1 0.081159
NOTCH3 notch 3 0.07993
PROS1 protein S (alpha) 0.07866
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.078629
CDK2 cyclin-dependent kinase 2 0.077866
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.077805
NOTCH4 notch 4 0.077591
GIF gastric intrinsic factor (vitamin B synthesis) 0.077134
CCR3 chemokine (C-C motif) receptor 3 0.076396
CMA1 chymase 1, mast cell 0.075718
CDK4 cyclin-dependent kinase 4 0.074449
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.074169
AKR1C3 aldo-keto reductase family 1, member C3 0.073266
SMAD2 SMAD family member 2 0.073079
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.073048
PYGM phosphorylase, glycogen, muscle 0.073016
NCAM1 neural cell adhesion molecule 1 0.072923
LOR loricrin 0.072892
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.072829
AQP3 aquaporin 3 (Gill blood group) 0.072673
GNRHR gonadotropin-releasing hormone receptor 0.072299
CCL2 chemokine (C-C motif) ligand 2 0.071765
SHBG sex hormone-binding globulin 0.071703
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.071671
PRL prolactin 0.071545
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.071545
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.071451
CCL5 chemokine (C-C motif) ligand 5 0.071451
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.071451
KRT7 keratin 7, type II 0.071106
MMP13 matrix metallopeptidase 13 0.070604
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.070289
GPX3 glutathione peroxidase 3 0.070289
IL1A interleukin 1, alpha 0.070131
TLR9 toll-like receptor 9 0.069784
FXYD5 FXYD domain containing ion transport regulator 5 0.069752