muscle tissue disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:66
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Genes

269 genes associated with the disease muscle tissue disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
CETP cholesteryl ester transfer protein, plasma 0.483327
GCKR glucokinase (hexokinase 4) regulator 0.437555
AKAP13 A kinase (PRKA) anchor protein 13 0.43412
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.418237
BAG3 BCL2-associated athanogene 3 0.406304
SOX5 SRY (sex determining region Y)-box 5 0.38617
FADS2 fatty acid desaturase 2 0.374856
CHN2 chimerin 2 0.37243
TRHR thyrotropin-releasing hormone receptor 0.37196
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.371567
ZBTB17 zinc finger and BTB domain containing 17 0.364313
LPA lipoprotein, Lp(a) 0.364313
APOC1 apolipoprotein C-I 0.363079
TMEM258 transmembrane protein 258 0.361002
PCSK5 proprotein convertase subtilisin/kexin type 5 0.359537
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.358579
FHIT fragile histidine triad 0.354665
BUD13 BUD13 homolog (S. cerevisiae) 0.349065
RYR1 ryanodine receptor 1 (skeletal) 0.344196
COL17A1 collagen, type XVII, alpha 1 0.337331
CLMN calmin (calponin-like, transmembrane) 0.337331
GPN1 GPN-loop GTPase 1 0.332511
LPL lipoprotein lipase 0.330761
IFT172 intraflagellar transport 172 0.329507
HCG22 HLA complex group 22 0.329069
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.327206
ZNF512 zinc finger protein 512 0.327021
APOE apolipoprotein E 0.326661
ZPR1 ZPR1 zinc finger 0.32321
C2ORF16 chromosome 2 open reading frame 16 0.321937
ESRRG estrogen-related receptor gamma 0.320318
RUNX1 runt-related transcription factor 1 0.314549
LOC339975 uncharacterized LOC339975 0.312353
ASB18 ankyrin repeat and SOCS box containing 18 0.312353
ADD2 adducin 2 (beta) 0.312072
APOA5 apolipoprotein A-V 0.311798
LMNTD2 lamin tail domain containing 2 0.308824
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 0.308143
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.304659
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 0.301101
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0.29914
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.297767
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.296563
FGF1 fibroblast growth factor 1 (acidic) 0.294775
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.289391
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.286369
WWOX WW domain containing oxidoreductase 0.285611
CNKSR3 CNKSR family member 3 0.283528
TTC7A tetratricopeptide repeat domain 7A 0.282366
PRDM16 PR domain containing 16 0.282366
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.281662
ISPD isoprenoid synthase domain containing 0.279459
EXT1 exostosin glycosyltransferase 1 0.277651
PAIP2B poly(A) binding protein interacting protein 2B 0.277245
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.275412
ZNF204P zinc finger protein 204, pseudogene 0.273732
FADS1 fatty acid desaturase 1 0.273506
C12ORF40 chromosome 12 open reading frame 40 0.273373
RBMS3 RNA binding motif, single stranded interacting protein 3 0.273152
FBXL18 F-box and leucine-rich repeat protein 18 0.271774
ADGRB3 adhesion G protein-coupled receptor B3 0.271419
APOC1P1 apolipoprotein C-I pseudogene 1 0.271034
DYSF dysferlin 0.270659
PHF11 PHD finger protein 11 0.267953
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.265662
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.265425
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.265141
FNDC4 fibronectin type III domain containing 4 0.265141
PLCL1 phospholipase C-like 1 0.265141
CNTNAP5 contactin associated protein-like 5 0.265141
SCN11A sodium channel, voltage gated, type XI alpha subunit 0.264912
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.263678
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.260952
AKAP6 A kinase (PRKA) anchor protein 6 0.260933
GLIS1 GLIS family zinc finger 1 0.260741
TSPAN9 tetraspanin 9 0.260741
KRT82 keratin 82, type II 0.260218
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.259999
TDP2 tyrosyl-DNA phosphodiesterase 2 0.258953
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.257376
ARL15 ADP-ribosylation factor-like 15 0.2572
SHISA9 shisa family member 9 0.256343
LIPC lipase, hepatic 0.255528
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.255528
HOTTIP HOXA distal transcript antisense RNA 0.255528
IQCK IQ motif containing K 0.255528
MYRF myelin regulatory factor 0.255528
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.254153
ARMC2 armadillo repeat containing 2 0.254153
ANTXR1 anthrax toxin receptor 1 0.254007
ATXN1 ataxin 1 0.254007
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.252613
MLXIPL MLX interacting protein-like 0.252613
GRM3 glutamate receptor, metabotropic 3 0.252613
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 0.252613
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.252613
NCAM2 neural cell adhesion molecule 2 0.251829
DCPS decapping enzyme, scavenger 0.251327
ZNF513 zinc finger protein 513 0.251327
APOL3 apolipoprotein L, 3 0.251327
NRBP1 nuclear receptor binding protein 1 0.251327
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.251327
SNX17 sorting nexin 17 0.251327
KIF16B kinesin family member 16B 0.251327
MRC2 mannose receptor, C type 2 0.251327
NUDCD1 NudC domain containing 1 0.251203
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.250959
FBXL7 F-box and leucine-rich repeat protein 7 0.250132
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.250132
APCDD1L adenomatosis polyposis coli down-regulated 1-like 0.249126
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.249018
IGF1 insulin-like growth factor 1 (somatomedin C) 0.247974
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.246991
KIAA0319 KIAA0319 0.246991
COL13A1 collagen, type XIII, alpha 1 0.246991
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.246708
NRP1 neuropilin 1 0.246614
ZBBX zinc finger, B-box domain containing 0.245187
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.245187
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.245187
KAT2B K(lysine) acetyltransferase 2B 0.24356
SH3BP4 SH3-domain binding protein 4 0.242804
ELOVL5 ELOVL fatty acid elongase 5 0.242804
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.242804
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.242804
CALCR calcitonin receptor 0.241731
OFCC1 orofacial cleft 1 candidate 1 0.241662
KRT84 keratin 84, type II 0.241593
MICA MHC class I polypeptide-related sequence A 0.241389
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.240725
SETD5 SET domain containing 5 0.240725
FEN1 flap structure-specific endonuclease 1 0.240087
LRRC49 leucine rich repeat containing 49 0.240087
LDLR low density lipoprotein receptor 0.239473
VWC2L von Willebrand factor C domain containing protein 2-like 0.239115
RIMS1 regulating synaptic membrane exocytosis 1 0.23831
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.23831
ASTN2 astrotactin 2 0.23831
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.23831
ZNF618 zinc finger protein 618 0.237226
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.237226
SCARA3 scavenger receptor class A, member 3 0.236966
SLIT2 slit homolog 2 (Drosophila) 0.236812
MTMR2 myotubularin related protein 2 0.23671
CSMD2 CUB and Sushi multiple domains 2 0.236608
TASP1 taspase, threonine aspartase, 1 0.236558
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.23621
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.23621
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 0.235725
DPYD dihydropyrimidine dehydrogenase 0.235725
KHDC1L KH homology domain containing 1-like 0.235725
KDM4B lysine (K)-specific demethylase 4B 0.235725
SLC38A4 solute carrier family 38, member 4 0.235725
NXPH1 neurexophilin 1 0.235582
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.2353
CLNK cytokine-dependent hematopoietic cell linker 0.235254
DNAH9 dynein, axonemal, heavy chain 9 0.234978
OPCML opioid binding protein/cell adhesion molecule-like 0.234796
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.234796
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.234351
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.234351
TEAD3 TEA domain family member 3 0.233918
OTOGL otogelin-like 0.233918
ULK4 unc-51 like kinase 4 0.233497
SLC35F3 solute carrier family 35, member F3 0.232489
MCTP2 multiple C2 domains, transmembrane 2 0.23218
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.231914
MATN2 matrilin 2 0.231914
AMPD3 adenosine monophosphate deaminase 3 0.231914
DGKI diacylglycerol kinase, iota 0.231914
SEZ6L seizure related 6 homolog (mouse)-like 0.231578
GAB1 GRB2-associated binding protein 1 0.231541
LOC145845 uncharacterized LOC145845 0.231431
SOSTDC1 sclerostin domain containing 1 0.230822
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.230474
TPTE2P6 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 6 0.230474
C16ORF45 chromosome 16 open reading frame 45 0.230302
RHPN2 rhophilin, Rho GTPase binding protein 2 0.230133
THRB thyroid hormone receptor, beta 0.230133
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.230133
NELL1 NEL-like 1 (chicken) 0.230099
KPNA5 karyopherin alpha 5 (importin alpha 6) 0.229775
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.229775
ADGRG5 adhesion G protein-coupled receptor G5 0.229775
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.229703
PPP6R1 protein phosphatase 6, regulatory subunit 1 0.22949
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.22942
XDH xanthine dehydrogenase 0.22914
THAP10 THAP domain containing 10 0.229071
TBL2 transducin (beta)-like 2 0.229071
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.229071
F13A1 coagulation factor XIII, A1 polypeptide 0.228934
ATP10B ATPase, class V, type 10B 0.228764
FRMD4A FERM domain containing 4A 0.22873
DEXI Dexi homolog (mouse) 0.228428
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.228067
NRXN2 neurexin 2 0.228067
MSH5 mutS homolog 5 0.228067
PPARD peroxisome proliferator-activated receptor delta 0.227905
TBXAS1 thromboxane A synthase 1 (platelet) 0.227745
PACRG PARK2 co-regulated 0.227745
PRICKLE2 prickle homolog 2 (Drosophila) 0.227428
ERBB4 erb-b2 receptor tyrosine kinase 4 0.22721
TULP1 tubby like protein 1 0.227118
APOB apolipoprotein B 0.227118
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.227118
NPAS3 neuronal PAS domain protein 3 0.227118
STAU2 staufen double-stranded RNA binding protein 2 0.226813
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.226813
SP140 SP140 nuclear body protein 0.226813
FOXP1 forkhead box P1 0.226813
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.226336
COL5A3 collagen, type V, alpha 3 0.225929
ZNF217 zinc finger protein 217 0.225644
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.225644
TMEM159 transmembrane protein 159 0.225364
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.225364
USP6NL USP6 N-terminal like 0.225364
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.225089
L3MBTL4 l(3)mbt-like 4 (Drosophila) 0.225089
GRAP2 GRB2-related adaptor protein 2 0.224288
CDHR5 cadherin-related family member 5 0.224288
MPZL1 myelin protein zero-like 1 0.224106
MACROD2 MACRO domain containing 2 0.224029
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 0.223774
C11ORF44 chromosome 11 open reading frame 44 0.223698
SPATA17 spermatogenesis associated 17 0.223498
TM4SF4 transmembrane 4 L six family member 4 0.223032
N4BP1 NEDD4 binding protein 1 0.222554
LOC100506274 uncharacterized LOC100506274 0.222554
OXR1 oxidation resistance 1 0.222554
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.222483
LHFPL3 lipoma HMGIC fusion partner-like 3 0.22239
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.221862
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.221637
CDH18 cadherin 18, type 2 0.221284
CCDC81 coiled-coil domain containing 81 0.221197
TMC1 transmembrane channel-like 1 0.220767
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.220767
EXT2 exostosin glycosyltransferase 2 0.220349
FOXN3 forkhead box N3 0.220349
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 0.220349
TCTEX1D1 Tctex1 domain containing 1 0.220143
KLHDC7A kelch domain containing 7A 0.220143
SLC22A23 solute carrier family 22, member 23 0.220143
GADL1 glutamate decarboxylase-like 1 0.220143
GLRX3 glutaredoxin 3 0.220143
LARP6 La ribonucleoprotein domain family, member 6 0.21974
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 0.21974
FSTL4 follistatin-like 4 0.219541
DOCK1 dedicator of cytokinesis 1 0.219346
SAMD12 sterile alpha motif domain containing 12 0.219248
PBX1 pre-B-cell leukemia homeobox 1 0.21879
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 0.218771
KDM1B lysine (K)-specific demethylase 1B 0.218771
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.218771
SMYD3 SET and MYND domain containing 3 0.218771
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.218771
DCDC2 doublecortin domain containing 2 0.218621
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.218509
COL25A1 collagen, type XXV, alpha 1 0.218325
APP amyloid beta (A4) precursor protein 0.218215
THSD4 thrombospondin, type I, domain containing 4 0.218215
KCNIP4 Kv channel interacting protein 4 0.218016
LIN7A lin-7 homolog A (C. elegans) 0.217766
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.217678
PCDH9 protocadherin 9 0.217642
LOC100507462 uncharacterized LOC100507462 0.206985
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.202622