multiple myeloma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A myeloma that is located_in the plasma cells in bone marrow. (Human Disease Ontology, DOID_9538)
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Genes

637 genes co-occuring with the disease multiple myeloma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
B2M beta-2-microglobulin 2.31173
IL6 interleukin 6 2.16602
CD34 CD34 molecule 2.15302
CD38 CD38 molecule 2.12815
CD79A CD79a molecule, immunoglobulin-associated alpha 2.12765
FGFR3 fibroblast growth factor receptor 3 1.90521
CD19 CD19 molecule 1.69996
MAEA macrophage erythroblast attacher 1.68408
NCAM1 neural cell adhesion molecule 1 1.67548
SDC1 syndecan 1 1.66961
CCND1 cyclin D1 1.62067
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.61889
CRBN cereblon 1.58225
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.53833
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.52908
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.51896
IL6R interleukin 6 receptor 1.50623
IRF4 interferon regulatory factor 4 1.49438
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.48779
ALB albumin 1.47154
CSF3 colony stimulating factor 3 (granulocyte) 1.46803
TP53 tumor protein p53 1.46012
BCL2L1 BCL2-like 1 1.45089
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45089
CKS1B CDC28 protein kinase regulatory subunit 1B 1.38865
CDKN2A cyclin-dependent kinase inhibitor 2A 1.37338
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.36989
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.34592
ANXA5 annexin A5 1.33283
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.32236
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.30314
HRAS Harvey rat sarcoma viral oncogene homolog 1.29396
MAGEC1 melanoma antigen family C1 1.29134
CTRL chymotrypsin-like 1.28959
IFNA1 interferon, alpha 1 1.28741
IGF1 insulin-like growth factor 1 (somatomedin C) 1.28741
CCND2 cyclin D2 1.28479
CCL3 chemokine (C-C motif) ligand 3 1.28392
CD40 CD40 molecule, TNF receptor superfamily member 5 1.28086
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.27344
XBP1 X-box binding protein 1 1.26691
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.2656
WHSC1 Wolf-Hirschhorn syndrome candidate 1 1.24341
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.22388
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.22042
CXCL12 chemokine (C-X-C motif) ligand 12 1.20569
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.20266
BST2 bone marrow stromal cell antigen 2 1.18841
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.18712
CRP C-reactive protein, pentraxin-related 1.15666
VEGFA vascular endothelial growth factor A 1.15666
INA internexin neuronal intermediate filament protein, alpha 1.15496
BIRC5 baculoviral IAP repeat containing 5 1.14942
CD4 CD4 molecule 1.14645
ALPPL2 alkaline phosphatase, placental-like 2 1.13628
ALPP alkaline phosphatase, placental 1.13585
ALPL alkaline phosphatase, liver/bone/kidney 1.13543
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.12614
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.12614
SLAMF7 SLAM family member 7 1.11225
IFNA2 interferon, alpha 2 1.10846
SPA17 sperm autoantigenic protein 17 1.10636
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.103
BAX BCL2-associated X protein 1.10216
HDAC9 histone deacetylase 9 1.08621
CD44 CD44 molecule (Indian blood group) 1.07698
BGLAP bone gamma-carboxyglutamate (gla) protein 1.05303
TNF tumor necrosis factor 1.04251
FN1 fibronectin 1 1.04167
PARP1 poly (ADP-ribose) polymerase 1 1.04125
ICAM1 intercellular adhesion molecule 1 1.02608
CCND3 cyclin D3 1.02355
IL1B interleukin 1, beta 1.01934
IGF1R insulin-like growth factor 1 receptor 1.01512
EPO erythropoietin 1.00372
CD27 CD27 molecule 1.00246
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.998236
JAK2 Janus kinase 2 0.988114
MUC1 mucin 1, cell surface associated 0.9839
JUN jun proto-oncogene 0.978426
FGF2 fibroblast growth factor 2 (basic) 0.976744
IL2 interleukin 2 0.96918
ACPP acid phosphatase, prostate 0.95996
CD33 CD33 molecule 0.948269
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.947852
BCL2 B-cell CLL/lymphoma 2 0.946603
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.945354
IGLV7-43 immunoglobulin lambda variable 7-43 0.944106
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.94369
RB1 retinoblastoma 1 0.943274
HLA-G major histocompatibility complex, class I, G 0.93497
MYEOV myeloma overexpressed 0.931242
BIRC2 baculoviral IAP repeat containing 2 0.922149
HDAC4 histone deacetylase 4 0.909787
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.883521
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.882292
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.877376
CDK9 cyclin-dependent kinase 9 0.870415
DIABLO diablo, IAP-binding mitochondrial protein 0.870006
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.863865
CD5 CD5 molecule 0.858134
CD3EAP CD3e molecule, epsilon associated protein 0.857315
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.852402
CCR1 chemokine (C-C motif) receptor 1 0.847898
DAZAP2 DAZ associated protein 2 0.841753
HLA-C major histocompatibility complex, class I, C 0.840934
JAG2 jagged 2 0.834788
BCL6 B-cell CLL/lymphoma 6 0.833968
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.833148
MAGEA3 melanoma antigen family A3 0.825768
PRDM1 PR domain containing 1, with ZNF domain 0.821257
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.821257
TRAF3 TNF receptor-associated factor 3 0.820437
CXCR4 chemokine (C-X-C motif) receptor 4 0.818385
CD9 CD9 molecule 0.80936
CD40LG CD40 ligand 0.802795
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.800333
IL3 interleukin 3 0.791721
BIRC3 baculoviral IAP repeat containing 3 0.791311
PTHLH parathyroid hormone-like hormone 0.789672
PAX5 paired box 5 0.789262
MYO1G myosin IG 0.786803
PGRMC1 progesterone receptor membrane component 1 0.786394
PTH parathyroid hormone 0.785574
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.782707
CCR4 chemokine (C-C motif) receptor 4 0.779023
CCR7 chemokine (C-C motif) receptor 7 0.777386
CXCL9 chemokine (C-X-C motif) ligand 9 0.767167
OSM oncostatin M 0.766759
BCL9 B-cell CLL/lymphoma 9 0.765943
VCAM1 vascular cell adhesion molecule 1 0.755342
CD80 CD80 molecule 0.752492
NOTCH1 notch 1 0.752492
LYZ lysozyme 0.74883
MCL1 myeloid cell leukemia 1 0.746391
KRAS Kirsten rat sarcoma viral oncogene homolog 0.743954
F8 coagulation factor VIII, procoagulant component 0.743141
HLA-A major histocompatibility complex, class I, A 0.741923
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 0.741923
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.736243
ERN1 endoplasmic reticulum to nucleus signaling 1 0.733406
SPP1 secreted phosphoprotein 1 0.731381
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.727333
AGO2 argonaute RISC catalytic component 2 0.72612
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.724098
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.708767
ITGB7 integrin, beta 7 0.70233
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.701124
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.700321
FASLG Fas ligand (TNF superfamily, member 6) 0.699919
MMP9 matrix metallopeptidase 9 0.696306
WWOX WW domain containing oxidoreductase 0.695103
AURKA aurora kinase A 0.6939
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.693499
USHBP1 Usher syndrome 1C binding protein 1 0.692296
FBXL20 F-box and leucine-rich repeat protein 20 0.686291
VWF von Willebrand factor 0.685891
ZDHHC9 zinc finger, DHHC-type containing 9 0.685491
FRZB frizzled-related protein 0.680297
CD226 CD226 molecule 0.680297
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.679898
SOST sclerostin 0.667152
B3GAT1 beta-1,3-glucuronyltransferase 1 0.667152
IL4 interleukin 4 0.666755
GPRC5D G protein-coupled receptor, class C, group 5, member D 0.666358
TFRC transferrin receptor 0.665563
CD86 CD86 molecule 0.664372
SFRP2 secreted frizzled-related protein 2 0.66199
RNF167 ring finger protein 167 0.65763
FXYD5 FXYD domain containing ion transport regulator 5 0.657234
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.656837
ATF4 activating transcription factor 4 0.654463
MAPK3 mitogen-activated protein kinase 3 0.650903
FLT1 fms-related tyrosine kinase 1 0.646559
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.64577
GRB2 growth factor receptor-bound protein 2 0.640645
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.635921
STAT1 signal transducer and activator of transcription 1, 91kDa 0.634349
ZHX2 zinc fingers and homeoboxes 2 0.631598
CD22 CD22 molecule 0.630027
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.62885
IL11 interleukin 11 0.623751
BTK Bruton agammaglobulinemia tyrosine kinase 0.622183
PRF1 perforin 1 (pore forming protein) 0.6214
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.6214
TACC1 transforming, acidic coiled-coil containing protein 1 0.619051
LTA lymphotoxin alpha 0.611229
JAK1 Janus kinase 1 0.609666
APAF1 apoptotic peptidase activating factor 1 0.609666
MET MET proto-oncogene, receptor tyrosine kinase 0.607714
BIK BCL2-interacting killer (apoptosis-inducing) 0.606933
SP7 Sp7 transcription factor 0.604981
CD52 CD52 molecule 0.604201
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.60342
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.60342
ANG angiogenin, ribonuclease, RNase A family, 5 0.60069
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.598351
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.597571
NOP2 NOP2 nucleolar protein 0.594843
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.594064
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.591727
FAM46C family with sequence similarity 46, member C 0.589779
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.585497
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.583552
MAPK8 mitogen-activated protein kinase 8 0.583552
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.582384
HSPA4 heat shock 70kDa protein 4 0.581996
HDAC6 histone deacetylase 6 0.581217
C1ORF35 chromosome 1 open reading frame 35 0.57655
TBRG4 transforming growth factor beta regulator 4 0.57655
DTX4 deltex 4, E3 ubiquitin ligase 0.57655
FAM179B family with sequence similarity 179, member B 0.57655
PTPRD protein tyrosine phosphatase, receptor type, D 0.575772
TACC3 transforming, acidic coiled-coil containing protein 3 0.57305
OAF OAF homolog (Drosophila) 0.572662
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.567997
PRAME preferentially expressed antigen in melanoma 0.56722
WNT3A wingless-type MMTV integration site family, member 3A 0.56722
MGP matrix Gla protein 0.566054
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.562558
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.558285
MMP2 matrix metallopeptidase 2 0.557509
CD81 CD81 molecule 0.55712
CTAG2 cancer/testis antigen 2 0.55712
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.556732
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.555956
RUNX2 runt-related transcription factor 2 0.554403
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.550911
H3F3A H3 histone, family 3A 0.548971
H3F3B H3 histone, family 3B (H3.3B) 0.548971
CALCA calcitonin-related polypeptide alpha 0.548195
ANGPT2 angiopoietin 2 0.545093
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.544705
F3 coagulation factor III (thromboplastin, tissue factor) 0.54393
GDF15 growth differentiation factor 15 0.53928
ANGPT1 angiopoietin 1 0.53928
CDK6 cyclin-dependent kinase 6 0.538893
PAX2 paired box 2 0.531154
BDNF brain-derived neurotrophic factor 0.529608
CDK4 cyclin-dependent kinase 4 0.527676
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.52343
AURKB aurora kinase B 0.520346
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.519961
CHEK1 checkpoint kinase 1 0.519575
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 0.51842
BMP2 bone morphogenetic protein 2 0.518034
UBE3C ubiquitin protein ligase E3C 0.515725
IL16 interleukin 16 0.514186
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.51188
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 0.510728
TGFB1 transforming growth factor, beta 1 0.507273
ENDOG endonuclease G 0.503824
GLIPR1L2 GLI pathogenesis-related 1 like 2 0.502675
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.502292
UMOD uromodulin 0.501527
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.498085
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.497321
HPSE heparanase 0.496175
TBX1 T-box 1 0.495029
CD24 CD24 molecule 0.495029
IL1A interleukin 1, alpha 0.489311
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 0.489311
FOXP3 forkhead box P3 0.488549
LAMP1 lysosomal-associated membrane protein 1 0.487027
GBA glucosidase, beta, acid 0.484744
H2AFX H2A histone family, member X 0.483985
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.482844
GPATCH4 G patch domain containing 4 0.482464
PDCD5 programmed cell death 5 0.480945
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.480566
CCNB1 cyclin B1 0.480186
RAP1A RAP1A, member of RAS oncogene family 0.479047
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.479047
IGH immunoglobulin heavy locus 0.474498
PARK2 parkin RBR E3 ubiquitin protein ligase 0.474498
MICA MHC class I polypeptide-related sequence A 0.472604
KDR kinase insert domain receptor 0.469954
SSX1 synovial sarcoma, X breakpoint 1 0.469576
CD58 CD58 molecule 0.468063
FOS FBJ murine osteosarcoma viral oncogene homolog 0.465794
NOG noggin 0.462394
SSX4 synovial sarcoma, X breakpoint 4 0.460506
SSX4B synovial sarcoma, X breakpoint 4B 0.460506
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.460506
HLA-B major histocompatibility complex, class I, B 0.457487
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.45447
KIAA1551 KIAA1551 0.45447
IBSP integrin-binding sialoprotein 0.454093
FLT3 fms-related tyrosine kinase 3 0.452585
TLR1 toll-like receptor 1 0.451454
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.451454
DDIT3 DNA-damage-inducible transcript 3 0.448817
RAB8B RAB8B, member RAS oncogene family 0.448441
FGF1 fibroblast growth factor 1 (acidic) 0.446558
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.445429
PTEN phosphatase and tensin homolog 0.445052
CD83 CD83 molecule 0.4443
SRGN serglycin 0.443171
PSORS1C2 psoriasis susceptibility 1 candidate 2 0.441666
CCPG1 cell cycle progression 1 0.441666
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.44129
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.440538
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.437154
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.436402
THPO thrombopoietin 0.434899
PTK2B protein tyrosine kinase 2 beta 0.428891
DAP death-associated protein 0.426265
FAM53B family with sequence similarity 53, member B 0.425514
MED31 mediator complex subunit 31 0.42289
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.421765
IGHV3-9 immunoglobulin heavy variable 3-9 0.420641
CA13 carbonic anhydrase XIII 0.41727
PIAS3 protein inhibitor of activated STAT, 3 0.415398
BRD4 bromodomain containing 4 0.415024
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.413527
BAGE2 B melanoma antigen family, member 2 0.412779
ORC4 origin recognition complex, subunit 4 0.412779
DEPTOR DEP domain containing MTOR-interacting protein 0.412405
TYRO3 TYRO3 protein tyrosine kinase 0.412031
COL18A1 collagen, type XVIII, alpha 1 0.410909
TTI1 TELO2 interacting protein 1 0.410161
PTPRC protein tyrosine phosphatase, receptor type, C 0.409414
XPO1 exportin 1 0.407545
SSX5 synovial sarcoma, X breakpoint 5 0.403811
HOXB7 homeobox B7 0.403064
TELO2 telomere maintenance 2 0.401945
MAG myelin associated glycoprotein 0.400826
CD47 CD47 molecule 0.398589
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.397471
IGHV4-34 immunoglobulin heavy variable 4-34 0.396353
UBA1 ubiquitin-like modifier activating enzyme 1 0.390397
TACC2 transforming, acidic coiled-coil containing protein 2 0.389653
TF transferrin 0.388909
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.387794
DDB1 damage-specific DNA binding protein 1, 127kDa 0.384822
HAS1 hyaluronan synthase 1 0.384451
AKAP4 A kinase (PRKA) anchor protein 4 0.384079
ASF1B anti-silencing function 1B histone chaperone 0.382966
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.382594
IVNS1ABP influenza virus NS1A binding protein 0.382223
HP haptoglobin 0.381481
IL2RA interleukin 2 receptor, alpha 0.379626
ATF3 activating transcription factor 3 0.378514
GLIPR1L1 GLI pathogenesis-related 1 like 1 0.377773
USP47 ubiquitin specific peptidase 47 0.377773
HPR haptoglobin-related protein 0.37555
ATP8B4 ATPase, class I, type 8B, member 4 0.375179
MSH6 mutS homolog 6 0.374438
ICK intestinal cell (MAK-like) kinase 0.374068
CD69 CD69 molecule 0.374068
NBEA neurobeachin 0.372958
SEMG1 semenogelin I 0.371847
SPACA3 sperm acrosome associated 3 0.371107
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.371107
CDC25A cell division cycle 25A 0.369997
ZNF292 zinc finger protein 292 0.369997
BCR breakpoint cluster region 0.367779
IGHV4-39 immunoglobulin heavy variable 4-39 0.36704
CD37 CD37 molecule 0.366301
IGHV5-51 immunoglobulin heavy variable 5-51 0.364085
NRG3 neuregulin 3 0.363347
FBXO9 F-box protein 9 0.362978
CD200 CD200 molecule 0.362239
MAGEA1 melanoma antigen family A1 0.360764
BCL10 B-cell CLL/lymphoma 10 0.359657
HBA2 hemoglobin, alpha 2 0.359289
HBA1 hemoglobin, alpha 1 0.357077
MAPK9 mitogen-activated protein kinase 9 0.355972
ZMAT4 zinc finger, matrin-type 4 0.355604
RAD51 RAD51 recombinase 0.351923
TEX14 testis expressed 14 0.351187
MYD88 myeloid differentiation primary response 88 0.351187
IGHV3-30 immunoglobulin heavy variable 3-30 0.344207
PCNA proliferating cell nuclear antigen 0.344207
PLAU plasminogen activator, urokinase 0.341639
BCL7C B-cell CLL/lymphoma 7C 0.341272
HAMP hepcidin antimicrobial peptide 0.340906
GPR26 G protein-coupled receptor 26 0.340906
YY1 YY1 transcription factor 0.340539
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.340539
RAB8A RAB8A, member RAS oncogene family 0.340539
CCR2 chemokine (C-C motif) receptor 2 0.340173
UBE2H ubiquitin-conjugating enzyme E2H 0.335046
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.334315
PLK1 polo-like kinase 1 0.333583
PLD5 phospholipase D family, member 5 0.332121
ANKHD1 ankyrin repeat and KH domain containing 1 0.331025
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.33066
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.3292
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.328469
SFRP1 secreted frizzled-related protein 1 0.326281
ULK4 unc-51 like kinase 4 0.325187
BAG2 BCL2-associated athanogene 2 0.324458
SH2D1A SH2 domain containing 1A 0.321909
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.320817
CUL4A cullin 4A 0.320817
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.319363
COL21A1 collagen, type XXI, alpha 1 0.318999
CAMLG calcium modulating ligand 0.317182
PIDD1 p53-induced death domain protein 1 0.316456
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.315729
FBXL5 F-box and leucine-rich repeat protein 5 0.315729
DAPK2 death-associated protein kinase 2 0.315729
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.315003
DIS3L DIS3 like exosome 3'-5' exoribonuclease 0.312464
TRIM13 tripartite motif containing 13 0.312464
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 0.312464
CDK1 cyclin-dependent kinase 1 0.311377
FTH1 ferritin, heavy polypeptide 1 0.311014
CHL1 cell adhesion molecule L1-like 0.311014
FTL ferritin, light polypeptide 0.311014
CARS cysteinyl-tRNA synthetase 0.309566
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.309204
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.307757
YBX1 Y box binding protein 1 0.307757
IFNA7 interferon, alpha 7 0.30631
NUF2 NUF2, NDC80 kinetochore complex component 0.305948
CD70 CD70 molecule 0.305948
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.305587
MICB MHC class I polypeptide-related sequence B 0.305226
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.304503
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.304503
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.304503
TLR10 toll-like receptor 10 0.303059
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.303059
BLNK B-cell linker 0.301615
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.301254
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.298731
CTSK cathepsin K 0.296211
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.295851
SAA1 serum amyloid A1 0.294413
ANXA2R annexin A2 receptor 0.289386
CD68 CD68 molecule 0.289386
IGHV1-2 immunoglobulin heavy variable 1-2 0.289027
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.28831
ADA adenosine deaminase 0.287235
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.287235
CT45A1 cancer/testis antigen family 45, member A1 0.286519
FGFR1 fibroblast growth factor receptor 1 0.283655
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.283655
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.283297
DLL1 delta-like 1 (Drosophila) 0.283297
DNTT DNA nucleotidylexotransferase 0.28294
LCK LCK proto-oncogene, Src family tyrosine kinase 0.280439
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.280082
OAT ornithine aminotransferase 0.280082
JAG1 jagged 1 0.279011
ZFAND2A zinc finger, AN1-type domain 2A 0.278654
FGFR2 fibroblast growth factor receptor 2 0.27687
BTBD2 BTB (POZ) domain containing 2 0.276514
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.276158
MEGF9 multiple EGF-like-domains 9 0.276158
GPSM1 G-protein signaling modulator 1 0.272953
TLR9 toll-like receptor 9 0.272953
WSB2 WD repeat and SOCS box containing 2 0.271886
FGFR4 fibroblast growth factor receptor 4 0.269043
VPREB3 pre-B lymphocyte 3 0.269043
CYLD cylindromatosis (turban tumor syndrome) 0.268332
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.267267
PVR poliovirus receptor 0.266203
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.264431
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.263368
TTR transthyretin 0.263368
VCY1B variable charge, Y-linked 1B 0.261599
GBP3 guanylate binding protein 3 0.261599
VCY variable charge, Y-linked 0.261599
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 0.260184
IL25 interleukin 25 0.25983
HBEGF heparin-binding EGF-like growth factor 0.25983
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.25877
ICAM3 intercellular adhesion molecule 3 0.25877
IL17A interleukin 17A 0.258417
PF4 platelet factor 4 0.257358
MIR21 microRNA 21 0.257358
ANXA2 annexin A2 0.257005
ZBTB20 zinc finger and BTB domain containing 20 0.256652
JUND jun D proto-oncogene 0.255594
PREB prolactin regulatory element binding 0.253831
NUAK1 NUAK family, SNF1-like kinase, 1 0.25207
MVP major vault protein 0.250311
TUG1 taurine up-regulated 1 (non-protein coding) 0.249257
TOP1 topoisomerase (DNA) I 0.248905
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.246448
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.245396
LRP5 low density lipoprotein receptor-related protein 5 0.244696
F2 coagulation factor II (thrombin) 0.244345
AKAP11 A kinase (PRKA) anchor protein 11 0.244345
ATF6 activating transcription factor 6 0.243995
BECN1 beclin 1, autophagy related 0.243645
RAG2 recombination activating gene 2 0.242595
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.240497
CD1D CD1d molecule 0.239799
XCL2 chemokine (C motif) ligand 2 0.239799
EPOR erythropoietin receptor 0.23945
SKP1 S-phase kinase-associated protein 1 0.239101
ZNF287 zinc finger protein 287 0.237706
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.23666
ACVR2A activin A receptor, type IIA 0.235964
CST3 cystatin C 0.235616
PPARG peroxisome proliferator-activated receptor gamma 0.235268
CDK2 cyclin-dependent kinase 2 0.234573
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.233183
NCR1 natural cytotoxicity triggering receptor 1 0.232489
SELPLG selectin P ligand 0.22937
GSTTP1 glutathione S-transferase theta pseudogene 1 0.229024
GSTT1 glutathione S-transferase theta 1 0.229024
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.227988
TUBA1A tubulin, alpha 1a 0.227297
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.226952
FOXP1 forkhead box P1 0.225917
PPT1 palmitoyl-protein thioesterase 1 0.225573
SCARA3 scavenger receptor class A, member 3 0.225229
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.225229
CDAN1 codanin 1 0.22454
KREMEN2 kringle containing transmembrane protein 2 0.223853
TNK2 tyrosine kinase, non-receptor, 2 0.222822
PNMA2 paraneoplastic Ma antigen 2 0.222479
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.222136
RARA retinoic acid receptor, alpha 0.221793
ATG13 autophagy related 13 0.22145
COL1A2 collagen, type I, alpha 2 0.220424
INHBE inhibin, beta E 0.219398
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.218715
ATM ATM serine/threonine kinase 0.218374
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.217352
NAAA N-acylethanolamine acid amidase 0.217352
C1QBP complement component 1, q subcomponent binding protein 0.217012
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.216672
SP1 Sp1 transcription factor 0.214297
COPS3 COP9 signalosome subunit 3 0.213959
TRAF1 TNF receptor-associated factor 1 0.213959
CSF1R colony stimulating factor 1 receptor 0.210925
HGFAC HGF activator 0.210925
CDC25C cell division cycle 25C 0.210589
IPO4 importin 4 0.210253
WBSCR22 Williams Beuren syndrome chromosome region 22 0.208914
EIF4E eukaryotic translation initiation factor 4E 0.206913
CXCR3 chemokine (C-X-C motif) receptor 3 0.205916
IRF1 interferon regulatory factor 1 0.205916
CCDC110 coiled-coil domain containing 110 0.205585
CIITA class II, major histocompatibility complex, transactivator 0.205254
IL15 interleukin 15 0.204593
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 0.204263
CNTN6 contactin 6 0.203933
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.203275
MIRLET7E microRNA let-7e 0.202946
CDC20 cell division cycle 20 0.201962
BTBD3 BTB (POZ) domain containing 3 0.200656
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.200331
EGLN1 egl-9 family hypoxia-inducible factor 1 0.200331
IARS isoleucyl-tRNA synthetase 0.198709
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.198709
IL10 interleukin 10 0.198064
LYN LYN proto-oncogene, Src family tyrosine kinase 0.197742
CCL2 chemokine (C-C motif) ligand 2 0.196459
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 0.19582
PCDH10 protocadherin 10 0.19582
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.195183
CD79B CD79b molecule, immunoglobulin-associated beta 0.194548
TIGAR TP53 induced glycolysis regulatory phosphatase 0.194232
CD46 CD46 molecule, complement regulatory protein 0.193915
TRAF5 TNF receptor-associated factor 5 0.192344
PROM1 prominin 1 0.191408
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.191097
AICDA activation-induced cytidine deaminase 0.190786
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.190786
CSN1S1 casein alpha s1 0.190786
KITLG KIT ligand 0.189551
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.188938
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.188632
DSCR8 Down syndrome critical region 8 0.188022
BAG3 BCL2-associated athanogene 3 0.187113
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.187113
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.187113
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.185612
SIRT1 sirtuin 1 0.185313
EGR1 early growth response 1 0.182957
TUBG1 tubulin, gamma 1 0.182086
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.181798
KLHL20 kelch-like family member 20 0.180367
ING4 inhibitor of growth family, member 4 0.178682
HDAC1 histone deacetylase 1 0.176757
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 0.175947
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.175411
S1PR1 sphingosine-1-phosphate receptor 1 0.175146
TSC22D3 TSC22 domain family, member 3 0.174617
PSME4 proteasome (prosome, macropain) activator subunit 4 0.173314
NCAPG non-SMC condensin I complex, subunit G 0.173057
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.172799
IL6ST interleukin 6 signal transducer 0.172544
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.172038
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.171785
SEZ6L seizure related 6 homolog (mouse)-like 0.171036
BRD2 bromodomain containing 2 0.171036
C6ORF25 chromosome 6 open reading frame 25 0.170054
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.169812
HDAC2 histone deacetylase 2 0.169571
AHSG alpha-2-HS-glycoprotein 0.169571
RET ret proto-oncogene 0.169571
CYGB cytoglobin 0.16933
CDK19 cyclin-dependent kinase 19 0.168148
MAPK14 mitogen-activated protein kinase 14 0.168148
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.167224
FAS Fas cell surface death receptor 0.166319
WWTR1 WW domain containing transcription regulator 1 0.166095
KIF21B kinesin family member 21B 0.165655
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.165217
TMEM11 transmembrane protein 11 0.164786
FCRL5 Fc receptor-like 5 0.164149
SEPT8 septin 8 0.163729
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.163523
PXN paxillin 0.163317
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.163317
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.163111
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.162707
CD7 CD7 molecule 0.161912
CXCL5 chemokine (C-X-C motif) ligand 5 0.161912
CYR61 cysteine-rich, angiogenic inducer, 61 0.161716
ENG endoglin 0.160948
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.160948
WT1 Wilms tumor 1 0.160574
NCR2 natural cytotoxicity triggering receptor 2 0.160574
IL1RN interleukin 1 receptor antagonist 0.160387
COASY CoA synthase 0.160021
HK2 hexokinase 2 0.158778
CD247 CD247 molecule 0.158778
CD200R1 CD200 receptor 1 0.142991
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.141939
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.140763
PORCN porcupine homolog (Drosophila) 0.140489
CARD17 caspase recruitment domain family, member 17 0.140096
VCAN versican 0.138471
CFP complement factor properdin 0.138004
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.137863
GUSB glucuronidase, beta 0.134551
PLG plasminogen 0.13433
CFH complement factor H 0.127429