multinodular goiter Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A goiter characterized by a multinodular enlargement of the thyroid gland. (Human Disease Ontology, DOID_0050489)
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Genes

81 genes co-occuring with the disease multinodular goiter in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TG thyroglobulin 1.85821
TSHR thyroid stimulating hormone receptor 1.7496
TPO thyroid peroxidase 1.39477
TRH thyrotropin-releasing hormone 1.30357
CALCA calcitonin-related polypeptide alpha 1.26473
PTH parathyroid hormone 1.14687
DICER1 dicer 1, ribonuclease type III 1.10552
LYPD1 LY6/PLAUR domain containing 1 1.03535
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.999503
UNG uracil-DNA glycosylase 0.859771
TDG thymine-DNA glycosylase 0.829049
RET ret proto-oncogene 0.826589
KRT19 keratin 19, type I 0.787213
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.781888
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.77575
LGALS3 lectin, galactoside-binding, soluble, 3 0.767985
CYS1 cystin 1 0.73746
GNAS GNAS complex locus 0.736243
NKX2-1 NK2 homeobox 1 0.707559
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.699517
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.67551
SERP1 stress-associated endoplasmic reticulum protein 1 0.648533
PTEN phosphatase and tensin homolog 0.647743
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.628457
PAAF1 proteasomal ATPase-associated factor 1 0.616312
MIR222 microRNA 222 0.57305
RXRB retinoid X receptor, beta 0.557509
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.546256
PROK1 prokineticin 1 0.540829
CXCL10 chemokine (C-X-C motif) ligand 10 0.526904
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.484744
MCM3 minichromosome maintenance complex component 3 0.465416
PCSK2 proprotein convertase subtilisin/kexin type 2 0.455978
TRIB1 tribbles pseudokinase 1 0.455978
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.442795
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.416521
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.394491
THEM5 thioesterase superfamily member 5 0.393001
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.370737
CD3D CD3d molecule, delta (CD3-TCR complex) 0.362609
PAX8 paired box 8 0.352659
TNS1 tensin 1 0.349349
SHBG sex hormone-binding globulin 0.342372
PRDM16 PR domain containing 16 0.328105
CTSB cathepsin B 0.306672
IL16 interleukin 16 0.297651
PROK2 prokineticin 2 0.297651
FLNB filamin B, beta 0.295492
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.291898
CLEC4C C-type lectin domain family 4, member C 0.284728
CCL13 chemokine (C-C motif) ligand 13 0.27794
BGLAP bone gamma-carboxyglutamate (gla) protein 0.275445
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.275089
CXCL14 chemokine (C-X-C motif) ligand 14 0.274376
DYNLT1 dynein, light chain, Tctex-type 1 0.274021
SST somatostatin 0.265494
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.261599
IGF1 insulin-like growth factor 1 (somatomedin C) 0.251718
TXNRD2 thioredoxin reductase 2 0.251366
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.246448
CP ceruloplasmin (ferroxidase) 0.244696
GPX5 glutathione peroxidase 5 0.240847
GPX4 glutathione peroxidase 4 0.238054
HNMT histamine N-methyltransferase 0.235964
GPX1 glutathione peroxidase 1 0.223853
PRDX2 peroxiredoxin 2 0.217012
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.209918
CD40 CD40 molecule, TNF receptor superfamily member 5 0.196779
TGFB1 transforming growth factor, beta 1 0.191408
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.189551
FASLG Fas ligand (TNF superfamily, member 6) 0.18651
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.181222
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.181222
PHB prohibitin 0.173314
TPT1 tumor protein, translationally-controlled 1 0.173057
CLEC3A C-type lectin domain family 3, member A 0.172291
CLEC2B C-type lectin domain family 2, member B 0.169091
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.168617
SOD2 superoxide dismutase 2, mitochondrial 0.165874
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.163317
MIR221 microRNA 221 0.159658