multidrug-resistant tuberculosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A tuberculosis that is resistant to isoniazid and rifampicin, the two most powerful first-line anti-TB drugs. (Human Disease Ontology, DOID_401)
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Genes

72 genes co-occuring with the disease multidrug-resistant tuberculosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FRRS1 ferric-chelate reductase 1 1.70724
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) 1.53701
INHA inhibin, alpha 1.3869
CD4 CD4 molecule 1.30925
GNLY granulysin 1.28785
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.28304
FGFBP2 fibroblast growth factor binding protein 2 1.11225
SEPT10 septin 10 1.07572
C11ORF40 chromosome 11 open reading frame 40 0.901567
METAP1 methionyl aminopeptidase 1 0.900335
ILVBL ilvB (bacterial acetolactate synthase)-like 0.891718
AHR aryl hydrocarbon receptor 0.829869
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.825768
SARS seryl-tRNA synthetase 0.819616
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.804436
TRIP10 thyroid hormone receptor interactor 10 0.804026
PRAMEF20 PRAME family member 20 0.802385
FBXO17 F-box protein 17 0.770027
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.767167
EDNRA endothelin receptor type A 0.735838
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.711183
GUK1 guanylate kinase 1 0.703134
GRIK4 glutamate receptor, ionotropic, kainate 4 0.697109
IRF9 interferon regulatory factor 9 0.688291
POU3F2 POU class 3 homeobox 2 0.683892
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.683093
MBD1 methyl-CpG binding domain protein 1 0.681495
AADACL3 arylacetamide deacetylase-like 3 0.680697
SRGN serglycin 0.6791
TST thiosulfate sulfurtransferase (rhodanese) 0.673917
INSC inscuteable homolog (Drosophila) 0.654858
METAP2 methionyl aminopeptidase 2 0.617877
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.59874
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.540442
DHPS deoxyhypusine synthase 0.535409
CYCS cytochrome c, somatic 0.524588
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.507273
PHGDH phosphoglycerate dehydrogenase 0.505356
DCLK3 doublecortin-like kinase 3 0.491978
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.476393
RPS12 ribosomal protein S12 0.466172
MGAT4C MGAT4 family, member C 0.440538
DHFR dihydrofolate reductase 0.438282
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.420266
GPR182 G protein-coupled receptor 182 0.411657
SRCIN1 SRC kinase signaling inhibitor 1 0.399707
SP6 Sp6 transcription factor 0.371477
SPTB spectrin, beta, erythrocytic 0.364454
ADSL adenylosuccinate lyase 0.352291
WAPAL wings apart-like homolog (Drosophila) 0.351187
FOXP3 forkhead box P3 0.350084
IL10 interleukin 10 0.345675
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.342006
TOP3A topoisomerase (DNA) III alpha 0.330295
HAND2 heart and neural crest derivatives expressed 2 0.328834
STAT1 signal transducer and activator of transcription 1, 91kDa 0.320817
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.318272
CD209 CD209 molecule 0.307395
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.307395
PRDX5 peroxiredoxin 5 0.287952
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.25877
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.251718
STAT4 signal transducer and activator of transcription 4 0.237009
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.23492
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.224196
IRF1 interferon regulatory factor 1 0.214975
IL7R interleukin 7 receptor 0.199033
CD63 CD63 molecule 0.199033
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.198709
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.195501
IL2 interleukin 2 0.187719
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.167224