mucus layer Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. (Gene Ontology, GO_0070701)
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Genes

97 proteins co-occuring with the mucus layer cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MUC2 mucin 2, oligomeric mucus/gel-forming 2.81522
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.05976
TFF3 trefoil factor 3 (intestinal) 1.77731
MUC3A mucin 3A, cell surface associated 1.67872
MUC6 mucin 6, oligomeric mucus/gel-forming 1.45873
TFF2 trefoil factor 2 1.45647
MUC4 mucin 4, cell surface associated 1.43951
FCGBP Fc fragment of IgG binding protein 1.36417
TFF1 trefoil factor 1 1.33304
MUC17 mucin 17, cell surface associated 1.32654
MUC1 mucin 1, cell surface associated 1.24865
ZG16 zymogen granule protein 16 1.06903
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1.04281
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 0.995142
ANGPT4 angiopoietin 4 0.862609
MUC13 mucin 13, cell surface associated 0.83781
CD79A CD79a molecule, immunoglobulin-associated alpha 0.836892
RETNLB resistin like beta 0.79652
ADAM29 ADAM metallopeptidase domain 29 0.788733
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 0.779583
REG3G regenerating islet-derived 3 gamma 0.771363
ADSL adenylosuccinate lyase 0.749546
MUC20 mucin 20, cell surface associated 0.711908
TLR5 toll-like receptor 5 0.707039
IGF2-AS IGF2 antisense RNA 0.703067
AGR2 anterior gradient 2 0.691202
MMD2 monocyte to macrophage differentiation-associated 2 0.681155
SPINK1 serine peptidase inhibitor, Kazal type 1 0.672894
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.631598
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.613318
MUC16 mucin 16, cell surface associated 0.601487
GAST gastrin 0.597276
MUC12 mucin 12, cell surface associated 0.589295
LTF lactotransferrin 0.583849
NLRP6 NLR family, pyrin domain containing 6 0.572578
HRH2 histamine receptor H2 0.543176
DMBT1 deleted in malignant brain tumors 1 0.533309
BEST2 bestrophin 2 0.527569
AVPR1B arginine vasopressin receptor 1B 0.508383
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.504724
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.49418
IL10 interleukin 10 0.487711
OLFM4 olfactomedin 4 0.480855
SPDEF SAM pointed domain containing ETS transcription factor 0.480453
AS3MT arsenite methyltransferase 0.47844
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.443689
KLF4 Kruppel-like factor 4 (gut) 0.441312
IL4I1 interleukin 4 induced 1 0.432224
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.428678
DUOXA2 dual oxidase maturation factor 2 0.423174
TSPAN8 tetraspanin 8 0.405193
MUC7 mucin 7, secreted 0.400527
LYZ lysozyme 0.395873
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.377738
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.374666
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.369301
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.340395
ALB albumin 0.340017
MMD monocyte to macrophage differentiation-associated 0.320826
DUOXA1 dual oxidase maturation factor 1 0.313718
PEG3 paternally expressed 3 0.311105
TLR4 toll-like receptor 4 0.30924
RETN resistin 0.305888
PRSS21 protease, serine, 21 (testisin) 0.281821
CAMP cathelicidin antimicrobial peptide 0.281085
KLK6 kallikrein-related peptidase 6 0.278509
REEP5 receptor accessory protein 5 0.269335
IL6 interleukin 6 0.267871
GP2 glycoprotein 2 (zymogen granule membrane) 0.262755
DCLK1 doublecortin-like kinase 1 0.262755
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.26239
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.26239
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.24713
HMGN2 high mobility group nucleosomal binding domain 2 0.240636
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.239197
FGF7 fibroblast growth factor 7 0.236683
CCL7 chemokine (C-C motif) ligand 7 0.236324
KERA keratocan 0.227041
NMS neuromedin S 0.224913
LONP1 lon peptidase 1, mitochondrial 0.224558
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.220321
INS insulin 0.214714
TNF tumor necrosis factor 0.209858
MPO myeloperoxidase 0.191456
SAA2 serum amyloid A2 0.182422
FTL ferritin, light polypeptide 0.177439
ICK intestinal cell (MAK-like) kinase 0.177439
FTH1 ferritin, heavy polypeptide 1 0.176024
KLK1 kallikrein 1 0.175745
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.175188
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.168101
CFB complement factor B 0.164542
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.16233
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.161693
EXOC2 exocyst complex component 2 0.157943
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.157943
CLCA1 chloride channel accessory 1 0.141706