mtor signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description mTOR signaling pathway regulates cellular processes such as translation, ribosome biogenesis, cell growth and autophagy and is regulated or responds to growth factors, energy metabolites and/or levels of nutrients. (Pathway Ontology, PW_0000180)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_mTORPathway
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Genes

24 proteins participating in the mtor signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FKBP1A FK506 binding protein 1A, 12kDa
GH1 growth hormone 1
GHR growth hormone receptor
IRS1 insulin receptor substrate 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PTEN phosphatase and tensin homolog
RHEB Ras homolog enriched in brain
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2