mrna cleavage and polyadenylation specificity factor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. (Gene Ontology, GO_0005847)
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17 proteins co-occuring with the mrna cleavage and polyadenylation specificity factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 2.39187
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 2.1889
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 1.7502
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.67568
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.45364
INTS9 integrator complex subunit 9 1.4097
MPZL2 myelin protein zero-like 2 1.24341
CPSF3L cleavage and polyadenylation specific factor 3-like 1.15723
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 1.06144
EEF1G eukaryotic translation elongation factor 1 gamma 1.03078
STRBP spermatid perinuclear RNA binding protein 0.79927
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.711022
UBA1 ubiquitin-like modifier activating enzyme 1 0.626483
TAT tyrosine aminotransferase 0.492157
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.489327
CDK9 cyclin-dependent kinase 9 0.274468
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.197993