mrna cleavage and polyadenylation specificity factor complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. (Gene Ontology, GO_0005847)
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6 proteins localized to the mrna cleavage and polyadenylation specificity factor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 0.663342
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.663342
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.663342
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.663342
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.663342
FIP1L1 factor interacting with PAPOLA and CPSF1 0.03318