mouth disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A gastrointestinal system disease that is located_in the mouth. (Human Disease Ontology, DOID_403)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:403
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Genes

210 genes associated with the disease mouth disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
SND1 staphylococcal nuclease and tudor domain containing 1 0.96005
GRIK2 glutamate receptor, ionotropic, kainate 2 0.921998
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene) 0.821519
ETV6 ets variant 6 0.814557
PTPRJ protein tyrosine phosphatase, receptor type, J 0.807358
ANKRD17 ankyrin repeat domain 17 0.787916
NFIB nuclear factor I/B 0.78104
ACOXL acyl-CoA oxidase-like 0.755798
DFNA5 deafness, autosomal dominant 5 0.722673
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.687994
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.676035
TRAM2 translocation associated membrane protein 2 0.675898
ZNF395 zinc finger protein 395 0.668836
JAG1 jagged 1 0.656693
CCDC3 coiled-coil domain containing 3 0.654134
KDM1A lysine (K)-specific demethylase 1A 0.637975
DCC DCC netrin 1 receptor 0.630986
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.627273
WWOX WW domain containing oxidoreductase 0.624172
SIM1 single-minded family bHLH transcription factor 1 0.618776
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 0.618776
NELL1 NEL-like 1 (chicken) 0.614068
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.613378
SYK spleen tyrosine kinase 0.59964
FHIT fragile histidine triad 0.59964
SASH1 SAM and SH3 domain containing 1 0.59738
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.596808
CNTNAP2 contactin associated protein-like 2 0.592677
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.588302
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.586586
MMP2 matrix metallopeptidase 2 0.577495
ADK adenosine kinase 0.572791
SOX5 SRY (sex determining region Y)-box 5 0.571834
OPCML opioid binding protein/cell adhesion molecule-like 0.570187
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.568383
SAMD4A sterile alpha motif domain containing 4A 0.560163
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.560163
ATRNL1 attractin-like 1 0.559788
AQR aquarius intron-binding spliceosomal factor 0.559788
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.559788
FGF14 fibroblast growth factor 14 0.559601
CNTN4 contactin 4 0.545546
ZBTB46 zinc finger and BTB domain containing 46 0.544628
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.543994
STRN4 striatin, calmodulin binding protein 4 0.542744
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 0.541061
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.532093
EIF3L eukaryotic translation initiation factor 3, subunit L 0.531884
BMP4 bone morphogenetic protein 4 0.530214
ITSN1 intersectin 1 (SH3 domain protein) 0.529803
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.52866
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.527537
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 0.526798
IRAK3 interleukin-1 receptor-associated kinase 3 0.525584
USP47 ubiquitin specific peptidase 47 0.52333
BCR breakpoint cluster region 0.52115
LOC643406 uncharacterized LOC643406 0.520142
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.516888
PCSK5 proprotein convertase subtilisin/kexin type 5 0.516256
COL25A1 collagen, type XXV, alpha 1 0.51239
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.512193
GRIK4 glutamate receptor, ionotropic, kainate 4 0.509209
GPC5 glypican 5 0.508647
ASIC2 acid sensing (proton gated) ion channel 2 0.507394
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.506889
PTPRG protein tyrosine phosphatase, receptor type, G 0.505613
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.503687
CRYL1 crystallin, lambda 1 0.502091
FTO fat mass and obesity associated 0.501894
NPAS3 neuronal PAS domain protein 3 0.500861
RPTOR regulatory associated protein of MTOR, complex 1 0.500478
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.500469
DOCK1 dedicator of cytokinesis 1 0.498059
TSPEAR thrombospondin-type laminin G domain and EAR repeats 0.497336
TEX14 testis expressed 14 0.482299
MSRB3 methionine sulfoxide reductase B3 0.475719
RNF43 ring finger protein 43 0.464296
HSF5 heat shock transcription factor family member 5 0.444859
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.44344
EDA ectodysplasin A 0.442194
HMGA2 high mobility group AT-hook 2 0.442194
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.428705
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.416984
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.411308
GLT6D1 glycosyltransferase 6 domain containing 1 0.408021
LYZL2 lysozyme-like 2 0.404256
RAD51B RAD51 paralog B 0.39257
C14ORF93 chromosome 14 open reading frame 93 0.39257
DLEU7 deleted in lymphocytic leukemia, 7 0.39257
LOC338667 V-set and immunoglobulin domain-containing protein 10-like 0.389529
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.383582
SKA2 spindle and kinetochore associated complex subunit 2 0.378383
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.371601
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.371601
CDKN3 cyclin-dependent kinase inhibitor 3 0.371601
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.366852
TTLL12 tubulin tyrosine ligase-like family member 12 0.363492
ATXN7L1 ataxin 7-like 1 0.358799
EDAR ectodysplasin A receptor 0.358237
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.356125
ADGRE1 adhesion G protein-coupled receptor E1 0.3553
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.3553
PROM1 prominin 1 0.353799
MPPED2 metallophosphoesterase domain containing 2 0.352979
TENM2 teneurin transmembrane protein 2 0.352461
BIRC5 baculoviral IAP repeat containing 5 0.352461
AAMP angio-associated, migratory cell protein 0.343758
SIDT1 SID1 transmembrane family, member 1 0.343758
BOC BOC cell adhesion associated, oncogene regulated 0.343758
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.343758
THSD4 thrombospondin, type I, domain containing 4 0.343758
NT5DC1 5'-nucleotidase domain containing 1 0.343758
IGF2R insulin-like growth factor 2 receptor 0.343758
LPPR5 lipid phosphate phosphatase-related protein type 5 0.343758
TIMP2 TIMP metallopeptidase inhibitor 2 0.343758
WDR73 WD repeat domain 73 0.343758
OTOF otoferlin 0.343758
FBXO38 F-box protein 38 0.343758
LBP lipopolysaccharide binding protein 0.343758
CES4A carboxylesterase 4A 0.342574
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.339861
PCDH9 protocadherin 9 0.338117
ACTN2 actinin, alpha 2 0.338117
RTEL1 regulator of telomere elongation helicase 1 0.338117
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 0.338117
EXOC2 exocyst complex component 2 0.338117
ELF4 E74-like factor 4 (ets domain transcription factor) 0.338117
CSMD1 CUB and Sushi multiple domains 1 0.338117
FRMD4A FERM domain containing 4A 0.335608
DYM dymeclin 0.333975
GRID1 glutamate receptor, ionotropic, delta 1 0.333975
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.333975
ST20 suppressor of tumorigenicity 20 0.333975
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.333975
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.333975
IL17D interleukin 17D 0.333975
ACTN1 actinin, alpha 1 0.333975
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.333975
CAMTA1 calmodulin binding transcription activator 1 0.33079
MAP3K7CL MAP3K7 C-terminal like 0.33079
SCN2A sodium channel, voltage gated, type II alpha subunit 0.33079
ZNF579 zinc finger protein 579 0.33079
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 0.33079
TGIF1 TGFB-induced factor homeobox 1 0.33079
ETNK2 ethanolamine kinase 2 0.33079
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.33079
LRP1B low density lipoprotein receptor-related protein 1B 0.33079
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.33079
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.33079
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 0.33079
CCDC13 coiled-coil domain containing 13 0.328204
FAM126A family with sequence similarity 126, member A 0.328204
KDM4B lysine (K)-specific demethylase 4B 0.328204
NLGN1 neuroligin 1 0.328204
LOC100132731 uncharacterized LOC100132731 0.328204
NPAP1 nuclear pore associated protein 1 0.328204
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.32603
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.32603
GRIK1 glutamate receptor, ionotropic, kainate 1 0.32603
PVALB parvalbumin 0.32603
MYO16 myosin XVI 0.32603
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.32603
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.325081
RAD51C RAD51 paralog C 0.324993
MTMR4 myotubularin related protein 4 0.323957
THSD7B thrombospondin, type I, domain containing 7B 0.323957
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.323957
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.323957
GPN1 GPN-loop GTPase 1 0.323957
IQSEC1 IQ motif and Sec7 domain 1 0.323513
FOXA1 forkhead box A1 0.323493
ITGA8 integrin, alpha 8 0.322033
HLA-DOA major histocompatibility complex, class II, DO alpha 0.322033
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.322033
PTPRT protein tyrosine phosphatase, receptor type, T 0.322033
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.322033
CDH13 cadherin 13 0.322033
FAM135B family with sequence similarity 135, member B 0.322033
STARD8 StAR-related lipid transfer (START) domain containing 8 0.320931
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.314889
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.312753
ERBB2 erb-b2 receptor tyrosine kinase 2 0.309207
LUZP2 leucine zipper protein 2 0.307701
AK9 adenylate kinase 9 0.307001
OFCC1 orofacial cleft 1 candidate 1 0.306331
TMC3 transmembrane channel-like 3 0.301022
SMTNL2 smoothelin-like 2 0.299147
PLLP plasmolipin 0.297795
DTX3L deltex 3 like, E3 ubiquitin ligase 0.29103
APOLD1 apolipoprotein L domain containing 1 0.289391
THBS4 thrombospondin 4 0.288475
ZBTB24 zinc finger and BTB domain containing 24 0.288475
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.286776
HDAC4 histone deacetylase 4 0.285983
TBC1D10C TBC1 domain family, member 10C 0.285983
MVB12B multivesicular body subunit 12B 0.285753
TRIM37 tripartite motif containing 37 0.28535
DPYD dihydropyrimidine dehydrogenase 0.28498
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.284738
FAM162A family with sequence similarity 162, member A 0.282893
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.280112
MYO5B myosin VB 0.27808
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.276425
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 0.271019
GPR39 G protein-coupled receptor 39 0.267238
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.262874
PLS1 plastin 1 0.252282
RAB3C RAB3C, member RAS oncogene family 0.252134
WWC3 WWC family member 3 0.245523
EML1 echinoderm microtubule associated protein like 1 0.239844