motor neuron disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A neurodegenerative disease that is located_in the motor neurones. (Human Disease Ontology, DOID_231)
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Genes

82 genes associated with the disease motor neuron disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
UNC13A unc-13 homolog A (C. elegans) 0.995303
SUSD2 sushi domain containing 2 0.602429
MOB3B MOB kinase activator 3B 0.544585
C9ORF72 chromosome 9 open reading frame 72 0.52461
WNT9A wingless-type MMTV integration site family, member 9A 0.486425
KIFAP3 kinesin-associated protein 3 0.486425
TIAM1 T-cell lymphoma invasion and metastasis 1 0.464771
CAMK1G calcium/calmodulin-dependent protein kinase IG 0.464771
ZNF746 zinc finger protein 746 0.449873
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.4215
DOCK1 dedicator of cytokinesis 1 0.408752
PBDC1 polysaccharide biosynthesis domain containing 1 0.408752
TNN tenascin N 0.403461
CENPV centromere protein V 0.345945
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.327313
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.311576
KIAA0513 KIAA0513 0.311576
STK36 serine/threonine kinase 36 0.297866
NRXN1 neurexin 1 0.297866
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.297866
LAMA3 laminin, alpha 3 0.285417
PSD3 pleckstrin and Sec7 domain containing 3 0.285417
PPY2P pancreatic polypeptide 2, pseudogene 0.264872
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.264872
C4ORF36 chromosome 4 open reading frame 36 0.264872
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.256228
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.256228
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.256228
SGK223 homolog of rat pragma of Rnd2 0.256228
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.256228
TRIM27 tripartite motif containing 27 0.256228
IFRD1 interferon-related developmental regulator 1 0.197766
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.197766
INTS4 integrator complex subunit 4 0.15771
DPP6 dipeptidyl-peptidase 6 0.15771
FOLH1B folate hydrolase 1B 0.15771
GOLGA8B golgin A8 family, member B 0.15771
CSNK1G3 casein kinase 1, gamma 3 0.15771
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.15771
ATXN1 ataxin 1 0.126165
FAS Fas cell surface death receptor 0.126165
NXPH1 neurexophilin 1 0.126165
C1ORF112 chromosome 1 open reading frame 112 0.126165
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.126165
FMN2 formin 2 0.126165
SELL selectin L 0.126165
PTPRF protein tyrosine phosphatase, receptor type, F 0.100789
ZFP64 ZFP64 zinc finger protein 0.100789
CNOT2 CCR4-NOT transcription complex, subunit 2 0.100789
KDM4A lysine (K)-specific demethylase 4A 0.100789
SUSD1 sushi domain containing 1 0.080593
ERVFRD-1 endogenous retrovirus group FRD, member 1 0.080593
FHDC1 FH2 domain containing 1 0.080593
NRXN3 neurexin 3 0.080593
ZIC5 Zic family member 5 0.064973
SHROOM3 shroom family member 3 0.064973
FAM149A family with sequence similarity 149, member A 0.064973
SCN7A sodium channel, voltage gated, type VII alpha subunit 0.064973
PCSK5 proprotein convertase subtilisin/kexin type 5 0.064973
CNTN4 contactin 4 0.064973
CPNE4 copine IV 0.064973
OR52K3P olfactory receptor, family 52, subfamily K, member 3 pseudogene 0.064973
ZBED9 zinc finger, BED-type containing 9 0.064973
HIATL1 hippocampus abundant transcript-like 1 0.064973
VIL1 villin 1 0.064973
METTL15 methyltransferase like 15 0.052255
C9ORF170 chromosome 9 open reading frame 170 0.052255
SLC39A11 solute carrier family 39, member 11 0.052255
DISC1 disrupted in schizophrenia 1 0.052255
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.052255
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.052255
NT5C1A 5'-nucleotidase, cytosolic IA 0.052255
MORN2 MORN repeat containing 2 0.052255
THSD7A thrombospondin, type I, domain containing 7A 0.052255
RBMS1 RNA binding motif, single stranded interacting protein 1 0.043246
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.043246
OPRD1 opioid receptor, delta 1 0.043246
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.043246
MIR99AHG mir-99a-let-7c cluster host gene 0.043246
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.043246
LIPC lipase, hepatic 0.043246
MYT1L myelin transcription factor 1-like 0.035343