motor cortex Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The region of the cerebral cortex influencing movements of the face, neck and trunk, and arm and leg. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004348)
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Genes

300 proteins co-occuring with the tissue motor cortex in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CTBS chitobiase, di-N-acetyl- 2.53383
MRPS7 mitochondrial ribosomal protein S7 1.87133
CAMP cathelicidin antimicrobial peptide 1.85637
PVALB parvalbumin 1.59869
FOS FBJ murine osteosarcoma viral oncogene homolog 1.5824
CST7 cystatin F (leukocystatin) 1.53382
PTN pleiotrophin 1.48927
BDNF brain-derived neurotrophic factor 1.45193
TARDBP TAR DNA binding protein 1.4496
RTN4 reticulon 4 1.40064
TCEA1 transcription elongation factor A (SII), 1 1.38047
VIM vimentin 1.35177
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.34995
CAPN15 calpain 15 1.33274
AMT aminomethyltransferase 1.31514
CALB1 calbindin 1, 28kDa 1.2774
PORCN porcupine homolog (Drosophila) 1.25279
COX5A cytochrome c oxidase subunit Va 1.23851
SERF1B small EDRK-rich factor 1B (centromeric) 1.23182
SERF1A small EDRK-rich factor 1A (telomeric) 1.23182
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.20422
ACHE acetylcholinesterase (Yt blood group) 1.13944
TES testin LIM domain protein 1.13856
ECI2 enoyl-CoA delta isomerase 2 1.13014
GYPE glycophorin E (MNS blood group) 1.11774
FUS FUS RNA binding protein 1.11686
TMEM245 transmembrane protein 245 1.09253
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 1.07441
EFNB3 ephrin-B3 1.07132
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.0603
C9ORF72 chromosome 9 open reading frame 72 1.05721
CLIP1 CAP-GLY domain containing linker protein 1 1.05677
SOD2 superoxide dismutase 2, mitochondrial 1.05457
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.01725
LIN7B lin-7 homolog B (C. elegans) 1.00327
ORC4 origin recognition complex, subunit 4 0.991509
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.989335
CXXC5 CXXC finger protein 5 0.977182
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.968523
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.960744
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.947378
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.933195
MAPT microtubule-associated protein tau 0.905404
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.896895
ATF6B activating transcription factor 6 beta 0.882051
TH tyrosine hydroxylase 0.876974
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 0.867686
ALG10 ALG10, alpha-1,2-glucosyltransferase 0.864734
CHAT choline O-acetyltransferase 0.850845
MECP2 methyl CpG binding protein 2 0.844965
SYP synaptophysin 0.836995
SOD1 superoxide dismutase 1, soluble 0.832385
SCX scleraxis basic helix-loop-helix transcription factor 0.830291
MFGE8 milk fat globule-EGF factor 8 protein 0.829453
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.827778
GFAP glial fibrillary acidic protein 0.826104
EPHB3 EPH receptor B3 0.824431
NTF3 neurotrophin 3 0.817322
TOM1 target of myb1 (chicken) 0.813979
EPHA4 EPH receptor A4 0.810638
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.807716
CALB2 calbindin 2 0.79146
GCH1 GTP cyclohydrolase 1 0.772344
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.766539
EMX2 empty spiracles homeobox 2 0.76157
SPAST spastin 0.753297
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.752884
CHRM1 cholinergic receptor, muscarinic 1 0.749166
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.747102
MAP2 microtubule-associated protein 2 0.744627
TBC1D10A TBC1 domain family, member 10A 0.713369
AIF1 allograft inflammatory factor 1 0.70927
OPTN optineurin 0.706812
FXR2 fragile X mental retardation, autosomal homolog 2 0.703945
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.703945
SKOR1 SKI family transcriptional corepressor 1 0.701489
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.695763
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.694946
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.692493
RPL28 ribosomal protein L28 0.692085
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.684327
DRD2 dopamine receptor D2 0.670064
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.668843
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.657866
NGF nerve growth factor (beta polypeptide) 0.652994
SLC7A4 solute carrier family 7, member 4 0.647316
CBS cystathionine-beta-synthase 0.64529
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.642858
CNTNAP2 contactin associated protein-like 2 0.635167
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.634358
TAGLN3 transgelin 3 0.631527
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.62991
LMNB1 lamin B1 0.626677
DCX doublecortin 0.625869
ATXN3 ataxin 3 0.624658
BTBD9 BTB (POZ) domain containing 9 0.621831
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.621024
CTXN3 cortexin 3 0.620217
HTT huntingtin 0.6182
THAP1 THAP domain containing, apoptosis associated protein 1 0.61175
TBR1 T-box, brain, 1 0.608527
CTNS cystinosin, lysosomal cystine transporter 0.607722
IPO8 importin 8 0.605709
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.596862
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.595255
COPS2 COP9 signalosome subunit 2 0.595255
MBD1 methyl-CpG binding domain protein 1 0.592444
GRM2 glutamate receptor, metabotropic 2 0.588832
PHF1 PHD finger protein 1 0.588431
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.586026
BCHE butyrylcholinesterase 0.583621
UBA2 ubiquitin-like modifier activating enzyme 2 0.582019
MPZL1 myelin protein zero-like 1 0.580017
PINK1 PTEN induced putative kinase 1 0.577215
WDR20 WD repeat domain 20 0.574017
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.572818
KIFC3 kinesin family member C3 0.572418
HNMT histamine N-methyltransferase 0.572018
MUT methylmalonyl CoA mutase 0.569222
ANKK1 ankyrin repeat and kinase domain containing 1 0.56603
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.56603
SGCE sarcoglycan, epsilon 0.563238
OPN3 opsin 3 0.562441
RTN4R reticulon 4 receptor 0.561644
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.561245
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.560847
CPN1 carboxypeptidase N, polypeptide 1 0.556865
FEZF2 FEZ family zinc finger 2 0.555274
PAPOLB poly(A) polymerase beta (testis specific) 0.554876
OTOR otoraplin 0.55249
HIF3A hypoxia inducible factor 3, alpha subunit 0.547326
GLG1 golgi glycoprotein 1 0.535833
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.531879
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.531089
REEP1 receptor accessory protein 1 0.530298
KLK4 kallikrein-related peptidase 4 0.528719
SAE1 SUMO1 activating enzyme subunit 1 0.528719
MLXIPL MLX interacting protein-like 0.527534
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.52635
CGA glycoprotein hormones, alpha polypeptide 0.521617
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.520435
AMH anti-Mullerian hormone 0.516497
CPM carboxypeptidase M 0.516104
KIF3A kinesin family member 3A 0.51453
PDE8B phosphodiesterase 8B 0.514136
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.506672
NES nestin 0.504318
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.501965
LRPPRC leucine-rich pentatricopeptide repeat containing 0.500398
MT1B metallothionein 1B 0.499223
GAP43 growth associated protein 43 0.495309
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.4914
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.490229
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.482428
CBLN2 cerebellin 2 precursor 0.477756
CNTF ciliary neurotrophic factor 0.471151
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.466885
NVL nuclear VCP-like 0.465723
CNR1 cannabinoid receptor 1 (brain) 0.463787
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.459532
MAP2K5 mitogen-activated protein kinase kinase 5 0.459145
LCOR ligand dependent nuclear receptor corepressor 0.456442
SYN1 synapsin I 0.449116
CPT1C carnitine palmitoyltransferase 1C 0.447576
SATB2 SATB homeobox 2 0.443731
SST somatostatin 0.442194
EMX1 empty spiracles homeobox 1 0.441426
MTX2 metaxin 2 0.439507
NOP56 NOP56 ribonucleoprotein 0.437589
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.437589
TGOLN2 trans-golgi network protein 2 0.436822
EGR1 early growth response 1 0.436438
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.436055
FFAR1 free fatty acid receptor 1 0.430695
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.426872
NAIP NLR family, apoptosis inhibitory protein 0.425344
CROCC ciliary rootlet coiled-coil, rootletin 0.424963
PCDH17 protocadherin 17 0.423818
CIC capicua transcriptional repressor 0.415434
HSPA1B heat shock 70kDa protein 1B 0.413912
STMN2 stathmin 2 0.409351
MAOA monoamine oxidase A 0.406315
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.404797
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.404039
LSM1 LSM1, U6 small nuclear RNA associated 0.402901
NMS neuromedin S 0.400628
SDF4 stromal cell derived factor 4 0.399114
CA4 carbonic anhydrase IV 0.395331
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.392686
CALY calcyon neuron-specific vesicular protein 0.387404
CST3 cystatin C 0.379123
CHMP2B charged multivesicular body protein 2B 0.37687
NEFL neurofilament, light polypeptide 0.375743
BMP2K BMP2 inducible kinase 0.375368
FGF2 fibroblast growth factor 2 (basic) 0.374243
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.373118
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.371619
CRBN cereblon 0.368624
KARS lysyl-tRNA synthetase 0.366007
KIF5A kinesin family member 5A 0.36526
PRAC1 prostate cancer susceptibility candidate 1 0.363766
COMT catechol-O-methyltransferase 0.363393
SP6 Sp6 transcription factor 0.354084
MAPK13 mitogen-activated protein kinase 13 0.352598
NEUROD6 neuronal differentiation 6 0.350372
PPT2 palmitoyl-protein thioesterase 2 0.34963
LACTB lactamase, beta 0.345188
SETX senataxin 0.342602
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.341863
CHN1 chimerin 1 0.340757
PCLO piccolo presynaptic cytomatrix protein 0.33744
APOE apolipoprotein E 0.33744
PANK1 pantothenate kinase 1 0.335968
TAC1 tachykinin, precursor 1 0.335233
WWC1 WW and C2 domain containing 1 0.335233
CFL1 cofilin 1 (non-muscle) 0.333763
DRD4 dopamine receptor D4 0.332661
FIG4 FIG4 phosphoinositide 5-phosphatase 0.329727
NARS asparaginyl-tRNA synthetase 0.328994
CSTB cystatin B (stefin B) 0.328994
MBP myelin basic protein 0.328262
PDYN prodynorphin 0.328262
EFHD1 EF-hand domain family, member D1 0.327896
USO1 USO1 vesicle transport factor 0.32497
SPTA1 spectrin, alpha, erythrocytic 1 0.323509
PTMS parathymosin 0.323509
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.315861
IRX2 iroquois homeobox 2 0.314772
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.312957
ANG angiogenin, ribonuclease, RNase A family, 5 0.312595
TAS1R1 taste receptor, type 1, member 1 0.31187
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.311507
MAPK14 mitogen-activated protein kinase 14 0.311507
DCTN1 dynactin 1 0.310059
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.309335
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.307167
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.307167
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.306805
SLC25A27 solute carrier family 25, member 27 0.29996
SPG11 spastic paraplegia 11 (autosomal recessive) 0.298883
HSPA4 heat shock 70kDa protein 4 0.296013
PLXNA4 plexin A4 0.291365
MAOB monoamine oxidase B 0.287803
KLHL17 kelch-like family member 17 0.286736
RICTOR RPTOR independent companion of MTOR, complex 2 0.285316
PRSS21 protease, serine, 21 (testisin) 0.28107
GDF7 growth differentiation factor 7 0.280012
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.278955
INS insulin 0.2779
PRND prion protein 2 (dublet) 0.277197
PRSS3 protease, serine, 3 0.270214
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.269521
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.269174
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.268482
MAG myelin associated glycoprotein 0.268482
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.267791
DEDD death effector domain containing 0.267102
CD68 CD68 molecule 0.265381
AURKC aurora kinase C 0.264696
LIN7A lin-7 homolog A (C. elegans) 0.264011
ERP29 endoplasmic reticulum protein 29 0.262986
INA internexin neuronal intermediate filament protein, alpha 0.262304
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.261624
TPT1 tumor protein, translationally-controlled 1 0.261284
CRMP1 collapsin response mediator protein 1 0.260267
C1QB complement component 1, q subcomponent, B chain 0.259929
RGS7 regulator of G-protein signaling 7 0.257237
GDNF glial cell derived neurotrophic factor 0.256568
FRMD6 FERM domain containing 6 0.256568
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.253578
KIF1B kinesin family member 1B 0.253248
RPLP0 ribosomal protein, large, P0 0.252919
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.250627
LEP leptin 0.248683
CHRM4 cholinergic receptor, muscarinic 4 0.244232
CPSF3L cleavage and polyadenylation specific factor 3-like 0.243605
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.239913
FABP3 fatty acid binding protein 3, muscle and heart 0.23961
HIP1 huntingtin interacting protein 1 0.235167
GLP2R glucagon-like peptide 2 receptor 0.23011
CNTN1 contactin 1 0.229032
BAX BCL2-associated X protein 0.228234
LSAMP limbic system-associated membrane protein 0.22797
TCHH trichohyalin 0.227707
KEAP1 kelch-like ECH-associated protein 1 0.226155
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.224893
JUN jun proto-oncogene 0.224893
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.223662
CD9 CD9 molecule 0.223419
PLP1 proteolipid protein 1 0.221755
IARS isoleucyl-tRNA synthetase 0.221061
MARCKS myristoylated alanine-rich protein kinase C substrate 0.220604
CNTN6 contactin 6 0.219485
PSEN1 presenilin 1 0.217346
ALLC allantoicase 0.215928
BHLHE22 basic helix-loop-helix family, member e22 0.215534
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.214954
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.214576
HSPA1A heat shock 70kDa protein 1A 0.214388
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.21365