motile cilium Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles. (Gene Ontology, GO_0031514)
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Genes

215 proteins localized to the motile cilium cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DNAH11 dynein, axonemal, heavy chain 11 0.663342
UNC119B unc-119 homolog B (C. elegans) 0.663342
UMOD uromodulin 0.663342
CCSAP centriole, cilia and spindle-associated protein 0.663342
SPTBN5 spectrin, beta, non-erythrocytic 5 0.663342
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.663342
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.663342
TPGS1 tubulin polyglutamylase complex subunit 1 0.663342
TMEM67 transmembrane protein 67 0.663342
IFT140 intraflagellar transport 140 0.663342
AKAP4 A kinase (PRKA) anchor protein 4 0.663342
B9D1 B9 protein domain 1 0.663342
TMEM237 transmembrane protein 237 0.663342
PARD3 par-3 family cell polarity regulator 0.663342
ODF2 outer dense fiber of sperm tails 2 0.663342
TAS2R30 taste receptor, type 2, member 30 0.663342
TCTEX1D4 Tctex1 domain containing 4 0.663342
CFAP20 cilia and flagella associated protein 20 0.663342
CEP41 centrosomal protein 41kDa 0.663342
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 0.663342
TTC8 tetratricopeptide repeat domain 8 0.663342
MKS1 Meckel syndrome, type 1 0.663342
RHO rhodopsin 0.663342
RPGR retinitis pigmentosa GTPase regulator 0.663342
TTLL6 tubulin tyrosine ligase-like family member 6 0.663342
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.663342
OXCT2 3-oxoacid CoA transferase 2 0.663342
DNAH9 dynein, axonemal, heavy chain 9 0.663342
DNAH5 dynein, axonemal, heavy chain 5 0.663342
C5ORF30 chromosome 5 open reading frame 30 0.663342
FAM161A family with sequence similarity 161, member A 0.663342
CEP19 centrosomal protein 19kDa 0.663342
OFD1 oral-facial-digital syndrome 1 0.663342
DNAI1 dynein, axonemal, intermediate chain 1 0.663342
RPGRIP1L RPGRIP1-like 0.663342
BBS7 Bardet-Biedl syndrome 7 0.663342
NPHP1 nephronophthisis 1 (juvenile) 0.663342
B9D2 B9 protein domain 2 0.663342
POC1A POC1 centriolar protein A 0.663342
POC1B POC1 centriolar protein B 0.663342
KIAA0586 KIAA0586 0.663342
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.663342
SEPT12 septin 12 0.663342
TBC1D7 TBC1 domain family, member 7 0.663342
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.663342
TBC1D30 TBC1 domain family, member 30 0.663342
RTTN rotatin 0.663342
ROPN1B rhophilin associated tail protein 1B 0.663342
ARL6 ADP-ribosylation factor-like 6 0.663342
AHI1 Abelson helper integration site 1 0.663342
BBS9 Bardet-Biedl syndrome 9 0.663342
TEKT1 tektin 1 0.663342
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.663342
BBS2 Bardet-Biedl syndrome 2 0.663342
TEKT2 tektin 2 (testicular) 0.663342
BBS1 Bardet-Biedl syndrome 1 0.663342
TMEM216 transmembrane protein 216 0.237908
DZIP1L DAZ interacting zinc finger protein 1-like 0.237908
WDR34 WD repeat domain 34 0.237908
GUCA1C guanylate cyclase activator 1C 0.237908
SPA17 sperm autoantigenic protein 17 0.237908
GUCA1A guanylate cyclase activator 1A (retina) 0.237908
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.237908
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.237908
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.237908
RSG1 REM2 and RAB-like small GTPase 1 0.237908
ROPN1L rhophilin associated tail protein 1-like 0.237908
WDR35 WD repeat domain 35 0.237908
PROM1 prominin 1 0.237908
GUCA1B guanylate cyclase activator 1B (retina) 0.237908
RAB3IP RAB3A interacting protein 0.237908
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.237908
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.237908
BBS4 Bardet-Biedl syndrome 4 0.237908
CEP290 centrosomal protein 290kDa 0.237908
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.237908
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 0.237908
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.237908
PGAM4 phosphoglycerate mutase family member 4 0.237908
CROCC ciliary rootlet coiled-coil, rootletin 0.237908
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.237908
SEPT2 septin 2 0.237908
GAS8 growth arrest-specific 8 0.237908
CATSPERD catsper channel auxiliary subunit delta 0.237908
TMEM231 transmembrane protein 231 0.237908
GUCY2F guanylate cyclase 2F, retinal 0.237908
CC2D2A coiled-coil and C2 domain containing 2A 0.237908
TMEM17 transmembrane protein 17 0.237908
FOPNL FGFR1OP N-terminal like 0.237908
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.237908
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 0.237908
CABS1 calcium-binding protein, spermatid-specific 1 0.237908
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.237908
TTBK2 tau tubulin kinase 2 0.237908
WDR19 WD repeat domain 19 0.237908
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.237908
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.237908
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.237908
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.237908
RAB28 RAB28, member RAS oncogene family 0.237908
EVC Ellis van Creveld protein 0.237908
ARL13B ADP-ribosylation factor-like 13B 0.237908
CCDC176 coiled-coil domain containing 176 0.237908
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.237908
PIFO primary cilia formation 0.237908
GRK1 G protein-coupled receptor kinase 1 0.237908
TCTN1 tectonic family member 1 0.237908
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 0.237908
IFT57 intraflagellar transport 57 0.237908
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.237908
SORD sorbitol dehydrogenase 0.237908
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.237908
DZIP1 DAZ interacting zinc finger protein 1 0.237908
TSSK1B testis-specific serine kinase 1B 0.237908
TCTN2 tectonic family member 2 0.237908
IFT88 intraflagellar transport 88 0.237908
CCDC103 coiled-coil domain containing 103 0.098109
IFT81 intraflagellar transport 81 0.098109
DRC7 dynein regulatory complex subunit 7 0.098109
SPAG16 sperm associated antigen 16 0.098109
IFT27 intraflagellar transport 27 0.098109
IFT74 intraflagellar transport 74 0.098109
SPEF1 sperm flagellar 1 0.098109
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.098109
TEKT3 tektin 3 0.098109
BBS5 Bardet-Biedl syndrome 5 0.098109
IFT46 intraflagellar transport 46 0.098109
SPAG4 sperm associated antigen 4 0.098109
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 0.098109
IFT52 intraflagellar transport 52 0.098109
CATSPER3 cation channel, sperm associated 3 0.098109
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.098109
CATSPER1 cation channel, sperm associated 1 0.098109
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.098109
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 0.098109
ENKUR enkurin, TRPC channel interacting protein 0.098109
TEKT4 tektin 4 0.098109
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 0.098109
CATSPER2 cation channel, sperm associated 2 0.098109
SPAG6 sperm associated antigen 6 0.098109
IFT172 intraflagellar transport 172 0.098109
PSEN2 presenilin 2 0.098109
PSEN1 presenilin 1 0.098109
MKKS McKusick-Kaufman syndrome 0.098109
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.098109
EPS15 epidermal growth factor receptor pathway substrate 15 0.03318
CBY1 chibby homolog 1 (Drosophila) 0.03318
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.03318
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.03318
ACTL7A actin-like 7A 0.03318
CATSPERG catsper channel auxiliary subunit gamma 0.03318
KCTD10 potassium channel tetramerization domain containing 10 0.03318
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 0.03318
CATSPER4 cation channel, sperm associated 4 0.03318
IRS1 insulin receptor substrate 1 0.03318
KLC2 kinesin light chain 2 0.03318
KLC3 kinesin light chain 3 0.03318
MNS1 meiosis-specific nuclear structural 1 0.03318
GLIPR1L1 GLI pathogenesis-related 1 like 1 0.03318
C2CD3 C2 calcium-dependent domain containing 3 0.03318
TSPEAR thrombospondin-type laminin G domain and EAR repeats 0.03318
TTC26 tetratricopeptide repeat domain 26 0.03318
PCNT pericentrin 0.03318
PACRG PARK2 co-regulated 0.03318
IQUB IQ motif and ubiquitin domain containing 0.03318
RNF38 ring finger protein 38 0.03318
KIF5B kinesin family member 5B 0.03318
LDHC lactate dehydrogenase C 0.03318
IFT122 intraflagellar transport 122 0.03318
TUBG1 tubulin, gamma 1 0.03318
CNGA3 cyclic nucleotide gated channel alpha 3 0.03318
CNGA1 cyclic nucleotide gated channel alpha 1 0.03318
SMO smoothened, frizzled class receptor 0.03318
PTCHD3 patched domain containing 3 0.03318
EZR ezrin 0.03318
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 0.03318
ROM1 retinal outer segment membrane protein 1 0.03318
SPEF2 sperm flagellar 2 0.03318
PGK2 phosphoglycerate kinase 2 0.03318
AK1 adenylate kinase 1 0.03318
LDHA lactate dehydrogenase A 0.03318
FSCB fibrous sheath CABYR binding protein 0.03318
CDHR1 cadherin-related family member 1 0.03318
KNCN kinocilin 0.03318
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.03318
SEPT4 septin 4 0.03318
NME5 NME/NM23 family member 5 0.03318
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 0.03318
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 0.03318
NME7 NME/NM23 family member 7 0.03318
APP amyloid beta (A4) precursor protein 0.03318
TSGA10 testis specific, 10 0.03318
GSTM3 glutathione S-transferase mu 3 (brain) 0.03318
AK2 adenylate kinase 2 0.03318
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.03318
AKAP3 A kinase (PRKA) anchor protein 3 0.03318
AKAP9 A kinase (PRKA) anchor protein 9 0.03318
PRPH peripherin 0.03318
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.03318
PCM1 pericentriolar material 1 0.03318
RAB8A RAB8A, member RAS oncogene family 0.03318
IFT20 intraflagellar transport 20 0.03318
OAZ3 ornithine decarboxylase antizyme 3 0.03318
RAB8B RAB8B, member RAS oncogene family 0.03318
SSTR3 somatostatin receptor 3 0.03318
CLTB clathrin, light chain B 0.03318
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.03318
DRD2 dopamine receptor D2 0.03318
ODF4 outer dense fiber of sperm tails 4 0.03318
PFKM phosphofructokinase, muscle 0.03318
SPAG17 sperm associated antigen 17 0.03318
DISC1 disrupted in schizophrenia 1 0.03318
CETN2 centrin, EF-hand protein, 2 0.03318
CETN3 centrin, EF-hand protein, 3 0.03318
SLIRP SRA stem-loop interacting RNA binding protein 0.03318