moroxydine-6705 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the moroxydine-6705 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADGB androglobin
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADRA1A adrenoceptor alpha 1A
AIM2 absent in melanoma 2
ALOX5 arachidonate 5-lipoxygenase
ANK1 ankyrin 1, erythrocytic
APOC4 apolipoprotein C-IV
ARHGAP44 Rho GTPase activating protein 44
ASCL1 achaete-scute family bHLH transcription factor 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATN1 atrophin 1
C9ORF9 chromosome 9 open reading frame 9
CCDC57 coiled-coil domain containing 57
CCDC81 coiled-coil domain containing 81
CHMP6 charged multivesicular body protein 6
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CPN2 carboxypeptidase N, polypeptide 2
CRMP1 collapsin response mediator protein 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTRL chymotrypsin-like
CXCR6 chemokine (C-X-C motif) receptor 6
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DSCAM Down syndrome cell adhesion molecule
DTNB dystrobrevin, beta
DZIP1 DAZ interacting zinc finger protein 1
E2F4 E2F transcription factor 4, p107/p130-binding
EGR2 early growth response 2
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FMO5 flavin containing monooxygenase 5
GJA4 gap junction protein, alpha 4, 37kDa
GLB1L2 galactosidase, beta 1-like 2
GLP1R glucagon-like peptide 1 receptor
GPR1 G protein-coupled receptor 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GSN-AS1 GSN antisense RNA 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H4A histone cluster 1, H4a
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMHB1 histocompatibility (minor) HB-1
HPCA hippocalcin
HR hair growth associated
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IFFO1 intermediate filament family orphan 1
IGFBP7 insulin-like growth factor binding protein 7
KIAA1467 KIAA1467
KRT24 keratin 24, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LECT2 leukocyte cell-derived chemotaxin 2
LRMP lymphoid-restricted membrane protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NR2E3 nuclear receptor subfamily 2, group E, member 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAOX polyamine oxidase (exo-N4-amino)
PAX2 paired box 2
PAX8 paired box 8
PCDHA5 protocadherin alpha 5
PDIA2 protein disulfide isomerase family A, member 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCL2 phospholipase C-like 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
POU4F1 POU class 4 homeobox 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS50 protease, serine, 50
PTCH2 patched 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RBBP9 retinoblastoma binding protein 9
RGS12 regulator of G-protein signaling 12
RPL35A ribosomal protein L35a
RPS3A ribosomal protein S3A
RS1 retinoschisin 1
RUNDC3A RUN domain containing 3A
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
STK17A serine/threonine kinase 17a
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD12 tudor domain containing 12
TGFB1 transforming growth factor, beta 1
TMPRSS4 transmembrane protease, serine 4
TRIM14 tripartite motif containing 14
TSC22D3 TSC22 domain family, member 3
UBE2I ubiquitin-conjugating enzyme E2I
VNN2 vanin 2
ZBTB20 zinc finger and BTB domain containing 20
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF268 zinc finger protein 268
ZNF783 zinc finger family member 783
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOL6 apolipoprotein L, 6
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARF5 ADP-ribosylation factor 5
BAHD1 bromo adjacent homology domain containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C1RL complement component 1, r subcomponent-like
C5ORF30 chromosome 5 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
CA5B carbonic anhydrase VB, mitochondrial
CCP110 centriolar coiled coil protein 110kDa
CDC37L1 cell division cycle 37-like 1
CDT1 chromatin licensing and DNA replication factor 1
CHM choroideremia (Rab escort protein 1)
CHRDL1 chordin-like 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN6 chloride channel, voltage-sensitive 6
CLDND1 claudin domain containing 1
CNN2 calponin 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRELD1 cysteine-rich with EGF-like domains 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIXDC1 DIX domain containing 1
EPPK1 epiplakin 1
FOXA1 forkhead box A1
FUZ fuzzy planar cell polarity protein
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
HIST1H3A histone cluster 1, H3a
HOXA4 homeobox A4
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IGSF3 immunoglobulin superfamily, member 3
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
KLF3 Kruppel-like factor 3 (basic)
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
MAPK12 mitogen-activated protein kinase 12
MAPK3 mitogen-activated protein kinase 3
MED15 mediator complex subunit 15
METTL16 methyltransferase like 16
MOB3B MOB kinase activator 3B
MON1B MON1 secretory trafficking family member B
MTA2 metastasis associated 1 family, member 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NABP2 nucleic acid binding protein 2
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPFFR1 neuropeptide FF receptor 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PARP16 poly (ADP-ribose) polymerase family, member 16
PAX9 paired box 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGPEP1 pyroglutamyl-peptidase I
PLCD1 phospholipase C, delta 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR4 proline rich 4 (lacrimal)
RAB5B RAB5B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAI2 retinoic acid induced 2
RAPSN receptor-associated protein of the synapse
RFWD3 ring finger and WD repeat domain 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCN10A sodium channel, voltage gated, type X alpha subunit
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC35F6 solute carrier family 35, member F6
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD5 StAR-related lipid transfer (START) domain containing 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM121 transmembrane protein 121
USP32 ubiquitin specific peptidase 32
WDR18 WD repeat domain 18
ZBTB6 zinc finger and BTB domain containing 6
ZMAT5 zinc finger, matrin-type 5
ZNF141 zinc finger protein 141
ZNF510 zinc finger protein 510
ZNF667 zinc finger protein 667
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2