mood disorder Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cognitive disorder that involves an excessive, irrational dread of everyday situations. (Human Disease Ontology, DOID_3324)
Similar Terms
Downloads & Tools

Genes

221 genes associated with the disease mood disorder in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.894262
HIST1H2BL histone cluster 1, H2bl 0.774217
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 0.682635
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.63207
NCAN neurocan 0.602429
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.602429
SMIM4 small integral membrane protein 4 0.602429
PBRM1 polybromo 1 0.602429
NT5C2 5'-nucleotidase, cytosolic II 0.602429
PALB2 partner and localizer of BRCA2 0.5306
ARL4P ADP-ribosylation factor-like 4 pseudogene 0.52461
HLA-B major histocompatibility complex, class I, B 0.52461
DGKH diacylglycerol kinase, eta 0.486425
INTS7 integrator complex subunit 7 0.486425
MYO10 myosin X 0.486425
FBLN1 fibulin 1 0.486425
PDE10A phosphodiesterase 10A 0.486425
NEK4 NIMA-related kinase 4 0.449873
UST uronyl-2-sulfotransferase 0.449873
ZSWIM6 zinc finger, SWIM-type containing 6 0.449873
FAM110C family with sequence similarity 110, member C 0.438544
MARK1 MAP/microtubule affinity-regulating kinase 1 0.429338
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.429338
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.414708
MCTP1 multiple C2 domains, transmembrane 1 0.403461
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.403461
WDFY4 WDFY family member 4 0.368757
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.368757
GLT8D1 glycosyltransferase 8 domain containing 1 0.368757
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.368757
C11ORF80 chromosome 11 open reading frame 80 0.368757
USP44 ubiquitin specific peptidase 44 0.345945
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.345945
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.345945
FGF12 fibroblast growth factor 12 0.345945
ITGA11 integrin, alpha 11 0.345945
SNX19 sorting nexin 19 0.345945
POU5F1B POU class 5 homeobox 1B 0.345945
KCTD15 potassium channel tetramerization domain containing 15 0.345945
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.327313
BARHL2 BarH-like homeobox 2 0.327313
FOXD2 forkhead box D2 0.327313
ZNF678 zinc finger protein 678 0.327313
DPYD dihydropyrimidine dehydrogenase 0.311576
PTBP2 polypyrimidine tract binding protein 2 0.311576
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.311576
HLA-A major histocompatibility complex, class I, A 0.311576
DOK5 docking protein 5 0.311576
DTWD1 DTW domain containing 1 0.311576
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.297866
RORA RAR-related orphan receptor A 0.297866
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.285417
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.285417
NEBL nebulette 0.285417
LAMP3 lysosomal-associated membrane protein 3 0.285417
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.285417
GDA guanine deaminase 0.274608
CMKLR1 chemerin chemokine-like receptor 1 0.264872
TLE4 transducin-like enhancer of split 4 0.256228
CDC25B cell division cycle 25B 0.256228
DMTF1 cyclin D binding myb-like transcription factor 1 0.256228
GRM7 glutamate receptor, metabotropic 7 0.256228
CGNL1 cingulin-like 1 0.256228
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.256228
TMEM132C transmembrane protein 132C 0.256228
CTSF cathepsin F 0.256228
GMPR guanosine monophosphate reductase 0.256228
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.256228
IFI44 interferon-induced protein 44 0.256228
HOMER1 homer scaffolding protein 1 0.256228
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.256228
SKAP1 src kinase associated phosphoprotein 1 0.256228
PCLO piccolo presynaptic cytomatrix protein 0.256228
LMAN2L lectin, mannose-binding 2-like 0.197766
GRIK5 glutamate receptor, ionotropic, kainate 5 0.197766
SGOL1 shugoshin-like 1 (S. pombe) 0.197766
GPM6A glycoprotein M6A 0.197766
NFIA nuclear factor I/A 0.197766
DPY19L3 dpy-19-like 3 (C. elegans) 0.197766
TTC39B tetratricopeptide repeat domain 39B 0.197766
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.197766
CHL1 cell adhesion molecule L1-like 0.197766
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.197766
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 0.197766
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.197766
LGALS2 lectin, galactoside-binding, soluble, 2 0.197766
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.197766
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.197766
ISX intestine-specific homeobox 0.197766
TDRD9 tudor domain containing 9 0.197766
CDH18 cadherin 18, type 2 0.197766
LAPTM4A lysosomal protein transmembrane 4 alpha 0.197766
CUX1 cut-like homeobox 1 0.197766
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.197766
SLITRK1 SLIT and NTRK-like family, member 1 0.197766
NDFIP2 Nedd4 family interacting protein 2 0.197766
DMD dystrophin 0.197766
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.197766
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.197766
ZNF490 zinc finger protein 490 0.197766
SLFN12L schlafen family member 12-like 0.197766
KIF18A kinesin family member 18A 0.197766
DNM1P46 dynamin 1 pseudogene 46 0.15771
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.15771
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.15771
NLRC5 NLR family, CARD domain containing 5 0.15771
CPM carboxypeptidase M 0.15771
KIAA1211L KIAA1211-like 0.15771
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.15771
PARD6B par-6 family cell polarity regulator beta 0.15771
C15ORF53 chromosome 15 open reading frame 53 0.15771
NUGGC nuclear GTPase, germinal center associated 0.15771
IL11 interleukin 11 0.15771
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.15771
KCNIP4 Kv channel interacting protein 4 0.15771
FOXO6 forkhead box O6 0.15771
MSRA methionine sulfoxide reductase A 0.15771
RASIP1 Ras interacting protein 1 0.15771
ANKRD50 ankyrin repeat domain 50 0.15771
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.15771
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 0.15771
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.15771
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.15771
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.15771
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.15771
PARD3 par-3 family cell polarity regulator 0.15771
RFPL4A ret finger protein-like 4A 0.15771
ZDHHC14 zinc finger, DHHC-type containing 14 0.15771
EIF3F eukaryotic translation initiation factor 3, subunit F 0.15771
GPR65 G protein-coupled receptor 65 0.126165
DMRT1 doublesex and mab-3 related transcription factor 1 0.126165
KIAA1549L KIAA1549-like 0.126165
FGR FGR proto-oncogene, Src family tyrosine kinase 0.126165
NOL4 nucleolar protein 4 0.126165
BRWD1 bromodomain and WD repeat domain containing 1 0.126165
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.126165
SYNE1 spectrin repeat containing, nuclear envelope 1 0.126165
PTPRG protein tyrosine phosphatase, receptor type, G 0.126165
SPRED1 sprouty-related, EVH1 domain containing 1 0.126165
PRSS3 protease, serine, 3 0.126165
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.126165
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.126165
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.126165
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 0.126165
CCNH cyclin H 0.126165
TENM4 teneurin transmembrane protein 4 0.126165
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.126165
KCNU1 potassium channel, subfamily U, member 1 0.126165
NRSN1 neurensin 1 0.126165
AUTS2 autism susceptibility candidate 2 0.100789
FAM189A2 family with sequence similarity 189, member A2 0.100789
GALM galactose mutarotase (aldose 1-epimerase) 0.100789
PCDH1 protocadherin 1 0.100789
C3ORF70 chromosome 3 open reading frame 70 0.100789
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.100789
LINC00596 long intergenic non-protein coding RNA 596 0.100789
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.100789
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.100789
CDH13 cadherin 13 0.100789
NPAS3 neuronal PAS domain protein 3 0.100789
DLC1 DLC1 Rho GTPase activating protein 0.100789
ZNF385D zinc finger protein 385D 0.100789
PDZD8 PDZ domain containing 8 0.100789
TMEM63C transmembrane protein 63C 0.100789
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.100789
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.100789
GRM8 glutamate receptor, metabotropic 8 0.080593
CCND2 cyclin D2 0.080593
CAPN10 calpain 10 0.080593
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.080593
RPL10AP3 ribosomal protein L10a pseudogene 3 0.080593
RERGL RERG/RAS-like 0.080593
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.080593
OLFM3 olfactomedin 3 0.080593
SP4 Sp4 transcription factor 0.080593
SYT4 synaptotagmin IV 0.080593
ATXN7L2 ataxin 7-like 2 0.080593
OR3A2 olfactory receptor, family 3, subfamily A, member 2 0.080593
SIAE sialic acid acetylesterase 0.080593
C15ORF32 chromosome 15 open reading frame 32 0.080593
GFI1B growth factor independent 1B transcription repressor 0.080593
C10ORF126 chromosome 10 open reading frame 126 0.064973
LY86 lymphocyte antigen 86 0.064973
VCAN versican 0.064973
THOC1 THO complex 1 0.064973
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 0.064973
KIAA0355 KIAA0355 0.064973
SPRY2 sprouty homolog 2 (Drosophila) 0.064973
ABLIM1 actin binding LIM protein 1 0.064973
SUMF1 sulfatase modifying factor 1 0.064973
NMUR2 neuromedin U receptor 2 0.064973
KLHL29 kelch-like family member 29 0.064973
SOD3 superoxide dismutase 3, extracellular 0.064973
FAT4 FAT atypical cadherin 4 0.052255
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.052255
FMN1 formin 1 0.052255
ZMIZ1 zinc finger, MIZ-type containing 1 0.052255
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.052255
KRTDAP keratinocyte differentiation-associated protein 0.052255
LINC01559 long intergenic non-protein coding RNA 1559 0.052255
AK8 adenylate kinase 8 0.052255
WSCD2 WSC domain containing 2 0.052255
COMMD10 COMM domain containing 10 0.052255
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.052255
FAM126A family with sequence similarity 126, member A 0.052255
CD276 CD276 molecule 0.043246
DFNB31 deafness, autosomal recessive 31 0.043246
KLHL1 kelch-like family member 1 0.043246
NGFR nerve growth factor receptor 0.043246
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 0.043246
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.043246
CTSH cathepsin H 0.043246
MRPL14 mitochondrial ribosomal protein L14 0.043246
DNAH11 dynein, axonemal, heavy chain 11 0.043246
SLC45A4 solute carrier family 45, member 4 0.043246
ZDBF2 zinc finger, DBF-type containing 2 0.043246
NLGN1 neuroligin 1 0.043246
CNTN1 contactin 1 0.043246
ESRRG estrogen-related receptor gamma 0.043246
PCBP3 poly(rC) binding protein 3 0.043246
IRG1 immunoresponsive 1 homolog (mouse) 0.035343