monorden-999 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the monorden-999 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACVR1B activin A receptor, type IB
ADCY7 adenylate cyclase 7
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX15 arachidonate 15-lipoxygenase
APP amyloid beta (A4) precursor protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG2 BCL2-associated athanogene 2
BAIAP2 BAI1-associated protein 2
BMP8B bone morphogenetic protein 8b
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C11ORF21 chromosome 11 open reading frame 21
C2ORF27A chromosome 2 open reading frame 27A
CA11 carbonic anhydrase XI
CABIN1 calcineurin binding protein 1
CD53 CD53 molecule
CDC14B cell division cycle 14B
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRM3 cholinergic receptor, muscarinic 3
CLCN5 chloride channel, voltage-sensitive 5
CSRP2 cysteine and glycine-rich protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DIDO1 death inducer-obliterator 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EPHB3 EPH receptor B3
FAM169A family with sequence similarity 169, member A
FAM46C family with sequence similarity 46, member C
FGFR2 fibroblast growth factor receptor 2
FRK fyn-related Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GAMT guanidinoacetate N-methyltransferase
GOLGA2 golgin A2
GOSR2 golgi SNAP receptor complex member 2
GPX2 glutathione peroxidase 2
HFE hemochromatosis
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ITGB5 integrin, beta 5
JAG1 jagged 1
KREMEN2 kringle containing transmembrane protein 2
LDHB lactate dehydrogenase B
LIMCH1 LIM and calponin homology domains 1
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
MFAP3L microfibrillar-associated protein 3-like
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NAP1L2 nucleosome assembly protein 1-like 2
NDRG1 N-myc downstream regulated 1
NEUROD6 neuronal differentiation 6
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OSBPL1A oxysterol binding protein-like 1A
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PBX2 pre-B-cell leukemia homeobox 2
PLA2G3 phospholipase A2, group III
PLAU plasminogen activator, urokinase
PPID peptidylprolyl isomerase D
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTBP3 polypyrimidine tract binding protein 3
QSER1 glutamine and serine rich 1
RBM5 RNA binding motif protein 5
RFPL3 ret finger protein-like 3
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRH retinal pigment epithelium-derived rhodopsin homolog
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAI2 snail family zinc finger 2
SRD5A3 steroid 5 alpha-reductase 3
TROVE2 TROVE domain family, member 2
YTHDC1 YTH domain containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZER1 zyg-11 related, cell cycle regulator
ZFAND5 zinc finger, AN1-type domain 5
ZNF227 zinc finger protein 227
ZNF235 zinc finger protein 235
ZNF329 zinc finger protein 329
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
AEN apoptosis enhancing nuclease
AHR aryl hydrocarbon receptor
ANKRD36B ankyrin repeat domain 36B
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARMC6 armadillo repeat containing 6
ASB9 ankyrin repeat and SOCS box containing 9
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIK BCL2-interacting killer (apoptosis-inducing)
BPHL biphenyl hydrolase-like (serine hydrolase)
CBX4 chromobox homolog 4
CCNO cyclin O
CCNT1 cyclin T1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CTSV cathepsin V
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DPH2 DPH2 homolog (S. cerevisiae)
EAF2 ELL associated factor 2
ELMO3 engulfment and cell motility 3
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FAM65A family with sequence similarity 65, member A
FANCC Fanconi anemia, complementation group C
FBXL4 F-box and leucine-rich repeat protein 4
FJX1 four jointed box 1 (Drosophila)
GAREM GRB2 associated, regulator of MAPK1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GMIP GEM interacting protein
GPR19 G protein-coupled receptor 19
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
INPP5K inositol polyphosphate-5-phosphatase K
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM7A lysine (K)-specific demethylase 7A
KIZ kizuna centrosomal protein
KLF11 Kruppel-like factor 11
KRI1 KRI1 homolog (S. cerevisiae)
LIAS lipoic acid synthetase
LINC00115 long intergenic non-protein coding RNA 115
LMCD1 LIM and cysteine-rich domains 1
LPXN leupaxin
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPLA2P1 lysophospholipase II pseudogene 1
MANBA mannosidase, beta A, lysosomal
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP6D1 MAP6 domain containing 1
MARC1 mitochondrial amidoxime reducing component 1
MTCL1 microtubule crosslinking factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NABP2 nucleic acid binding protein 2
NBEAL2 neurobeachin-like 2
NPY5R neuropeptide Y receptor Y5
PARP16 poly (ADP-ribose) polymerase family, member 16
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDGFRL platelet-derived growth factor receptor-like
PER3 period circadian clock 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKCD protein kinase C, delta
PRMT7 protein arginine methyltransferase 7
PUS1 pseudouridylate synthase 1
PYCRL pyrroline-5-carboxylate reductase-like
RAP1GAP2 RAP1 GTPase activating protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RFTN1 raftlin, lipid raft linker 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF38 ring finger protein 38
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SH2B2 SH2B adaptor protein 2
SHARPIN SHANK-associated RH domain interactor
SLC16A6 solute carrier family 16, member 6
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMAD7 SMAD family member 7
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNORA21 small nucleolar RNA, H/ACA box 21
STK25 serine/threonine kinase 25
SYCP2 synaptonemal complex protein 2
SYTL2 synaptotagmin-like 2
THOP1 thimet oligopeptidase 1
TPRA1 transmembrane protein, adipocyte asscociated 1
USP6NL USP6 N-terminal like
VASP vasodilator-stimulated phosphoprotein
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF365 zinc finger protein 365
ZNF623 zinc finger protein 623
ZNF721 zinc finger protein 721
ZXDC ZXD family zinc finger C