monorden-953 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the monorden-953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADCY7 adenylate cyclase 7
ADM adrenomedullin
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ATXN1 ataxin 1
BAG2 BCL2-associated athanogene 2
BAHD1 bromo adjacent homology domain containing 1
BMP4 bone morphogenetic protein 4
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BST2 bone marrow stromal cell antigen 2
CACYBP calcyclin binding protein
CASP7 caspase 7, apoptosis-related cysteine peptidase
CENPF centromere protein F, 350/400kDa
CES3 carboxylesterase 3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL1A1 collagen, type I, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DIAPH2 diaphanous-related formin 2
DIO2 deiodinase, iodothyronine, type II
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP9 dual specificity phosphatase 9
EDRF1 erythroid differentiation regulatory factor 1
EIF1 eukaryotic translation initiation factor 1
EPHA5 EPH receptor A5
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
FGFR1OP FGFR1 oncogene partner
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAL galanin/GMAP prepropeptide
GPX2 glutathione peroxidase 2
GRB10 growth factor receptor-bound protein 10
HFE hemochromatosis
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INHBE inhibin, beta E
ITFG2 integrin alpha FG-GAP repeat containing 2
JAK2 Janus kinase 2
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LPIN1 lipin 1
MAP1B microtubule-associated protein 1B
MAPK13 mitogen-activated protein kinase 13
MED6 mediator complex subunit 6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
N4BP2L2 NEDD4 binding protein 2-like 2
NAP1L2 nucleosome assembly protein 1-like 2
NF2 neurofibromin 2 (merlin)
NMT2 N-myristoyltransferase 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G3 phospholipase A2, group III
POLH polymerase (DNA directed), eta
PTK6 protein tyrosine kinase 6
RPAIN RPA interacting protein
SENP6 SUMO1/sentrin specific peptidase 6
SERBP1 SERPINE1 mRNA binding protein 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGR SH3 domain binding glutamate-rich protein
SIRT5 sirtuin 5
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC1A structural maintenance of chromosomes 1A
SNAI2 snail family zinc finger 2
SNAP23 synaptosomal-associated protein, 23kDa
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SOD2 superoxide dismutase 2, mitochondrial
STK4 serine/threonine kinase 4
TBX19 T-box 19
THBD thrombomodulin
TLE2 transducin-like enhancer of split 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TRIM36 tripartite motif containing 36
TROVE2 TROVE domain family, member 2
UBOX5 U-box domain containing 5
UNKL unkempt family zinc finger-like
USB1 U6 snRNA biogenesis 1
USP48 ubiquitin specific peptidase 48
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33
ZNF227 zinc finger protein 227
ZNF329 zinc finger protein 329
ZNF451 zinc finger protein 451
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AFF4 AF4/FMR2 family, member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD36B ankyrin repeat domain 36B
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASTE1 asteroid homolog 1 (Drosophila)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIK BCL2-interacting killer (apoptosis-inducing)
C10ORF88 chromosome 10 open reading frame 88
C11ORF95 chromosome 11 open reading frame 95
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
C9ORF3 chromosome 9 open reading frame 3
CARD8 caspase recruitment domain family, member 8
CCDC86 coiled-coil domain containing 86
CD302 CD302 molecule
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ECSIT ECSIT signalling integrator
EFHD2 EF-hand domain family, member D2
EGLN2 egl-9 family hypoxia-inducible factor 2
EIF5A2 eukaryotic translation initiation factor 5A2
EPHA2 EPH receptor A2
FAM114A2 family with sequence similarity 114, member A2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GLCE glucuronic acid epimerase
HILPDA hypoxia inducible lipid droplet-associated
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IFT22 intraflagellar transport 22
IPO8 importin 8
IRF2 interferon regulatory factor 2
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
LAMB2 laminin, beta 2 (laminin S)
LARS leucyl-tRNA synthetase
LIN37 lin-37 DREAM MuvB core complex component
LINC00115 long intergenic non-protein coding RNA 115
METTL8 methyltransferase like 8
MOSPD3 motile sperm domain containing 3
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
OGFRL1 opioid growth factor receptor-like 1
PARD6A par-6 family cell polarity regulator alpha
PDGFRL platelet-derived growth factor receptor-like
PGM1 phosphoglucomutase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKCD protein kinase C, delta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB33B RAB33B, member RAS oncogene family
RAD9A RAD9 homolog A (S. pombe)
RBL1 retinoblastoma-like 1
RGS16 regulator of G-protein signaling 16
RGS19 regulator of G-protein signaling 19
RPL23AP7 ribosomal protein L23a pseudogene 7
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SFT2D2 SFT2 domain containing 2
SHROOM2 shroom family member 2
SLC10A3 solute carrier family 10, member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A10 solute carrier family 38, member 10
SMAD7 SMAD family member 7
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
TCTN1 tectonic family member 1
THOP1 thimet oligopeptidase 1
TMEM159 transmembrane protein 159
TOE1 target of EGR1, member 1 (nuclear)
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TXNL4B thioredoxin-like 4B
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
WDR46 WD repeat domain 46
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZFC3H1 zinc finger, C3H1-type containing
ZNF276 zinc finger protein 276
ZNF510 zinc finger protein 510
ZNF721 zinc finger protein 721