monorden-493 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the monorden-493 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ABHD3 abhydrolase domain containing 3
ADAM20 ADAM metallopeptidase domain 20
AFF1 AF4/FMR2 family, member 1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ANAPC2 anaphase promoting complex subunit 2
APOL2 apolipoprotein L, 2
ARHGAP5 Rho GTPase activating protein 5
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARR3 arrestin 3, retinal (X-arrestin)
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAG3 BCL2-associated athanogene 3
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BICD1 bicaudal D homolog 1 (Drosophila)
C11ORF68 chromosome 11 open reading frame 68
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C20ORF27 chromosome 20 open reading frame 27
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CD46 CD46 molecule, complement regulatory protein
CELF2 CUGBP, Elav-like family member 2
CFAP70 cilia and flagella associated protein 70
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
DCLRE1A DNA cross-link repair 1A
DCTN2 dynactin 2 (p50)
DLAT dihydrolipoamide S-acetyltransferase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EGR4 early growth response 4
EIF1 eukaryotic translation initiation factor 1
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC7 exocyst complex component 7
FANCF Fanconi anemia, complementation group F
FBXO11 F-box protein 11
FBXO42 F-box protein 42
FKBP10 FK506 binding protein 10, 65 kDa
GAK cyclin G associated kinase
GAS8 growth arrest-specific 8
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
HDAC2 histone deacetylase 2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HLA-E major histocompatibility complex, class I, E
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IRGQ immunity-related GTPase family, Q
ITM2B integral membrane protein 2B
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCTD7 potassium channel tetramerization domain containing 7
LINC00574 long intergenic non-protein coding RNA 574
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICB MHC class I polypeptide-related sequence B
MOGAT2 monoacylglycerol O-acyltransferase 2
MYL10 myosin, light chain 10, regulatory
NDRG2 NDRG family member 2
NPAT nuclear protein, ataxia-telangiectasia locus
NPR2 natriuretic peptide receptor 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PGF placental growth factor
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PPAN peter pan homolog (Drosophila)
PRB1 proline-rich protein BstNI subfamily 1
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
RBM10 RNA binding motif protein 10
RECQL5 RecQ protein-like 5
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SFXN3 sideroflexin 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SPG20 spastic paraplegia 20 (Troyer syndrome)
SQRDL sulfide quinone reductase-like (yeast)
SRSF5 serine/arginine-rich splicing factor 5
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT5A signal transducer and activator of transcription 5A
TBX3 T-box 3
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TST thiosulfate sulfurtransferase (rhodanese)
TUBA4B tubulin, alpha 4b
UBXN2B UBX domain protein 2B
UFL1 UFM1-specific ligase 1
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
WDR48 WD repeat domain 48
ZMYND8 zinc finger, MYND-type containing 8
ZNF358 zinc finger protein 358
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
AQP2 aquaporin 2 (collecting duct)
AXIN1 axin 1
BAG4 BCL2-associated athanogene 4
BEST1 bestrophin 1
CCP110 centriolar coiled coil protein 110kDa
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDHR2 cadherin-related family member 2
CLCN2 chloride channel, voltage-sensitive 2
CLDN15 claudin 15
CLDN17 claudin 17
COG7 component of oligomeric golgi complex 7
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRNN cornulin
CRYAA crystallin, alpha A
CSN2 casein beta
DCSTAMP dendrocyte expressed seven transmembrane protein
DEFA4 defensin, alpha 4, corticostatin
DENND6B DENN/MADD domain containing 6B
DNASE1L2 deoxyribonuclease I-like 2
EPS8L3 EPS8-like 3
FAM153A family with sequence similarity 153, member A
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF21 fibroblast growth factor 21
FIG4 FIG4 phosphoinositide 5-phosphatase
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FSTL4 follistatin-like 4
GAMT guanidinoacetate N-methyltransferase
GLRA2 glycine receptor, alpha 2
GPR182 G protein-coupled receptor 182
GUCA2A guanylate cyclase activator 2A (guanylin)
HBBP1 hemoglobin, beta pseudogene 1
HCG4B HLA complex group 4B (non-protein coding)
HMBOX1 homeobox containing 1
HOOK2 hook microtubule-tethering protein 2
HOXA3 homeobox A3
HPSE heparanase
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IL2RG interleukin 2 receptor, gamma
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIFC1 kinesin family member C1
KIFC3 kinesin family member C3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLK12 kallikrein-related peptidase 12
LAMA1 laminin, alpha 1
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MPPED1 metallophosphoesterase domain containing 1
MTERF4 mitochondrial transcription termination factor 4
MYBPC3 myosin binding protein C, cardiac
MYL1 myosin, light chain 1, alkali; skeletal, fast
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NOS2 nitric oxide synthase 2, inducible
NPR3 natriuretic peptide receptor 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEK pleckstrin
PPP4C protein phosphatase 4, catalytic subunit
PRAMEF11 PRAME family member 11
PROP1 PROP paired-like homeobox 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB3A RAB3A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RABL6 RAB, member RAS oncogene family-like 6
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SH2D4A SH2 domain containing 4A
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SNX15 sorting nexin 15
SSTR4 somatostatin receptor 4
TBC1D29 TBC1 domain family, member 29
TM4SF5 transmembrane 4 L six family member 5
TMEM176A transmembrane protein 176A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPRA1 transmembrane protein, adipocyte asscociated 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
ULK1 unc-51 like autophagy activating kinase 1
WNT2 wingless-type MMTV integration site family member 2