monorden-325 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the monorden-325 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADAM20 ADAM metallopeptidase domain 20
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANKRD28 ankyrin repeat domain 28
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APP amyloid beta (A4) precursor protein
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAIAP2 BAI1-associated protein 2
BCL7A B-cell CLL/lymphoma 7A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTBD2 BTB (POZ) domain containing 2
C14ORF1 chromosome 14 open reading frame 1
C19ORF66 chromosome 19 open reading frame 66
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C20ORF27 chromosome 20 open reading frame 27
C6ORF47 chromosome 6 open reading frame 47
CACYBP calcyclin binding protein
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDK9 cyclin-dependent kinase 9
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFAP70 cilia and flagella associated protein 70
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CIAO1 cytosolic iron-sulfur assembly component 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLASP1 cytoplasmic linker associated protein 1
DAAM1 dishevelled associated activator of morphogenesis 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
E2F4 E2F transcription factor 4, p107/p130-binding
EID1 EP300 interacting inhibitor of differentiation 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FASTK Fas-activated serine/threonine kinase
FH fumarate hydratase
FKBP8 FK506 binding protein 8, 38kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FXR2 fragile X mental retardation, autosomal homolog 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GSK3A glycogen synthase kinase 3 alpha
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HLA-G major histocompatibility complex, class I, G
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
ITM2B integral membrane protein 2B
ITSN1 intersectin 1 (SH3 domain protein)
KDM4B lysine (K)-specific demethylase 4B
KIF23 kinesin family member 23
L1CAM L1 cell adhesion molecule
LIN7C lin-7 homolog C (C. elegans)
MBOAT7 membrane bound O-acyltransferase domain containing 7
MT1HL1 metallothionein 1H-like 1
NAP1L2 nucleosome assembly protein 1-like 2
NEK1 NIMA-related kinase 1
NNAT neuronatin
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAK1IP1 PAK1 interacting protein 1
PCGF1 polycomb group ring finger 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PISD phosphatidylserine decarboxylase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPID peptidylprolyl isomerase D
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTOV1 prostate tumor overexpressed 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBM28 RNA binding motif protein 28
RCAN1 regulator of calcineurin 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS3 regulator of G-protein signaling 3
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIRT3 sirtuin 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMC2 structural maintenance of chromosomes 2
SP110 SP110 nuclear body protein
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STIP1 stress-induced phosphoprotein 1
SUGP2 SURP and G patch domain containing 2
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D17 TBC1 domain family, member 17
TGM5 transglutaminase 5
TRIO trio Rho guanine nucleotide exchange factor
UBE3A ubiquitin protein ligase E3A
USF2 upstream transcription factor 2, c-fos interacting
VAC14 Vac14 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
YIPF2 Yip1 domain family, member 2
ZIC1 Zic family member 1
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
AMN amnion associated transmembrane protein
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BYSL bystin-like
C8B complement component 8, beta polypeptide
CARTPT CART prepropeptide
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC176 coiled-coil domain containing 176
CCDC71 coiled-coil domain containing 71
CCL11 chemokine (C-C motif) ligand 11
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CDK5 cyclin-dependent kinase 5
CDK5RAP2 CDK5 regulatory subunit associated protein 2
COMMD9 COMM domain containing 9
CP ceruloplasmin (ferroxidase)
CSAD cysteine sulfinic acid decarboxylase
CUZD1 CUB and zona pellucida-like domains 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DAAM2 dishevelled associated activator of morphogenesis 2
DGKD diacylglycerol kinase, delta 130kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DSG3 desmoglein 3
EXOC3 exocyst complex component 3
EXOSC9 exosome component 9
FAR2 fatty acyl CoA reductase 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FMO6P flavin containing monooxygenase 6 pseudogene
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPR3 formyl peptide receptor 3
FSD1 fibronectin type III and SPRY domain containing 1
FXYD6 FXYD domain containing ion transport regulator 6
GLI3 GLI family zinc finger 3
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GPA33 glycoprotein A33 (transmembrane)
GSTA3 glutathione S-transferase alpha 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H3G histone cluster 1, H3g
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTRA2 HtrA serine peptidase 2
IFNA4 interferon, alpha 4
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
LGALS13 lectin, galactoside-binding, soluble, 13
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00216 long intergenic non-protein coding RNA 216
LOC100127972 uncharacterized LOC100127972
LUZP1 leucine zipper protein 1
MCHR1 melanin-concentrating hormone receptor 1
MED31 mediator complex subunit 31
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MMP27 matrix metallopeptidase 27
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYOZ1 myozenin 1
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NCSTN nicastrin
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPY1R neuropeptide Y receptor Y1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OCLM oculomedin
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCD1 phospholipase C, delta 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POU5F1B POU class 5 homeobox 1B
PRDM14 PR domain containing 14
PRKCD protein kinase C, delta
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM4B RNA binding motif protein 4B
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RRAS related RAS viral (r-ras) oncogene homolog
SAG S-antigen; retina and pineal gland (arrestin)
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC24C SEC24 family member C
SH2D2A SH2 domain containing 2A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC35G2 solute carrier family 35, member G2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOX21 SRY (sex determining region Y)-box 21
STAC SH3 and cysteine rich domain
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMPRSS5 transmembrane protease, serine 5
TNS2 tensin 2
TSPO2 translocator protein 2
VIPR1 vasoactive intestinal peptide receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)