monobenzone-6713 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the monobenzone-6713 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAP1 ArfGAP with dual PH domains 1
AFM afamin
ART1 ADP-ribosyltransferase 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1S complement component 1, s subcomponent
C2ORF54 chromosome 2 open reading frame 54
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CALCRL calcitonin receptor-like
CCNE2 cyclin E2
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COMP cartilage oligomeric matrix protein
CRTAC1 cartilage acidic protein 1
CSPG4 chondroitin sulfate proteoglycan 4
CTBP2 C-terminal binding protein 2
CTNND2 catenin (cadherin-associated protein), delta 2
CTSF cathepsin F
CXCR6 chemokine (C-X-C motif) receptor 6
DICER1 dicer 1, ribonuclease type III
DUOX2 dual oxidase 2
EDN3 endothelin 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPB41 erythrocyte membrane protein band 4.1
FABP3 fatty acid binding protein 3, muscle and heart
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GAN gigaxonin
GRIK3 glutamate receptor, ionotropic, kainate 3
GUK1 guanylate kinase 1
HCRTR1 hypocretin (orexin) receptor 1
HEG1 heart development protein with EGF-like domains 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL18R1 interleukin 18 receptor 1
IL22RA1 interleukin 22 receptor, alpha 1
IL33 interleukin 33
INSR insulin receptor
KCTD14 potassium channel tetramerization domain containing 14
KIAA0040 KIAA0040
KIAA0125 KIAA0125
KRT14 keratin 14, type I
MAK male germ cell-associated kinase
MED25 mediator complex subunit 25
MFAP3L microfibrillar-associated protein 3-like
MMP10 matrix metallopeptidase 10
MSX2 msh homeobox 2
MTAP methylthioadenosine phosphorylase
MTCP1 mature T-cell proliferation 1
MTMR7 myotubularin related protein 7
MYBPC3 myosin binding protein C, cardiac
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NPR1 natriuretic peptide receptor 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NTN3 netrin 3
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCDH17 protocadherin 17
PDE4DIP phosphodiesterase 4D interacting protein
PIP prolactin-induced protein
PLXND1 plexin D1
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD51 RAD51 recombinase
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN3 Ras and Rab interactor 3
RNF6 ring finger protein (C3H2C3 type) 6
RPL14 ribosomal protein L14
RPL35A ribosomal protein L35a
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRSF7 serine/arginine-rich splicing factor 7
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBXA2R thromboxane A2 receptor
TCP11L1 t-complex 11, testis-specific-like 1
THPO thrombopoietin
THY1 Thy-1 cell surface antigen
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TSKS testis-specific serine kinase substrate
VWA5A von Willebrand factor A domain containing 5A
WDR78 WD repeat domain 78
ZFP30 ZFP30 zinc finger protein
ZNF428 zinc finger protein 428
ZNF518A zinc finger protein 518A
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BGLAP bone gamma-carboxyglutamate (gla) protein
BORA bora, aurora kinase A activator
C11ORF68 chromosome 11 open reading frame 68
CCNB1 cyclin B1
CCP110 centriolar coiled coil protein 110kDa
CDCA3 cell division cycle associated 3
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CHM choroideremia (Rab escort protein 1)
DBF4B DBF4 zinc finger B
DEPDC1 DEP domain containing 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP3 elongator acetyltransferase complex subunit 3
ELP6 elongator acetyltransferase complex subunit 6
EMP3 epithelial membrane protein 3
EXOC5 exocyst complex component 5
FABP4 fatty acid binding protein 4, adipocyte
FAM64A family with sequence similarity 64, member A
FNTB farnesyltransferase, CAAX box, beta
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR176 G protein-coupled receptor 176
GPX2 glutathione peroxidase 2
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BE histone cluster 1, H2be
HIST1H4C histone cluster 1, H4c
HJURP Holliday junction recognition protein
HP1BP3 heterochromatin protein 1, binding protein 3
IFI6 interferon, alpha-inducible protein 6
KDM7A lysine (K)-specific demethylase 7A
KIAA1456 KIAA1456
KIF14 kinesin family member 14
KIF23 kinesin family member 23
LIMS2 LIM and senescent cell antigen-like domains 2
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK3 mitogen-activated protein kinase 3
MECR mitochondrial trans-2-enoyl-CoA reductase
MITF microphthalmia-associated transcription factor
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
MYL9 myosin, light chain 9, regulatory
NAT6 N-acetyltransferase 6 (GCN5-related)
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPM3 nucleophosmin/nucleoplasmin 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSBP2 oxysterol binding protein 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARPBP PARP1 binding protein
PDCD5 programmed cell death 5
PDE8B phosphodiesterase 8B
PER3 period circadian clock 3
PLK1 polo-like kinase 1
POLM polymerase (DNA directed), mu
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSRC1 proline/serine-rich coiled-coil 1
QSER1 glutamine and serine rich 1
RAB35 RAB35, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF146 ring finger protein 146
RPL11 ribosomal protein L11
RRAGB Ras-related GTP binding B
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SELT selenoprotein T
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAG7 sperm associated antigen 7
SSBP3 single stranded DNA binding protein 3
STK16 serine/threonine kinase 16
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPX2 TPX2, microtubule-associated
TTC4 tetratricopeptide repeat domain 4
UBE2C ubiquitin-conjugating enzyme E2C
USP21 ubiquitin specific peptidase 21
ZBTB6 zinc finger and BTB domain containing 6
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF230 zinc finger protein 230
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF711 zinc finger protein 711