mometasone-2896 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mometasone-2896 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ANG angiogenin, ribonuclease, RNase A family, 5
ARID5A AT rich interactive domain 5A (MRF1-like)
ARTN artemin
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BTG2 BTG family, member 2
C11ORF16 chromosome 11 open reading frame 16
C17ORF59 chromosome 17 open reading frame 59
CCNG2 cyclin G2
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTNS cystinosin, lysosomal cystine transporter
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ERO1LB ERO1-like beta (S. cerevisiae)
EXT1 exostosin glycosyltransferase 1
FAS Fas cell surface death receptor
FKBP14 FK506 binding protein 14, 22 kDa
FLJ11292
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GPR87 G protein-coupled receptor 87
GTPBP2 GTP binding protein 2
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IL21R interleukin 21 receptor
IL32 interleukin 32
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LARP6 La ribonucleoprotein domain family, member 6
LPIN1 lipin 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR22HG MIR22 host gene
MT1F metallothionein 1F
MTUS2 microtubule associated tumor suppressor candidate 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PER1 period circadian clock 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRB3 proline-rich protein BstNI subfamily 3
PRODH proline dehydrogenase (oxidase) 1
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RND1 Rho family GTPase 1
RPL23AP53 ribosomal protein L23a pseudogene 53
SAT1 spermidine/spermine N1-acetyltransferase 1
SERHL2 serine hydrolase-like 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRCAP Snf2-related CREBBP activator protein
STIM1 stromal interaction molecule 1
TLR2 toll-like receptor 2
TMEM63A transmembrane protein 63A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WIPI1 WD repeat domain, phosphoinositide interacting 1
YPEL5 yippee-like 5 (Drosophila)
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ACTL8 actin-like 8
AGMAT agmatine ureohydrolase (agmatinase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C2CD2 C2 calcium-dependent domain containing 2
CARD8 caspase recruitment domain family, member 8
CASP8AP2 caspase 8 associated protein 2
CCDC85C coiled-coil domain containing 85C
CCNE2 cyclin E2
CCNO cyclin O
CD3EAP CD3e molecule, epsilon associated protein
CDC7 cell division cycle 7
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CISH cytokine inducible SH2-containing protein
CSTA cystatin A (stefin A)
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNA2 DNA replication helicase/nuclease 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPPK1 epiplakin 1
EVPL envoplakin
FAM189B family with sequence similarity 189, member B
FBXO5 F-box protein 5
FKBP1B FK506 binding protein 1B, 12.6 kDa
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GLCE glucuronic acid epimerase
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GPX2 glutathione peroxidase 2
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0754 KIAA0754
KIF16B kinesin family member 16B
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT13 keratin 13, type I
LIN7B lin-7 homolog B (C. elegans)
LOC729164 hCG1732469
LOC730101 uncharacterized LOC730101
LPPR1 lipid phosphate phosphatase-related protein type 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MANEA mannosidase, endo-alpha
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MARC1 mitochondrial amidoxime reducing component 1
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
NT5E 5'-nucleotidase, ecto (CD73)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PARPBP PARP1 binding protein
PCDHA6 protocadherin alpha 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTPRU protein tyrosine phosphatase, receptor type, U
RAD51AP1 RAD51 associated protein 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIBC2 RIB43A domain with coiled-coils 2
RPAP1 RNA polymerase II associated protein 1
RPGRIP1L RPGRIP1-like
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SECTM1 secreted and transmembrane 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SUSD4 sushi domain containing 4
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMEM180 transmembrane protein 180
TRIM36 tripartite motif containing 36
TWSG1 twisted gastrulation BMP signaling modulator 1
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR76 WD repeat domain 76
ZDHHC18 zinc finger, DHHC-type containing 18
ZMYM3 zinc finger, MYM-type 3
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551