molindone-7337 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the molindone-7337 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPT1 angiopoietin 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP7 aquaporin 7
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATP9A ATPase, class II, type 9A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C2ORF27A chromosome 2 open reading frame 27A
CD79A CD79a molecule, immunoglobulin-associated alpha
CD82 CD82 molecule
CDC25A cell division cycle 25A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLCN7 chloride channel, voltage-sensitive 7
CLUAP1 clusterin associated protein 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COL1A1 collagen, type I, alpha 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DESI2 desumoylating isopeptidase 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSCAM Down syndrome cell adhesion molecule
DUSP26 dual specificity phosphatase 26 (putative)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHA1 EPH receptor A1
EXO5 exonuclease 5
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FOSL2 FOS-like antigen 2
FRK fyn-related Src family tyrosine kinase
FZD7 frizzled class receptor 7
GAMT guanidinoacetate N-methyltransferase
GLP1R glucagon-like peptide 1 receptor
GOLGA2 golgin A2
HOXB6 homeobox B6
IL22 interleukin 22
IL6ST interleukin 6 signal transducer
KIAA0040 KIAA0040
KIAA0368 KIAA0368
KIAA1109 KIAA1109
KIAA1456 KIAA1456
KIF25 kinesin family member 25
KRT19P2 keratin 19 pseudogene 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LOC257152 uncharacterized LOC257152
LRP12 low density lipoprotein receptor-related protein 12
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAK male germ cell-associated kinase
MAP1A microtubule-associated protein 1A
MAP2K7 mitogen-activated protein kinase kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
MTAP methylthioadenosine phosphorylase
MYOZ1 myozenin 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
OASL 2'-5'-oligoadenylate synthetase-like
PAPPA2 pappalysin 2
PAX5 paired box 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXNA3 plexin A3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRF1 perforin 1 (pore forming protein)
PSAT1 phosphoserine aminotransferase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PXN paxillin
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM26 RNA binding motif protein 26
RGS12 regulator of G-protein signaling 12
RLN1 relaxin 1
RPS2 ribosomal protein S2
RPS4Y1 ribosomal protein S4, Y-linked 1
RSU1 Ras suppressor protein 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRPA signal-regulatory protein alpha
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMTN smoothelin
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNPH syntaphilin
SSPN sarcospan
TBC1D2 TBC1 domain family, member 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM63A transmembrane protein 63A
TNK1 tyrosine kinase, non-receptor, 1
TPSG1 tryptase gamma 1
TRA T cell receptor alpha locus
TREX1 three prime repair exonuclease 1
USP20 ubiquitin specific peptidase 20
VAC14 Vac14 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
VDAC3 voltage-dependent anion channel 3
ZNF500 zinc finger protein 500
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AOX1 aldehyde oxidase 1
APH1B APH1B gamma secretase subunit
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF40 chromosome 19 open reading frame 40
CA11 carbonic anhydrase XI
CAPG capping protein (actin filament), gelsolin-like
CASD1 CAS1 domain containing 1
CBX7 chromobox homolog 7
CCDC85C coiled-coil domain containing 85C
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPJ centromere protein J
CHMP7 charged multivesicular body protein 7
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLASP1 cytoplasmic linker associated protein 1
CNPY3 canopy FGF signaling regulator 3
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNALI1 dynein, axonemal, light intermediate chain 1
DVL1 dishevelled segment polarity protein 1
EXD3 exonuclease 3'-5' domain containing 3
FBXL6 F-box and leucine-rich repeat protein 6
FCHSD2 FCH and double SH3 domains 2
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HIST1H4F histone cluster 1, H4f
HMOX1 heme oxygenase 1
IGSF1 immunoglobulin superfamily, member 1
JUNB jun B proto-oncogene
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
KLHL25 kelch-like family member 25
LAMB3 laminin, beta 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHFPL2 lipoma HMGIC fusion partner-like 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC61 leucine rich repeat containing 61
MATK megakaryocyte-associated tyrosine kinase
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MOSPD3 motile sperm domain containing 3
NFE2L3 nuclear factor, erythroid 2-like 3
NHLRC2 NHL repeat containing 2
NT5DC3 5'-nucleotidase domain containing 3
NUP62CL nucleoporin 62kDa C-terminal like
OSGEP O-sialoglycoprotein endopeptidase
PCSK7 proprotein convertase subtilisin/kexin type 7
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRR14L proline rich 14-like
PUS1 pseudouridylate synthase 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBL1 retinoblastoma-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF31 ring finger protein 31
RPUSD2 RNA pseudouridylate synthase domain containing 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SOWAHC sosondowah ankyrin repeat domain family member C
SPAG4 sperm associated antigen 4
SPINK4 serine peptidase inhibitor, Kazal type 4
SSBP3 single stranded DNA binding protein 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAGLN transgelin
THOC6 THO complex 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRIP10 thyroid hormone receptor interactor 10
TSPAN1 tetraspanin 1
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
YEATS2 YEATS domain containing 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF250 zinc finger protein 250
ZNF432 zinc finger protein 432
ZNF675 zinc finger protein 675
ZNF8 zinc finger protein 8