molindone-4784 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the molindone-4784 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BMP2K BMP2 inducible kinase
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CA1 carbonic anhydrase I
CALD1 caldesmon 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCNE2 cyclin E2
CD6 CD6 molecule
CD8B CD8b molecule
CHKB choline kinase beta
CIDEB cell death-inducing DFFA-like effector b
CLIC2 chloride intracellular channel 2
CRMP1 collapsin response mediator protein 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYLD cylindromatosis (turban tumor syndrome)
DEFA4 defensin, alpha 4, corticostatin
DLC1 DLC1 Rho GTPase activating protein
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EXOC5 exocyst complex component 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP3 fatty acid binding protein 3, muscle and heart
FAS Fas cell surface death receptor
FAXDC2 fatty acid hydroxylase domain containing 2
GPC1 glypican 1
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HOXA6 homeobox A6
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IMPG2 interphotoreceptor matrix proteoglycan 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBOV1 prostate and breast cancer overexpressed 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNC1 plexin C1
PRB1 proline-rich protein BstNI subfamily 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCH protein kinase C, eta
PTCRA pre T-cell antigen receptor alpha
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RAD51B RAD51 paralog B
RBBP9 retinoblastoma binding protein 9
RBM12B-AS1 RBM12B antisense RNA 1
RCAN3 RCAN family member 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
REPS1 RALBP1 associated Eps domain containing 1
RFPL3 ret finger protein-like 3
RNF6 ring finger protein (C3H2C3 type) 6
RYK receptor-like tyrosine kinase
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMAD5 SMAD family member 5
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
STMN1 stathmin 1
TAGLN3 transgelin 3
TARP TCR gamma alternate reading frame protein
TCP10 t-complex 10
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI2 tissue factor pathway inhibitor 2
TMEM212 transmembrane protein 212
TMPRSS4 transmembrane protease, serine 4
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRADD TNFRSF1A-associated via death domain
TSC2 tuberous sclerosis 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VARS valyl-tRNA synthetase
VCAN versican
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR55 WD repeat domain 55
XYLB xylulokinase homolog (H. influenzae)
ZNF304 zinc finger protein 304
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADCY6 adenylate cyclase 6
AHDC1 AT hook, DNA binding motif, containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATXN2 ataxin 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBC3 BCL2 binding component 3
BCR breakpoint cluster region
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CAPG capping protein (actin filament), gelsolin-like
CAPN1 calpain 1, (mu/I) large subunit
CLDN9 claudin 9
CRIP1 cysteine-rich protein 1 (intestinal)
CST6 cystatin E/M
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOC2A double C2-like domains, alpha
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DSCAM Down syndrome cell adhesion molecule
EGLN2 egl-9 family hypoxia-inducible factor 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVPL envoplakin
FAM63A family with sequence similarity 63, member A
FBXO22 F-box protein 22
FGGY FGGY carbohydrate kinase domain containing
FKBP10 FK506 binding protein 10, 65 kDa
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GBP2 guanylate binding protein 2, interferon-inducible
GCHFR GTP cyclohydrolase I feedback regulator
GLB1L2 galactosidase, beta 1-like 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HDAC4 histone deacetylase 4
HIST1H1C histone cluster 1, H1c
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPPL1 inositol polyphosphate phosphatase-like 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0894 KIAA0894 protein
KLC2 kinesin light chain 2
KLF3 Kruppel-like factor 3 (basic)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
LRP5 low density lipoprotein receptor-related protein 5
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED24 mediator complex subunit 24
MITF microphthalmia-associated transcription factor
MOSPD3 motile sperm domain containing 3
NCS1 neuronal calcium sensor 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PELP1 proline, glutamate and leucine rich protein 1
PHACTR4 phosphatase and actin regulator 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PTPRU protein tyrosine phosphatase, receptor type, U
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM10 RNA binding motif protein 10
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A6 S100 calcium binding protein A6
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLIT2 slit homolog 2 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX5 syntaxin 5
STXBP2 syntaxin binding protein 2
SUGP1 SURP and G patch domain containing 1
TCTA T-cell leukemia translocation altered
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TH tyrosine hydroxylase
THEM6 thioesterase superfamily member 6
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM121 transmembrane protein 121
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPO translocator protein (18kDa)
TUBA3D tubulin, alpha 3d
UPP1 uridine phosphorylase 1
VWA1 von Willebrand factor A domain containing 1
WDR19 WD repeat domain 19
ZBED1 zinc finger, BED-type containing 1
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF324 zinc finger protein 324