molindone-2917 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the molindone-2917 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACACB acetyl-CoA carboxylase beta
AIF1 allograft inflammatory factor 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANGPTL2 angiopoietin-like 2
AREG amphiregulin
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC6 armadillo repeat containing 6
ATXN2L ataxin 2-like
BAIAP2 BAI1-associated protein 2
BTN3A1 butyrophilin, subfamily 3, member A1
CA11 carbonic anhydrase XI
CA8 carbonic anhydrase VIII
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAV2 caveolin 2
CCDC40 coiled-coil domain containing 40
CCNJL cyclin J-like
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CECR1 cat eye syndrome chromosome region, candidate 1
CLCN7 chloride channel, voltage-sensitive 7
CLTA clathrin, light chain A
COPE coatomer protein complex, subunit epsilon
CPED1 cadherin-like and PC-esterase domain containing 1
CSDC2 cold shock domain containing C2, RNA binding
CTSF cathepsin F
CXCL11 chemokine (C-X-C motif) ligand 11
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCAF4 DDB1 and CUL4 associated factor 4
DGKQ diacylglycerol kinase, theta 110kDa
DTNB dystrobrevin, beta
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ETV1 ets variant 1
EXTL3 exostosin-like glycosyltransferase 3
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM155A family with sequence similarity 155, member A
FGFR1 fibroblast growth factor receptor 1
FOXC1 forkhead box C1
GLP1R glucagon-like peptide 1 receptor
GP5 glycoprotein V (platelet)
GPATCH4 G patch domain containing 4
GPR153 G protein-coupled receptor 153
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRM7 glutamate receptor, metabotropic 7
GYG2 glycogenin 2
ICAM5 intercellular adhesion molecule 5, telencephalin
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IGLL1 immunoglobulin lambda-like polypeptide 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KLK13 kallikrein-related peptidase 13
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3A mucin 3A, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NEB nebulin
NF2 neurofibromin 2 (merlin)
NLE1 notchless homolog 1 (Drosophila)
NPFFR1 neuropeptide FF receptor 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDLIM5 PDZ and LIM domain 5
PGAP3 post-GPI attachment to proteins 3
PLAC4 placenta-specific 4
PLEC plectin
PRDM11 PR domain containing 11
PTCRA pre T-cell antigen receptor alpha
RAP1GAP RAP1 GTPase activating protein
RAP1GAP2 RAP1 GTPase activating protein 2
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RNF17 ring finger protein 17
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCARB2 scavenger receptor class B, member 2
SELPLG selectin P ligand
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3D21 SH3 domain containing 21
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A2 solute carrier family 17, member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SP140 SP140 nuclear body protein
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST7L suppression of tumorigenicity 7 like
TBKBP1 TBK1 binding protein 1
THAP3 THAP domain containing, apoptosis associated protein 3
THSD7A thrombospondin, type I, domain containing 7A
TNK2 tyrosine kinase, non-receptor, 2
TSC22D2 TSC22 domain family, member 2
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF234 zinc finger protein 234
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAM23 ADAM metallopeptidase domain 23
ADGRE5 adhesion G protein-coupled receptor E5
AOAH acyloxyacyl hydrolase (neutrophil)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARF5 ADP-ribosylation factor 5
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
C10ORF2 chromosome 10 open reading frame 2
C11ORF21 chromosome 11 open reading frame 21
C17ORF80 chromosome 17 open reading frame 80
C3 complement component 3
CD82 CD82 molecule
CLCN6 chloride channel, voltage-sensitive 6
CLEC2D C-type lectin domain family 2, member D
CSNK1G3 casein kinase 1, gamma 3
DEPTOR DEP domain containing MTOR-interacting protein
EDC3 enhancer of mRNA decapping 3
EDC4 enhancer of mRNA decapping 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR2 early growth response 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERI3 ERI1 exoribonuclease family member 3
FAM114A1 family with sequence similarity 114, member A1
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FGL2 fibrinogen-like 2
FMO4 flavin containing monooxygenase 4
FPGS folylpolyglutamate synthase
FZD2 frizzled class receptor 2
GALE UDP-galactose-4-epimerase
GJA1 gap junction protein, alpha 1, 43kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMGB3 high mobility group box 3
HPSE heparanase
IFI30 interferon, gamma-inducible protein 30
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
L2HGDH L-2-hydroxyglutarate dehydrogenase
LNPEP leucyl/cystinyl aminopeptidase
LZTR1 leucine-zipper-like transcription regulator 1
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MFSD11 major facilitator superfamily domain containing 11
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MPST mercaptopyruvate sulfurtransferase
MXD3 MAX dimerization protein 3
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OTUD3 OTU deubiquitinase 3
PGPEP1 pyroglutamyl-peptidase I
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPAN peter pan homolog (Drosophila)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTTG3P pituitary tumor-transforming 3, pseudogene
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFTN1 raftlin, lipid raft linker 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RWDD3 RWD domain containing 3
SCAND1 SCAN domain containing 1
SERINC5 serine incorporator 5
SHPK sedoheptulokinase
SKI SKI proto-oncogene
SLC10A3 solute carrier family 10, member 3
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLFN12 schlafen family member 12
SNHG20 small nucleolar RNA host gene 20
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STRN striatin, calmodulin binding protein
STX1A syntaxin 1A (brain)
THAP10 THAP domain containing 10
TMEM127 transmembrane protein 127
TRABD TraB domain containing
TRAPPC2L trafficking protein particle complex 2-like
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TTI1 TELO2 interacting protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
ZBTB48 zinc finger and BTB domain containing 48
ZMAT3 zinc finger, matrin-type 3
ZNF250 zinc finger protein 250
ZNF468 zinc finger protein 468
ZNF493 zinc finger protein 493
ZNF816 zinc finger protein 816