mixed cell type cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from two germinal layers of tissue. (Human Disease Ontology, DOID_154)
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Genes

198 genes co-occuring with the disease mixed cell type cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 1.42498
KRT7 keratin 7, type II 1.34548
MB myoglobin 1.22475
SYP synaptophysin 1.11856
ERBB2 erb-b2 receptor tyrosine kinase 2 1.10931
FAM175A family with sequence similarity 175, member A 0.97044
ENO2 enolase 2 (gamma, neuronal) 0.961216
AFP alpha-fetoprotein 0.949102
PTHLH parathyroid hormone-like hormone 0.946186
ESR1 estrogen receptor 1 0.939119
PGR progesterone receptor 0.925865
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.918024
KRT20 keratin 20, type I 0.908553
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.876557
GFAP glial fibrillary acidic protein 0.86018
CD34 CD34 molecule 0.853631
MYOG myogenin (myogenic factor 4) 0.851173
CALB2 calbindin 2 0.843392
KRAS Kirsten rat sarcoma viral oncogene homolog 0.827819
HRAS Harvey rat sarcoma viral oncogene homolog 0.813873
KRT14 keratin 14, type I 0.793771
MYCT1 myc target 1 0.788033
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 0.774932
CALD1 caldesmon 1 0.768393
KRT5 keratin 5, type II 0.760639
B3GAT1 beta-1,3-glucuronyltransferase 1 0.754934
ARID1A AT rich interactive domain 1A (SWI-like) 0.752898
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.750864
CGRRF1 cell growth regulator with ring finger domain 1 0.745578
TXNDC17 thioredoxin domain containing 17 0.739894
PLAG1 pleiomorphic adenoma gene 1 0.733406
ACPP acid phosphatase, prostate 0.726524
CTPS2 CTP synthase 2 0.720865
CST11 cystatin 11 0.710378
CAPN6 calpain 6 0.708364
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.699919
PTEN phosphatase and tensin homolog 0.694702
EGFR epidermal growth factor receptor 0.681495
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.679898
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.67551
CHGA chromogranin A 0.648533
HMGA2 high mobility group AT-hook 2 0.645375
MLANA melan-A 0.606543
SS18 synovial sarcoma translocation, chromosome 18 0.597571
MKI67 marker of proliferation Ki-67 0.593285
WT1 Wilms tumor 1 0.586276
MIP major intrinsic protein of lens fiber 0.585497
NCAM1 neural cell adhesion molecule 1 0.573439
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.572662
PIP prolactin-induced protein 0.55945
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.55712
MON1A MON1 secretory trafficking family member A 0.548583
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.547807
MUC20 mucin 20, cell surface associated 0.544318
MYOD1 myogenic differentiation 1 0.540442
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.538118
CD68 CD68 molecule 0.524974
KRT8 keratin 8, type II 0.516494
MIRLET7B microRNA let-7b 0.508424
NKX2-1 NK2 homeobox 1 0.495411
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.494648
RNASEH2A ribonuclease H2, subunit A 0.480945
EWSR1 EWS RNA-binding protein 1 0.472604
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.469954
KRT18 keratin 18, type I 0.455224
DES desmin 0.438658
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.438658
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.437906
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.437906
CDKN2A cyclin-dependent kinase inhibitor 2A 0.436026
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.430393
ALPP alkaline phosphatase, placental 0.430017
ALPPL2 alkaline phosphatase, placental-like 2 0.42814
ALPL alkaline phosphatase, liver/bone/kidney 0.427015
HBA1 hemoglobin, alpha 1 0.414276
CSHL1 chorionic somatomammotropin hormone-like 1 0.413153
MUC6 mucin 6, oligomeric mucus/gel-forming 0.406051
BRCA1 breast cancer 1, early onset 0.402692
CLDN10 claudin 10 0.401199
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.400826
ZNF135 zinc finger protein 135 0.399707
HBA2 hemoglobin, alpha 2 0.392629
MLH1 mutL homolog 1 0.390769
DHFR dihydrofolate reductase 0.389653
PAX8 paired box 8 0.388166
CTPS1 CTP synthase 1 0.383337
BEST2 bestrophin 2 0.382594
ZEB2 zinc finger E-box binding homeobox 2 0.37555
PTH parathyroid hormone 0.375179
SPOP speckle-type POZ protein 0.374809
PCNA proliferating cell nuclear antigen 0.357446
CLEC2A C-type lectin domain family 2, member A 0.339073
CES2 carboxylesterase 2 0.337242
AR androgen receptor 0.331025
SHPK sedoheptulokinase 0.325552
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.324458
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.323365
HMGA1 high mobility group AT-hook 1 0.312827
TG thyroglobulin 0.312102
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.310652
IVL involucrin 0.308842
KLK3 kallikrein-related peptidase 3 0.305226
TCEA1 transcription elongation factor A (SII), 1 0.299092
MSH6 mutS homolog 6 0.298731
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.296211
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.295132
TWIST1 twist family bHLH transcription factor 1 0.294413
DMRTA1 DMRT-like family A1 0.288668
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.285444
CCND1 cyclin D1 0.283297
TNF tumor necrosis factor 0.275801
TFDP3 transcription factor Dp family, member 3 0.273308
ZEB1 zinc finger E-box binding homeobox 1 0.268332
ALB albumin 0.265849
CCK cholecystokinin 0.265494
TWIST2 twist family bHLH transcription factor 2 0.263722
IL2 interleukin 2 0.263368
MSH2 mutS homolog 2 0.262306
ESR2 estrogen receptor 2 (ER beta) 0.260891
ACTA1 actin, alpha 1, skeletal muscle 0.257711
THBS4 thrombospondin 4 0.256652
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.253479
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.242245
MET MET proto-oncogene, receptor tyrosine kinase 0.241546
DKKL1 dickkopf-like 1 0.235616
SEBOX SEBOX homeobox 0.235268
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.234573
NMB neuromedin B 0.233878
ARID1B AT rich interactive domain 1B (SWI1-like) 0.231795
GLS glutaminase 0.231102
AKR1C1 aldo-keto reductase family 1, member C1 0.229024
LIN28B lin-28 homolog B (C. elegans) 0.22454
FN1 fibronectin 1 0.222479
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.218715
CTSE cathepsin E 0.215314
TNC tenascin C 0.213959
VEGFA vascular endothelial growth factor A 0.207245
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.205585
CAT catalase 0.205254
CD99 CD99 molecule 0.201635
ALK anaplastic lymphoma receptor tyrosine kinase 0.194548
AOX1 aldehyde oxidase 1 0.191408
MUC1 mucin 1, cell surface associated 0.190476
POLK polymerase (DNA directed) kappa 0.188938
ACR acrosin 0.187719
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.180084
CPSF3L cleavage and polyadenylation specific factor 3-like 0.177029
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.176757
CTSH cathepsin H 0.174881
CD6 CD6 molecule 0.172291
CALCA calcitonin-related polypeptide alpha 0.169091
SLC22A18 solute carrier family 22, member 18 0.167915
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.164786
CHMP2A charged multivesicular body protein 2A 0.164149
RAD51C RAD51 paralog C 0.163729
ADAR adenosine deaminase, RNA-specific 0.162707
F2R coagulation factor II (thrombin) receptor 0.162707
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.162505
GPC3 glypican 3 0.161912
CYS1 cystin 1 0.161523
KITLG KIT ligand 0.160021
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.144283
MUC2 mucin 2, oligomeric mucus/gel-forming 0.142681
MATN3 matrilin 3 0.140926
FGFR2 fibroblast growth factor receptor 2 0.138331
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.135394
ERBB4 erb-b2 receptor tyrosine kinase 4 0.135252
CD24 CD24 molecule 0.133412
WIPF2 WAS/WASL interacting protein family, member 2 0.132699
MUC4 mucin 4, cell surface associated 0.12962
INHA inhibin, alpha 0.12916
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.128748
HNF1B HNF1 homeobox B 0.127023
DICER1 dicer 1, ribonuclease type III 0.125365
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.12445
GATA4 GATA binding protein 4 0.124406
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.123433
SP1 Sp1 transcription factor 0.122961
BMP2 bone morphogenetic protein 2 0.119274
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.113369
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.113187
F8 coagulation factor VIII, procoagulant component 0.112819
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.112179
AMH anti-Mullerian hormone 0.111836
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.110782
LOXL2 lysyl oxidase-like 2 0.107416
SNAI2 snail family zinc finger 2 0.107156
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.10667
TERT telomerase reverse transcriptase 0.106626
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.106537
MAGEC1 melanoma antigen family C1 0.105685
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.104676
SNAI1 snail family zinc finger 1 0.103926
CD151 CD151 molecule (Raph blood group) 0.10326
BARD1 BRCA1 associated RING domain 1 0.103164
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.103164
BRCA2 breast cancer 2, early onset 0.102828
CSN1S1 casein alpha s1 0.102295