minoxidil-4800 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the minoxidil-4800 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTN2 actinin, alpha 2
ADGB androglobin
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGO4 argonaute RISC catalytic component 4
ANGPTL2 angiopoietin-like 2
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
BLVRA biliverdin reductase A
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF56 chromosome 1 open reading frame 56
C8ORF60 chromosome 8 open reading frame 60
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK17 cyclin-dependent kinase 17
CEP250 centrosomal protein 250kDa
CHD1L chromodomain helicase DNA binding protein 1-like
CSF1R colony stimulating factor 1 receptor
CSNK1A1 casein kinase 1, alpha 1
CSNK1G1 casein kinase 1, gamma 1
CSTA cystatin A (stefin A)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYB5R2 cytochrome b5 reductase 2
DBN1 drebrin 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DPP4 dipeptidyl-peptidase 4
ESR1 estrogen receptor 1
EXOC5 exocyst complex component 5
FAS Fas cell surface death receptor
FBXL7 F-box and leucine-rich repeat protein 7
FCMR Fc fragment of IgM receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FH fumarate hydratase
FRMD4B FERM domain containing 4B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB3 gap junction protein, beta 3, 31kDa
GTF2I general transcription factor IIi
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HMGN5 high mobility group nucleosome binding domain 5
HOXC5 homeobox C5
HSPA12A heat shock 70kDa protein 12A
ITGA10 integrin, alpha 10
KLF4 Kruppel-like factor 4 (gut)
KRT83 keratin 83, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LIN7A lin-7 homolog A (C. elegans)
LPL lipoprotein lipase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK11 mitogen-activated protein kinase 11
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEGF6 multiple EGF-like-domains 6
MTM1 myotubularin 1
NEU2 sialidase 2 (cytosolic sialidase)
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOTCH2 notch 2
NXT2 nuclear transport factor 2-like export factor 2
PARD6B par-6 family cell polarity regulator beta
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM3 PDZ and LIM domain 3
PICALM phosphatidylinositol binding clathrin assembly protein
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PRDM14 PR domain containing 14
PSD3 pleckstrin and Sec7 domain containing 3
PTCH2 patched 2
PXN paxillin
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD51 RAD51 recombinase
RARG retinoic acid receptor, gamma
RNF146 ring finger protein 146
RPGR retinitis pigmentosa GTPase regulator
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMAD5 SMAD family member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPAG6 sperm associated antigen 6
SQLE squalene epoxidase
SSBP2 single-stranded DNA binding protein 2
STOM stomatin
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBL2 transducin (beta)-like 2
TFDP1 transcription factor Dp-1
THBS3 thrombospondin 3
TMPRSS15 transmembrane protease, serine 15
TMPRSS2 transmembrane protease, serine 2
TOX4 TOX high mobility group box family member 4
TPMT thiopurine S-methyltransferase
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIB2 tribbles pseudokinase 2
TRIP11 thyroid hormone receptor interactor 11
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H13 zinc finger CCCH-type containing 13
ZNF516 zinc finger protein 516

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
AMPD2 adenosine monophosphate deaminase 2
APOLD1 apolipoprotein L domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C2ORF54 chromosome 2 open reading frame 54
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CEP170B centrosomal protein 170B
CLSPN claspin
CORO2A coronin, actin binding protein, 2A
CUEDC1 CUE domain containing 1
DSCAM Down syndrome cell adhesion molecule
EDAR ectodysplasin A receptor
ERN2 endoplasmic reticulum to nucleus signaling 2
FA2H fatty acid 2-hydroxylase
FAM118A family with sequence similarity 118, member A
FAM120C family with sequence similarity 120C
FAM186A family with sequence similarity 186, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGD6 FYVE, RhoGEF and PH domain containing 6
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FLJ22184
FOSL1 FOS-like antigen 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPC3 glypican 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
IFI6 interferon, alpha-inducible protein 6
IPO13 importin 13
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCTD17 potassium channel tetramerization domain containing 17
KIF13A kinesin family member 13A
KLK5 kallikrein-related peptidase 5
LIN7B lin-7 homolog B (C. elegans)
LYPLA2P1 lysophospholipase II pseudogene 1
MAP1S microtubule-associated protein 1S
MAP7D1 MAP7 domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MITF microphthalmia-associated transcription factor
MUC3B mucin 3B, cell surface associated
NARFL nuclear prelamin A recognition factor-like
NRTN neurturin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P3H1 prolyl 3-hydroxylase 1
PAIP2B poly(A) binding protein interacting protein 2B
PANK4 pantothenate kinase 4
PGPEP1 pyroglutamyl-peptidase I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3A RAB3A, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A2 S100 calcium binding protein A2
SALL2 spalt-like transcription factor 2
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLIT2 slit homolog 2 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TH tyrosine hydroxylase
TMEM180 transmembrane protein 180
TPCN1 two pore segment channel 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN5 tetraspanin 5
TSSC4 tumor suppressing subtransferable candidate 4
TTBK2 tau tubulin kinase 2
TTC26 tetratricopeptide repeat domain 26
UBXN6 UBX domain protein 6
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
WDR19 WD repeat domain 19
WDR25 WD repeat domain 25
ZC3H12A zinc finger CCCH-type containing 12A
ZNF205 zinc finger protein 205
ZNF35 zinc finger protein 35
ZNF37BP zinc finger protein 37B, pseudogene
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696