minoxidil-4216 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the minoxidil-4216 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM22 ADAM metallopeptidase domain 22
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ALOX15B arachidonate 15-lipoxygenase, type B
ATXN2L ataxin 2-like
BIRC7 baculoviral IAP repeat containing 7
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP7 bone morphogenetic protein 7
C17ORF53 chromosome 17 open reading frame 53
CASQ2 calsequestrin 2 (cardiac muscle)
CCKAR cholecystokinin A receptor
CDHR5 cadherin-related family member 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CNOT3 CCR4-NOT transcription complex, subunit 3
COL10A1 collagen, type X, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CTRC chymotrypsin C (caldecrin)
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DAPK2 death-associated protein kinase 2
DCC DCC netrin 1 receptor
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
EDDM3B epididymal protein 3B
EPO erythropoietin
FAM212B family with sequence similarity 212, member B
FGB fibrinogen beta chain
FGF3 fibroblast growth factor 3
FRMD4B FERM domain containing 4B
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
HAMP hepcidin antimicrobial peptide
HBB hemoglobin, beta
HNF1B HNF1 homeobox B
HOXB3 homeobox B3
HOXD10 homeobox D10
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICA1 islet cell autoantigen 1, 69kDa
IHH indian hedgehog
IL12B interleukin 12B
IL16 interleukin 16
JUND jun D proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0125 KIAA0125
KIF25 kinesin family member 25
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KL klotho
KLK3 kallikrein-related peptidase 3
KRT32 keratin 32, type I
KSR1 kinase suppressor of ras 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LYZ lysozyme
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MPPE1 metallophosphoesterase 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMUR1 neuromedin U receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
NRP2 neuropilin 2
PADI4 peptidyl arginine deiminase, type IV
PDLIM5 PDZ and LIM domain 5
PMP2 peripheral myelin protein 2
PRAMEF10 PRAME family member 10
PRLR prolactin receptor
PYY peptide YY
RAB36 RAB36, member RAS oncogene family
RAD51B RAD51 paralog B
RDH8 retinol dehydrogenase 8 (all-trans)
REG1A regenerating islet-derived 1 alpha
RGS1 regulator of G-protein signaling 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
SCAND2P SCAN domain containing 2 pseudogene
SH3PXD2A SH3 and PX domains 2A
SLAMF7 SLAM family member 7
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TLN2 talin 2
TNNT3 troponin T type 3 (skeletal, fast)
TNS1 tensin 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TSHR thyroid stimulating hormone receptor
TSSK2 testis-specific serine kinase 2
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
ZNF280A zinc finger protein 280A
ZNF407 zinc finger protein 407
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AEN apoptosis enhancing nuclease
ANKFY1 ankyrin repeat and FYVE domain containing 1
AXIN1 axin 1
BAG4 BCL2-associated athanogene 4
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BOLA1 bolA family member 1
C16ORF59 chromosome 16 open reading frame 59
C3ORF18 chromosome 3 open reading frame 18
CASZ1 castor zinc finger 1
CBX7 chromobox homolog 7
CCDC88C coiled-coil domain containing 88C
CLCN5 chloride channel, voltage-sensitive 5
CLDN11 claudin 11
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CTSF cathepsin F
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLK2 delta-like 2 homolog (Drosophila)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM186A family with sequence similarity 186, member A
FER fer (fps/fes related) tyrosine kinase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GLDC glycine dehydrogenase (decarboxylating)
GLT8D2 glycosyltransferase 8 domain containing 2
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HMHA1 histocompatibility (minor) HA-1
HOXA1 homeobox A1
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KPTN kaptin (actin binding protein)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIG4 ligase IV, DNA, ATP-dependent
LPPR4 lipid phosphate phosphatase-related protein type 4
MANBA mannosidase, beta A, lysosomal
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM3AP-AS1 MCM3AP antisense RNA 1
MED23 mediator complex subunit 23
METTL16 methyltransferase like 16
MGC12488
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYNN myoneurin
NCS1 neuronal calcium sensor 1
NDRG4 NDRG family member 4
NUP62CL nucleoporin 62kDa C-terminal like
OTUD3 OTU deubiquitinase 3
PADI1 peptidyl arginine deiminase, type I
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCOLCE procollagen C-endopeptidase enhancer
PECR peroxisomal trans-2-enoyl-CoA reductase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
POM121 POM121 transmembrane nucleoporin
PRR14L proline rich 14-like
RGS17 regulator of G-protein signaling 17
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERINC5 serine incorporator 5
SETD6 SET domain containing 6
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
TAGLN3 transgelin 3
TGDS TDP-glucose 4,6-dehydratase
THRAP3 thyroid hormone receptor associated protein 3
TMEM186 transmembrane protein 186
TMEM242 transmembrane protein 242
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
UBXN8 UBX domain protein 8
ZBTB44 zinc finger and BTB domain containing 44
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF10 zinc finger protein 10
ZNF286A zinc finger protein 286A
ZNF33B zinc finger protein 33B
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF668 zinc finger protein 668