migraine Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (Human Disease Ontology, DOID_6364)
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Genes

47 genes associated with the disease migraine in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AR androgen receptor
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DIDO1 death inducer-obliterator 1
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EFHC1 EF-hand domain (C-terminal) containing 1
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL1A interleukin 1, alpha
INSR insulin receptor
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MEP1A meprin A, alpha (PABA peptide hydrolase)
MTDH metadherin
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NNMT nicotinamide N-methyltransferase
PGR progesterone receptor
RHAG Rh-associated glycoprotein
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC25A27 solute carrier family 25, member 27
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TNF tumor necrosis factor
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPH1 tryptophan hydroxylase 1
TYMS thymidylate synthetase