migraine without aura Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A migraine that is characterized by migraine headaches that are not accompanied by an aura. (Human Disease Ontology, DOID_12783)
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Genes

126 genes co-occuring with the disease migraine without aura in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.70406
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.53921
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.53304
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.4149
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.31624
PRDM16 PR domain containing 16 1.18755
KCNK18 potassium channel, two pore domain subfamily K, member 18 1.10931
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 1.08957
CALCA calcitonin-related polypeptide alpha 1.0753
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.0669
DRD4 dopamine receptor D4 1.00752
ITPK1 inositol-tetrakisphosphate 1-kinase 1.00541
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.955779
DRD2 dopamine receptor D2 0.950769
HCRTR2 hypocretin (orexin) receptor 2 0.937459
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.888029
DRD3 dopamine receptor D3 0.880243
PRRT2 proline-rich transmembrane protein 2 0.878605
ASTN2 astrotactin 2 0.876966
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.859362
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.856905
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.849945
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.843802
MAOA monoamine oxidase A 0.838476
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.828229
TSPAN2 tetraspanin 2 0.822897
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.821667
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.80936
DRD5 dopamine receptor D5 0.799513
TBX15 T-box 15 0.774114
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.761047
NOTCH3 notch 3 0.74883
PHACTR1 phosphatase and actin regulator 1 0.729357
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.728143
DRD1 dopamine receptor D1 0.727738
MAVS mitochondrial antiviral signaling protein 0.72127
NOTCH4 notch 4 0.717635
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.712392
TAAR1 trace amine associated receptor 1 0.698313
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.686691
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.6608
HCRTR1 hypocretin (orexin) receptor 1 0.645375
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.636315
HCRT hypocretin (orexin) neuropeptide precursor 0.630027
PRAMEF6 PRAME family member 6 0.625711
STX1A syntaxin 1A (brain) 0.625711
PRL prolactin 0.590558
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.578494
NPS neuropeptide S 0.573439
POMC proopiomelanocortin 0.572273
MEF2D myocyte enhancer factor 2D 0.551298
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.547419
PNKD paroxysmal nonkinesigenic dyskinesia 0.540055
NRIP1 nuclear receptor interacting protein 1 0.540055
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.528835
LTA lymphotoxin alpha 0.515725
HAS1 hyaluronan synthase 1 0.488169
TNF tumor necrosis factor 0.480186
PDE5A phosphodiesterase 5A, cGMP-specific 0.47753
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.463905
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.455978
PNMA1 paraneoplastic Ma antigen 1 0.446935
MAOB monoamine oxidase B 0.442418
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.438658
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.431144
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.424765
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.424389
CD72 CD72 molecule 0.418768
ACE angiotensin I converting enzyme 0.418394
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.415398
MRS2 MRS2 magnesium transporter 0.411283
HVCN1 hydrogen voltage gated channel 1 0.404184
SCN1A sodium channel, voltage gated, type I alpha subunit 0.403811
MGAM maltase-glucoamylase 0.390397
CLNK cytokine-dependent hematopoietic cell linker 0.383337
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.36187
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.361502
PF4 platelet factor 4 0.35892
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.35082
TPT1 tumor protein, translationally-controlled 1 0.343473
LRP5 low density lipoprotein receptor-related protein 5 0.339073
FXYD1 FXYD domain containing ion transport regulator 1 0.331391
TREX1 three prime repair exonuclease 1 0.32009
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.317909
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.316456
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.315366
IL1B interleukin 1, beta 0.308118
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.305587
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.303059
NOVA2 neuro-oncological ventral antigen 2 0.285802
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.285444
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.269043
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.268332
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.266558
NOS3 nitric oxide synthase 3 (endothelial cell) 0.251718
FEN1 flap structure-specific endonuclease 1 0.24996
IFT122 intraflagellar transport 122 0.247501
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.246799
PNOC prepronociceptin 0.245747
DNAH8 dynein, axonemal, heavy chain 8 0.241895
MGP matrix Gla protein 0.235616
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.235616
IL1A interleukin 1, alpha 0.231448
VAT1 vesicle amine transport 1 0.226262
NOS2 nitric oxide synthase 2, inducible 0.224884
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.224884
CD70 CD70 molecule 0.212608
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.207245
TAC1 tachykinin, precursor 1 0.202946
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.202946
VWF von Willebrand factor 0.200006
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.197099
SP6 Sp6 transcription factor 0.191408
CST7 cystatin F (leukocystatin) 0.188938
EDNRA endothelin receptor type A 0.186811
F5 coagulation factor V (proaccelerin, labile factor) 0.186811
COMT catechol-O-methyltransferase 0.17896
MFGE8 milk fat globule-EGF factor 8 protein 0.176215
PENK proenkephalin 0.175947
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.172291
LEP leptin 0.172038
MMP9 matrix metallopeptidase 9 0.172038
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.171036
SKP1 S-phase kinase-associated protein 1 0.160021
NPY neuropeptide Y 0.159302
TIMP2 TIMP metallopeptidase inhibitor 2 0.157929