midodrine-7156 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the midodrine-7156 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP28 Rho GTPase activating protein 28
ATF5 activating transcription factor 5
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AVL9 AVL9 homolog (S. cerevisiase)
BAIAP2 BAI1-associated protein 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BSPRY B-box and SPRY domain containing
BTN3A2 butyrophilin, subfamily 3, member A2
C16ORF58 chromosome 16 open reading frame 58
C7ORF43 chromosome 7 open reading frame 43
CCPG1 cell cycle progression 1
CFLAR CASP8 and FADD-like apoptosis regulator
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL5A1 collagen, type V, alpha 1
CTNND2 catenin (cadherin-associated protein), delta 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DFNB31 deafness, autosomal recessive 31
DOHH deoxyhypusine hydroxylase/monooxygenase
DRP2 dystrophin related protein 2
ELF4 E74-like factor 4 (ets domain transcription factor)
EPS8L1 EPS8-like 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERI3 ERI1 exoribonuclease family member 3
FAM13A family with sequence similarity 13, member A
FGF1 fibroblast growth factor 1 (acidic)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATA2 GATA binding protein 2
GK glycerol kinase
GLI2 GLI family zinc finger 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
H2AFX H2A histone family, member X
HDAC9 histone deacetylase 9
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HK2 hexokinase 2
HOXA6 homeobox A6
IL1RAP interleukin 1 receptor accessory protein
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK3 interleukin-1 receptor-associated kinase 3
JAK2 Janus kinase 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT34 keratin 34, type I
LIMK1 LIM domain kinase 1
LMBR1L limb development membrane protein 1-like
LRP1 low density lipoprotein receptor-related protein 1
LRP3 low density lipoprotein receptor-related protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MECP2 methyl CpG binding protein 2
MLH3 mutL homolog 3
MPI mannose phosphate isomerase
MXRA8 matrix-remodelling associated 8
MYL10 myosin, light chain 10, regulatory
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NLRX1 NLR family member X1
NUDCD3 NudC domain containing 3
OPRL1 opiate receptor-like 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDLIM5 PDZ and LIM domain 5
PELI2 pellino E3 ubiquitin protein ligase family member 2
PLCD1 phospholipase C, delta 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB33B RAB33B, member RAS oncogene family
RAD54B RAD54 homolog B (S. cerevisiae)
RANBP3 RAN binding protein 3
SEC24D SEC24 family member D
SEC63 SEC63 homolog (S. cerevisiae)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRD5A3 steroid 5 alpha-reductase 3
SSH3 slingshot protein phosphatase 3
TCF3 transcription factor 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM212 transmembrane protein 212
TMF1 TATA element modulatory factor 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC38 tetratricopeptide repeat domain 38
TTLL5 tubulin tyrosine ligase-like family member 5
USP20 ubiquitin specific peptidase 20
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZFHX3 zinc finger homeobox 3
ZNF197 zinc finger protein 197
ZNF79 zinc finger protein 79
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTN4 actinin, alpha 4
ADCY7 adenylate cyclase 7
ADGRF1 adhesion G protein-coupled receptor F1
AEN apoptosis enhancing nuclease
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATAD5 ATPase family, AAA domain containing 5
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
C2ORF42 chromosome 2 open reading frame 42
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC68 coiled-coil domain containing 68
CCDC69 coiled-coil domain containing 69
CCNJL cyclin J-like
CLCF1 cardiotrophin-like cytokine factor 1
CLEC16A C-type lectin domain family 16, member A
DCLRE1B DNA cross-link repair 1B
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKD diacylglycerol kinase, delta 130kDa
DLK2 delta-like 2 homolog (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EAF2 ELL associated factor 2
ECI1 enoyl-CoA delta isomerase 1
EDC3 enhancer of mRNA decapping 3
EFNA4 ephrin-A4
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
ERCC2 excision repair cross-complementation group 2
ERF Ets2 repressor factor
FAM155A family with sequence similarity 155, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GAB2 GRB2-associated binding protein 2
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR4 G protein-coupled receptor 4
HIST1H1D histone cluster 1, H1d
KATNBL1 katanin p80 subunit B-like 1
KIAA0895 KIAA0895
LOC730101 uncharacterized LOC730101
MMP1 matrix metallopeptidase 1
MOCS3 molybdenum cofactor synthesis 3
MRPL44 mitochondrial ribosomal protein L44
MTG1 mitochondrial ribosome-associated GTPase 1
MUM1 melanoma associated antigen (mutated) 1
NCS1 neuronal calcium sensor 1
NPM3 nucleophosmin/nucleoplasmin 3
OXR1 oxidation resistance 1
OXTR oxytocin receptor
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHJ1 pleckstrin homology domain containing, family J member 1
POLM polymerase (DNA directed), mu
PPCS phosphopantothenoylcysteine synthetase
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRMT7 protein arginine methyltransferase 7
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSPC1 paraspeckle component 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB3A RAB3A, member RAS oncogene family
RBL1 retinoblastoma-like 1
RGS19 regulator of G-protein signaling 19
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
SCAI suppressor of cancer cell invasion
SCAMP5 secretory carrier membrane protein 5
SDAD1 SDA1 domain containing 1
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SIPA1 signal-induced proliferation-associated 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX10 sorting nexin 10
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THAP10 THAP domain containing 10
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMEM38B transmembrane protein 38B
TNS2 tensin 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UBTD1 ubiquitin domain containing 1
UBXN2B UBX domain protein 2B
USP39 ubiquitin specific peptidase 39
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
YOD1 YOD1 deubiquitinase
ZBTB24 zinc finger and BTB domain containing 24
ZNF33B zinc finger protein 33B
ZNF385D zinc finger protein 385D
ZNF408 zinc finger protein 408