midbrain Gene Set

Dataset Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles
Category transcriptomics
Type tissue
Description The middle of the three primary divisions of the developing vertebrate brain or the corresponding part of the adult brain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000138)
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Genes

173 genes with high or low expression in midbrain relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
IFNA4 interferon, alpha 4 1.34053
SAMD11 sterile alpha motif domain containing 11 1.30728
OPLAH 5-oxoprolinase (ATP-hydrolysing) 1.30416
UBQLN2 ubiquilin 2 1.29847
ACTBL2 actin, beta-like 2 1.28015
MPL MPL proto-oncogene, thrombopoietin receptor 1.24799
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.15325
EXD1 exonuclease 3'-5' domain containing 1 1.15049
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 1.13283
SOX14 SRY (sex determining region Y)-box 14 1.10984
WDR73 WD repeat domain 73 1.09599
ELP4 elongator acetyltransferase complex subunit 4 1.09204
FAM3B family with sequence similarity 3, member B 1.0896
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.08391
ANGPT4 angiopoietin 4 1.07586
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.07028
C19ORF40 chromosome 19 open reading frame 40 1.05594
APOH apolipoprotein H (beta-2-glycoprotein I) 1.0544
CYSLTR2 cysteinyl leukotriene receptor 2 1.05175
MRGPRX4 MAS-related GPR, member X4 1.02873
ZNF467 zinc finger protein 467 1.02147
POFUT1 protein O-fucosyltransferase 1 1.02047
BNC2 basonuclin 2 1.00074

low expression

Symbol Name Standardized Value
PRR15L proline rich 15-like -2.26607
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -2.26111
SRPX sushi-repeat containing protein, X-linked -2.19282
GOLGA4 golgin A4 -2.17726
SYCE1 synaptonemal complex central element protein 1 -2.06725
EGF epidermal growth factor -2.00445
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -1.99836
TFPI2 tissue factor pathway inhibitor 2 -1.98366
MNX1 motor neuron and pancreas homeobox 1 -1.97167
PGLYRP3 peptidoglycan recognition protein 3 -1.89256
LAPTM5 lysosomal protein transmembrane 5 -1.8623
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -1.84145
RCCD1 RCC1 domain containing 1 -1.74084
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D -1.73005
OR2T8 olfactory receptor, family 2, subfamily T, member 8 -1.72765
TFF3 trefoil factor 3 (intestinal) -1.68783
ADCK4 aarF domain containing kinase 4 -1.65449
CYTIP cytohesin 1 interacting protein -1.6444
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -1.6349
PLIN1 perilipin 1 -1.59919
CCND2 cyclin D2 -1.58423
RNF224 ring finger protein 224 -1.57266
KISS1 KiSS-1 metastasis-suppressor -1.5671
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 -1.5595
WDR41 WD repeat domain 41 -1.55249
PRC1 protein regulator of cytokinesis 1 -1.54148
IL1A interleukin 1, alpha -1.54022
LAD1 ladinin 1 -1.53304
ACVR1C activin A receptor, type IC -1.53026
EXOSC6 exosome component 6 -1.49967
NR5A1 nuclear receptor subfamily 5, group A, member 1 -1.49947
TP53INP1 tumor protein p53 inducible nuclear protein 1 -1.48411
AURKB aurora kinase B -1.46486
SLC22A14 solute carrier family 22, member 14 -1.46292
TSHR thyroid stimulating hormone receptor -1.46045
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -1.45894
MIA2 melanoma inhibitory activity 2 -1.44026
SPACA1 sperm acrosome associated 1 -1.4238
TAS1R2 taste receptor, type 1, member 2 -1.42219
NUF2 NUF2, NDC80 kinetochore complex component -1.40289
TECTA tectorin alpha -1.37226
ZHX3 zinc fingers and homeoboxes 3 -1.37221
CDCA7 cell division cycle associated 7 -1.37092
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -1.3618
ZBTB14 zinc finger and BTB domain containing 14 -1.35423
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -1.34708
SNX8 sorting nexin 8 -1.34524
GLB1L2 galactosidase, beta 1-like 2 -1.3362
RPL7L1 ribosomal protein L7-like 1 -1.33475
ELF2 E74-like factor 2 (ets domain transcription factor) -1.32876
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 -1.32015
EFNA4 ephrin-A4 -1.30977
DNAH10 dynein, axonemal, heavy chain 10 -1.30695
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -1.30388
LRRIQ4 leucine-rich repeats and IQ motif containing 4 -1.28884
IL17F interleukin 17F -1.28277
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -1.27255
PIBF1 progesterone immunomodulatory binding factor 1 -1.27204
DSC2 desmocollin 2 -1.26938
FFAR2 free fatty acid receptor 2 -1.26551
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.25346
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -1.2453
C6ORF165 chromosome 6 open reading frame 165 -1.24397
AQP1 aquaporin 1 (Colton blood group) -1.24269
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 -1.23663
SLC22A24 solute carrier family 22, member 24 -1.23311
HARS histidyl-tRNA synthetase -1.22758
ACTN4 actinin, alpha 4 -1.22522
BPIFA2 BPI fold containing family A, member 2 -1.22112
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -1.21615
NFE2L2 nuclear factor, erythroid 2-like 2 -1.20361
PPP1R3A protein phosphatase 1, regulatory subunit 3A -1.20328
DMRTA1 DMRT-like family A1 -1.19801
DCAF10 DDB1 and CUL4 associated factor 10 -1.19735
ADGRF1 adhesion G protein-coupled receptor F1 -1.19254
KLHL25 kelch-like family member 25 -1.19136
FAM198A family with sequence similarity 198, member A -1.191
LIPT1 lipoyltransferase 1 -1.19042
BMP1 bone morphogenetic protein 1 -1.17385
ELOVL7 ELOVL fatty acid elongase 7 -1.16651
ZNF394 zinc finger protein 394 -1.15732
MEP1A meprin A, alpha (PABA peptide hydrolase) -1.14082
KLHL15 kelch-like family member 15 -1.13992
GLS glutaminase -1.13485
DNASE1 deoxyribonuclease I -1.13338
NADSYN1 NAD synthetase 1 -1.13106
MYRF myelin regulatory factor -1.13089
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -1.12916
CLDN8 claudin 8 -1.11483
SMG5 SMG5 nonsense mediated mRNA decay factor -1.11425
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -1.11126
CLDN14 claudin 14 -1.10296
GCC2 GRIP and coiled-coil domain containing 2 -1.10288
APH1A APH1A gamma secretase subunit -1.10266
WEE2 WEE1 homolog 2 (S. pombe) -1.09771
APOL6 apolipoprotein L, 6 -1.09432
FMO2 flavin containing monooxygenase 2 (non-functional) -1.09391
GSDMA gasdermin A -1.09255
OXT oxytocin/neurophysin I prepropeptide -1.09088
ZNF488 zinc finger protein 488 -1.09019
GRM2 glutamate receptor, metabotropic 2 -1.09007
PEX11G peroxisomal biogenesis factor 11 gamma -1.08771
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -1.08621
BACE2 beta-site APP-cleaving enzyme 2 -1.08556
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.08452
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -1.08423
OOEP oocyte expressed protein -1.08331
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.07398
YAP1 Yes-associated protein 1 -1.07324
ZC3H8 zinc finger CCCH-type containing 8 -1.07062
ZXDC ZXD family zinc finger C -1.0673
ZNF672 zinc finger protein 672 -1.05997
STRC stereocilin -1.05892
FRZB frizzled-related protein -1.05892
BAIAP2L2 BAI1-associated protein 2-like 2 -1.05818
CLOCK clock circadian regulator -1.05597
PCDHB14 protocadherin beta 14 -1.05498
PARP9 poly (ADP-ribose) polymerase family, member 9 -1.05445
NUP43 nucleoporin 43kDa -1.05013
PHF6 PHD finger protein 6 -1.04773
ZBTB48 zinc finger and BTB domain containing 48 -1.04689
C5ORF30 chromosome 5 open reading frame 30 -1.0457
LY96 lymphocyte antigen 96 -1.03821
SMC1B structural maintenance of chromosomes 1B -1.03648
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -1.03552
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -1.03164
TMEM39B transmembrane protein 39B -1.02976
SMIM20 small integral membrane protein 20 -1.02866
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -1.02822
HOXB8 homeobox B8 -1.02798
LARP1 La ribonucleoprotein domain family, member 1 -1.02678
ARF3 ADP-ribosylation factor 3 -1.026
ZAN zonadhesin (gene/pseudogene) -1.0232
DYTN dystrotelin -1.02269
MYO5B myosin VB -1.0223
JMJD8 jumonji domain containing 8 -1.02141
SLC39A2 solute carrier family 39 (zinc transporter), member 2 -1.02119
MCTP1 multiple C2 domains, transmembrane 1 -1.02101
PLBD1 phospholipase B domain containing 1 -1.01782
DCAF5 DDB1 and CUL4 associated factor 5 -1.01722
CASS4 Cas scaffolding protein family member 4 -1.01625
FOXA3 forkhead box A3 -1.01618
ACADSB acyl-CoA dehydrogenase, short/branched chain -1.01429
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) -1.0135
ZNF595 zinc finger protein 595 -1.01338
SLC10A7 solute carrier family 10, member 7 -1.00824
TTC30A tetratricopeptide repeat domain 30A -1.00657
FBXO6 F-box protein 6 -1.0028
TSSK3 testis-specific serine kinase 3 -1.00146
NKAIN2 Na+/K+ transporting ATPase interacting 2 -1.00094