midbrain central gray Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Central gray matter surrounding the cerebral aqueduct in the mesencephalon. Physiologically it is probably involved in rage reactions, the lordosis reflex, feeding responses, bladder tonus, and pain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002701)
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Genes

171 proteins co-occuring with the tissue midbrain central gray in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FOS FBJ murine osteosarcoma viral oncogene homolog 2.43245
OPRM1 opioid receptor, mu 1 2.27722
PNOC prepronociceptin 1.86358
NTS neurotensin 1.76325
TAC1 tachykinin, precursor 1 1.68404
POMC proopiomelanocortin 1.66407
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.50858
TH tyrosine hydroxylase 1.46775
CNR1 cannabinoid receptor 1 (brain) 1.42045
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.41169
OPRK1 opioid receptor, kappa 1 1.36587
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.36177
CCK cholecystokinin 1.36131
NPS neuropeptide S 1.34995
CRH corticotropin releasing hormone 1.29489
PENK proenkephalin 1.28278
OPRL1 opiate receptor-like 1 1.2586
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.25458
PDYN prodynorphin 1.23584
PSENEN presenilin enhancer gamma secretase subunit 1.23182
RLN3 relaxin 3 1.2296
PTH2 parathyroid hormone 2 1.22425
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.15983
HCRT hypocretin (orexin) neuropeptide precursor 1.13723
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.11951
FAAH fatty acid amide hydrolase 1.1027
TACR1 tachykinin receptor 1 1.10181
TPH1 tryptophan hydroxylase 1 1.08899
NTSR2 neurotensin receptor 2 1.0806
MEA1 male-enhanced antigen 1 1.07265
NCF4 neutrophil cytosolic factor 4, 40kDa 1.07088
OPRD1 opioid receptor, delta 1 1.07044
TFIP11 tuftelin interacting protein 11 1.03127
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.96636
CHAT choline O-acetyltransferase 0.948239
SELM selenoprotein M 0.937488
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.936629
TRH thyrotropin-releasing hormone 0.934054
BAIAP3 BAI1-associated protein 3 0.924623
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.919916
ARRB2 arrestin, beta 2 0.919488
PTH2R parathyroid hormone 2 receptor 0.916069
RGS11 regulator of G-protein signaling 11 0.90924
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.885015
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.870217
GAL galanin/GMAP prepropeptide 0.85547
CALCA calcitonin-related polypeptide alpha 0.843706
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.835318
SST somatostatin 0.834899
RGS7 regulator of G-protein signaling 7 0.826942
ESR1 estrogen receptor 1 0.813979
RGS14 regulator of G-protein signaling 14 0.808551
CRHR1 corticotropin releasing hormone receptor 1 0.807716
RXFP3 relaxin/insulin-like family peptide receptor 3 0.803544
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.80271
STK38 serine/threonine kinase 38 0.77774
PTK7 protein tyrosine kinase 7 (inactive) 0.767783
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.766954
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.74834
MYRF myelin regulatory factor 0.742976
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.735147
JAG2 jagged 2 0.734323
NPY neuropeptide Y 0.729797
MC4R melanocortin 4 receptor 0.724041
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.711319
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.7105
GRM5 glutamate receptor, metabotropic 5 0.706402
LHB luteinizing hormone beta polypeptide 0.704764
PGM3 phosphoglucomutase 3 0.696581
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 0.690042
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.683511
AVP arginine vasopressin 0.68188
TECTA tectorin alpha 0.675357
OR13H1 olfactory receptor, family 13, subfamily H, member 1 0.659491
NPB neuropeptide B 0.640833
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 0.637999
KNG1 kininogen 1 0.631527
NPFF neuropeptide FF-amide peptide precursor 0.627889
ARRB1 arrestin, beta 1 0.6182
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.608124
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 0.604904
EGR1 early growth response 1 0.604099
NTSR1 neurotensin receptor 1 (high affinity) 0.594451
GRM7 glutamate receptor, metabotropic 7 0.588832
CRHR2 corticotropin releasing hormone receptor 2 0.586026
PORCN porcupine homolog (Drosophila) 0.583621
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.581218
NPBWR2 neuropeptides B/W receptor 2 0.579617
GRP gastrin-releasing peptide 0.577215
NPW neuropeptide W 0.564035
MME membrane metallo-endopeptidase 0.557263
GRM1 glutamate receptor, metabotropic 1 0.544549
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.536229
CGA glycoprotein hormones, alpha polypeptide 0.521223
NPSR1 neuropeptide S receptor 1 0.511778
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.500398
RGS17 regulator of G-protein signaling 17 0.497657
RGS20 regulator of G-protein signaling 20 0.484376
TRIM37 tripartite motif containing 37 0.482428
RGS9 regulator of G-protein signaling 9 0.468824
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.45374
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.443347
SEMG1 semenogelin I 0.426109
CCKBR cholecystokinin B receptor 0.412011
GRIK4 glutamate receptor, ionotropic, kainate 4 0.41087
BDNF brain-derived neurotrophic factor 0.402144
TPH2 tryptophan hydroxylase 2 0.393819
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.391931
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.391553
EPRS glutamyl-prolyl-tRNA synthetase 0.390044
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.389666
PVALB parvalbumin 0.387404
DLD dihydrolipoamide dehydrogenase 0.378748
EDN1 endothelin 1 0.375368
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.373493
PNMT phenylethanolamine N-methyltransferase 0.360409
SP6 Sp6 transcription factor 0.35334
TOM1 target of myb1 (chicken) 0.348519
RGS6 regulator of G-protein signaling 6 0.342602
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.342233
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.341863
ADCY2 adenylate cyclase 2 (brain) 0.340388
SALL4 spalt-like transcription factor 4 0.338545
FAT1 FAT atypical cadherin 1 0.338177
TXNL4B thioredoxin-like 4B 0.336704
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.336704
RGS10 regulator of G-protein signaling 10 0.324239
ACHE acetylcholinesterase (Yt blood group) 0.32205
UCN urocortin 0.320956
PLCE1 phospholipase C, epsilon 1 0.316951
CRCP CGRP receptor component 0.316588
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.316224
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.314046
DLL1 delta-like 1 (Drosophila) 0.31187
GRM4 glutamate receptor, metabotropic 4 0.31187
TTK TTK protein kinase 0.305361
ACE angiotensin I converting enzyme 0.303919
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.298883
SULT4A1 sulfotransferase family 4A, member 1 0.298524
SON SON DNA binding protein 0.29673
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.296013
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.294581
ZBTB32 zinc finger and BTB domain containing 32 0.293866
GSTM1 glutathione S-transferase mu 1 0.292079
PLCG1 phospholipase C, gamma 1 0.281423
TACR3 tachykinin receptor 3 0.280364
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.280364
NDEL1 nudE neurodevelopment protein 1-like 1 0.277197
RD3 retinal degeneration 3 0.275094
NGF nerve growth factor (beta polypeptide) 0.272997
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.270909
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.268482
XPR1 xenotropic and polytropic retrovirus receptor 1 0.261624
UNC13B unc-13 homolog B (C. elegans) 0.259929
CALCR calcitonin receptor 0.259591
DCX doublecortin 0.256568
CA13 carbonic anhydrase XIII 0.256568
HDC histidine decarboxylase 0.255567
LSAMP limbic system-associated membrane protein 0.25457
GRIK1 glutamate receptor, ionotropic, kainate 1 0.249006
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.245175
AR androgen receptor 0.243605
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.241132
MAPT microtubule-associated protein tau 0.240826
NPBWR1 neuropeptides B/W receptor 1 0.234302
GALR3 galanin receptor 3 0.224645
ROM1 retinal outer segment membrane protein 1 0.224398
OPN4 opsin 4 0.223662
IARS isoleucyl-tRNA synthetase 0.220831
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.219707
GLB1 galactosidase, beta 1 0.217762