mhc protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. (Gene Ontology, GO_0042611)
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Genes

371 proteins co-occuring with the mhc protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD86 CD86 molecule 3.01763
CD4 CD4 molecule 2.81148
CD80 CD80 molecule 2.70815
HLA-B major histocompatibility complex, class I, B 2.6568
CD40 CD40 molecule, TNF receptor superfamily member 5 2.46654
CIITA class II, major histocompatibility complex, transactivator 2.46654
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.84497
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.75595
CD83 CD83 molecule 1.68543
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 1.63658
ICAM1 intercellular adhesion molecule 1 1.6342
HLA-DMA major histocompatibility complex, class II, DM alpha 1.59894
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.58737
HLA-A major histocompatibility complex, class I, A 1.57588
RFXAP regulatory factor X-associated protein 1.51638
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.44064
CD276 CD276 molecule 1.4288
B2M beta-2-microglobulin 1.3752
FOXP3 forkhead box P3 1.37464
CCR7 chemokine (C-C motif) receptor 7 1.35704
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 1.32275
LY75 lymphocyte antigen 75 1.32005
HLA-E major histocompatibility complex, class I, E 1.32005
CD1D CD1d molecule 1.30873
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.2809
TLR4 toll-like receptor 4 1.25443
RFX1 regulatory factor X, 1 (influences HLA class II expression) 1.24655
RFXANK regulatory factor X-associated ankyrin-containing protein 1.23975
TLR2 toll-like receptor 2 1.21686
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 1.19365
HLA-C major histocompatibility complex, class I, C 1.18389
CD69 CD69 molecule 1.13727
TAPBP TAP binding protein (tapasin) 1.13012
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.13012
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.12194
AIF1 allograft inflammatory factor 1 1.10766
TNF tumor necrosis factor 1.10358
CD1C CD1c molecule 1.09798
CD207 CD207 molecule, langerin 1.08425
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.07562
MICA MHC class I polypeptide-related sequence A 1.07258
EDA ectodysplasin A 1.05539
CD40LG CD40 ligand 1.03879
CD19 CD19 molecule 1.02082
IL1B interleukin 1, beta 1.00547
ZBTB7B zinc finger and BTB domain containing 7B 0.995632
CD68 CD68 molecule 0.995632
DHDH dihydrodiol dehydrogenase (dimeric) 0.994162
STAT1 signal transducer and activator of transcription 1, 91kDa 0.988294
SIRPA signal-regulatory protein alpha 0.983906
TLR9 toll-like receptor 9 0.979044
CD44 CD44 molecule (Indian blood group) 0.976135
MYD88 myeloid differentiation primary response 88 0.974198
CD5 CD5 molecule 0.963107
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.937377
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.933601
HLA-G major histocompatibility complex, class I, G 0.925135
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.909716
LAG3 lymphocyte-activation gene 3 0.901353
NCR1 natural cytotoxicity triggering receptor 1 0.897183
ZXDC ZXD family zinc finger C 0.885628
CD1B CD1b molecule 0.878251
IL4 interleukin 4 0.870885
CD163 CD163 molecule 0.868586
IFNA1 interferon, alpha 1 0.863528
IL2 interleukin 2 0.860311
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.855717
CCR2 chemokine (C-C motif) receptor 2 0.84791
IL10 interleukin 10 0.84791
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.844696
CD8A CD8a molecule 0.835056
MOG myelin oligodendrocyte glycoprotein 0.83322
MRC1 mannose receptor, C type 1 0.803855
PRF1 perforin 1 (pore forming protein) 0.797436
CD200 CD200 molecule 0.790564
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.790564
FOXN1 forkhead box N1 0.790106
ERAP1 endoplasmic reticulum aminopeptidase 1 0.785529
THY1 Thy-1 cell surface antigen 0.784614
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.778212
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.774558
PACS1 phosphofurin acidic cluster sorting protein 1 0.773188
ZXDA zinc finger, X-linked, duplicated A 0.769539
CD209 CD209 molecule 0.762252
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.754076
FLT3 fms-related tyrosine kinase 3 0.753623
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.749999
IRF1 interferon regulatory factor 1 0.746381
LAMP1 lysosomal-associated membrane protein 1 0.742769
MBP myelin basic protein 0.736464
IDO1 indoleamine 2,3-dioxygenase 1 0.721242
CD58 CD58 molecule 0.719015
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 0.715014
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.703507
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.699983
HCG4P11 HLA complex group 4 pseudogene 11 0.699103
HLA-F major histocompatibility complex, class I, F 0.699103
ITGAD integrin, alpha D 0.678543
CXCL10 chemokine (C-X-C motif) ligand 10 0.677238
CCL2 chemokine (C-C motif) ligand 2 0.668559
HFE hemochromatosis 0.66164
VCAM1 vascular cell adhesion molecule 1 0.653019
TSPO translocator protein (18kDa) 0.651299
TGFB1 transforming growth factor, beta 1 0.647433
PMEL premelanosome protein 0.641001
TRAC T cell receptor alpha constant 0.638005
IFNG interferon, gamma 0.624781
FER fer (fps/fes related) tyrosine kinase 0.616709
CS citrate synthase 0.606128
SPPL2A signal peptide peptidase like 2A 0.604017
CD79A CD79a molecule, immunoglobulin-associated alpha 0.598117
LYZ lysozyme 0.596435
CD34 CD34 molecule 0.594753
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.581758
ARG1 arginase 1 0.579251
TFRC transferrin receptor 0.575495
CD48 CD48 molecule 0.571745
TLR3 toll-like receptor 3 0.567169
DCT dopachrome tautomerase 0.566338
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.558042
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.553491
GJB6 gap junction protein, beta 6, 30kDa 0.547297
PTPRC protein tyrosine phosphatase, receptor type, C 0.542352
FASLG Fas ligand (TNF superfamily, member 6) 0.537416
SOCS1 suppressor of cytokine signaling 1 0.534951
MICB MHC class I polypeptide-related sequence B 0.531258
TYROBP TYRO protein tyrosine kinase binding protein 0.530438
CTSS cathepsin S 0.524704
IL6 interleukin 6 0.523885
CALR calreticulin 0.523067
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.520206
AIRE autoimmune regulator 0.518165
CCL21 chemokine (C-C motif) ligand 21 0.514085
CCL19 chemokine (C-C motif) ligand 19 0.512455
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.510826
LCK LCK proto-oncogene, Src family tyrosine kinase 0.50879
CCL3 chemokine (C-C motif) ligand 3 0.50635
CXCL9 chemokine (C-X-C motif) ligand 9 0.501881
MYBPC1 myosin binding protein C, slow type 0.499853
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.492966
RAE1 ribonucleic acid export 1 0.492157
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.4865
ARF6 ADP-ribosylation factor 6 0.484886
S100A9 S100 calcium binding protein A9 0.483676
BCR breakpoint cluster region 0.480855
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.48005
CD81 CD81 molecule 0.478038
NCAM1 neural cell adhesion molecule 1 0.472813
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.471208
MRPL33 mitochondrial ribosomal protein L33 0.469604
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.468001
RAG1 recombination activating gene 1 0.465198
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.461998
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.457208
IL2RA interleukin 2 receptor, alpha 0.457208
RAG2 recombination activating gene 2 0.456012
CD9 CD9 molecule 0.455214
MEX3C mex-3 RNA binding family member C 0.452029
CD200R1 CD200 receptor 1 0.446465
IL1A interleukin 1, alpha 0.439728
PARK2 parkin RBR E3 ubiquitin protein ligase 0.43696
NOS2 nitric oxide synthase 2, inducible 0.432224
CD247 CD247 molecule 0.432224
HSPA4 heat shock 70kDa protein 4 0.429465
FGF6 fibroblast growth factor 6 0.429072
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.427891
IRF4 interferon regulatory factor 4 0.427104
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.424353
IGF1 insulin-like growth factor 1 (somatomedin C) 0.418077
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.415728
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.41143
GFAP glial fibrillary acidic protein 0.407919
IL12B interleukin 12B 0.40675
MARCH9 membrane-associated ring finger (C3HC4) 9 0.405582
ZBTB46 zinc finger and BTB domain containing 46 0.403248
PRDM1 PR domain containing 1, with ZNF domain 0.398199
NELFCD negative elongation factor complex member C/D 0.393162
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.387365
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.386593
CD8B CD8b molecule 0.386208
CCL22 chemokine (C-C motif) ligand 22 0.385051
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 0.382354
RETNLB resistin like beta 0.381584
MYF6 myogenic factor 6 (herculin) 0.380814
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.379276
LTA lymphotoxin alpha 0.379276
ZCCHC7 zinc finger, CCHC domain containing 7 0.377738
IL15 interleukin 15 0.374283
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 0.373132
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.370833
IL17A interleukin 17A 0.368153
BTNL2 butyrophilin-like 2 0.362804
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.361277
CD63 CD63 molecule 0.357467
CD274 CD274 molecule 0.355183
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.352522
CD37 CD37 molecule 0.347208
SELL selectin L 0.339639
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.339261
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.338128
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.333602
TLR7 toll-like receptor 7 0.332472
CD38 CD38 molecule 0.327581
CCL5 chemokine (C-C motif) ligand 5 0.326078
ULBP1 UL16 binding protein 1 0.3227
CANX calnexin 0.320077
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 0.317456
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.315212
IRAK3 interleukin-1 receptor-associated kinase 3 0.314465
IFNB1 interferon, beta 1, fibroblast 0.314091
CFAP70 cilia and flagella associated protein 70 0.309613
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.307749
DERL1 derlin 1 0.305888
IFNGR1 interferon gamma receptor 1 0.302912
FUT2 fucosyltransferase 2 (secretor status included) 0.302168
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.301425
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.300311
ICAM2 intercellular adhesion molecule 2 0.298455
DNAH8 dynein, axonemal, heavy chain 8 0.297342
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.296972
MSR1 macrophage scavenger receptor 1 0.296972
SLC46A2 solute carrier family 46, member 2 0.295489
ICAM3 intercellular adhesion molecule 3 0.293267
TSHR thyroid stimulating hormone receptor 0.292527
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.289938
SYK spleen tyrosine kinase 0.289569
TREM1 triggering receptor expressed on myeloid cells 1 0.28846
PLA2G4E phospholipase A2, group IVE 0.287721
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.286245
HCK HCK proto-oncogene, Src family tyrosine kinase 0.284032
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.281821
MLANA melan-A 0.278509
CD1A CD1a molecule 0.271167
SPATA19 spermatogenesis associated 19 0.270434
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.266042
IRF7 interferon regulatory factor 7 0.260931
VEGFA vascular endothelial growth factor A 0.260566
INS insulin 0.259837
LUM lumican 0.258745
SELE selectin E 0.257652
IRF2 interferon regulatory factor 2 0.254017
CD300C CD300c molecule 0.252927
HBA1 hemoglobin, alpha 1 0.248578
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.24713
JAK1 Janus kinase 1 0.246407
NLRC5 NLR family, CARD domain containing 5 0.246046
CD82 CD82 molecule 0.24424
IL23A interleukin 23, alpha subunit p19 0.243158
HBA2 hemoglobin, alpha 2 0.243158
LUZP6 leucine zipper protein 6 0.240276
CD59 CD59 molecule, complement regulatory protein 0.237042
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.234891
TSLP thymic stromal lymphopoietin 0.234533
TBX21 T-box 21 0.233817
EOMES eomesodermin 0.228464
RUNX3 runt-related transcription factor 3 0.225976
ERBB2 erb-b2 receptor tyrosine kinase 2 0.224913
CD53 CD53 molecule 0.224204
CD24 CD24 molecule 0.223497
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.22173
ARMC3 armadillo repeat containing 3 0.220321
UBASH3A ubiquitin associated and SH3 domain containing A 0.218212
CXCR3 chemokine (C-X-C motif) receptor 3 0.218212
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.217861
MRAP melanocortin 2 receptor accessory protein 0.215761
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.213322
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.212627
PDCD1LG2 programmed cell death 1 ligand 2 0.21124
CD27 CD27 molecule 0.210549
GMEB2 glucocorticoid modulatory element binding protein 2 0.209858
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.207451
CARD17 caspase recruitment domain family, member 17 0.205059
ARL14 ADP-ribosylation factor-like 14 0.202009
PACS2 phosphofurin acidic cluster sorting protein 2 0.202009
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.199993
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.199659
BSG basigin (Ok blood group) 0.199325
TG thyroglobulin 0.19733
CTCF CCCTC-binding factor (zinc finger protein) 0.196669
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.192423
TIGIT T cell immunoreceptor with Ig and ITIM domains 0.188274
UBE2J2 ubiquitin-conjugating enzyme E2, J2 0.185777
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.183935
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.183328
FURIN furin (paired basic amino acid cleaving enzyme) 0.183328
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.180634
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.179752
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.178299
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.177439
DLL1 delta-like 1 (Drosophila) 0.177154
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.174635
CKM creatine kinase, muscle 0.174087
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.172468
PDCD1 programmed cell death 1 0.172201
NFYB nuclear transcription factor Y, beta 0.171673
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.170629
NKG7 natural killer cell granule protein 7 0.16935
CYTH3 cytohesin 3 0.168349
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.167366
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.163865
CTSD cathepsin D 0.162763
JAK3 Janus kinase 3 0.160863
HLA-DOA major histocompatibility complex, class II, DO alpha 0.159268
MSTN myostatin 0.158882
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.157578
CCL25 chemokine (C-C motif) ligand 25 0.157397
CD1E CD1e molecule 0.157039
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.138373
IL17F interleukin 17F 0.137921
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.12865
DPPA5 developmental pluripotency associated 5 0.128634
PVRL3 poliovirus receptor-related 3 0.128474
OASL 2'-5'-oligoadenylate synthetase-like 0.128262
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.128163
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.127894
NLRP10 NLR family, pyrin domain containing 10 0.127792
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.127549
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.127497
CTAG2 cancer/testis antigen 2 0.126431
BAGE2 B melanoma antigen family, member 2 0.126334
BAG5 BCL2-associated athanogene 5 0.125717
GATA3 GATA binding protein 3 0.125574
MCOLN2 mucolipin 2 0.125491
MAGEA3 melanoma antigen family A3 0.125428
WARS tryptophanyl-tRNA synthetase 0.125407
PARP9 poly (ADP-ribose) polymerase family, member 9 0.125302
GAS7 growth arrest-specific 7 0.125175
HLX H2.0-like homeobox 0.125067
IL17RA interleukin 17 receptor A 0.124894
IL23R interleukin 23 receptor 0.124872
CLEC2D C-type lectin domain family 2, member D 0.12485
IL19 interleukin 19 0.12485
HLA-DMB major histocompatibility complex, class II, DM beta 0.124652
MX1 MX dynamin-like GTPase 1 0.124629
MT1E metallothionein 1E 0.124562
CSF1R colony stimulating factor 1 receptor 0.124539
COX5B cytochrome c oxidase subunit Vb 0.124472
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.124449
MAGEC1 melanoma antigen family C1 0.12429
CCR6 chemokine (C-C motif) receptor 6 0.124198
CLEC9A C-type lectin domain family 9, member A 0.124175
MCM8 minichromosome maintenance complex component 8 0.124152
HADH hydroxyacyl-CoA dehydrogenase 0.123894
BTNL9 butyrophilin-like 9 0.123798
NLRP4 NLR family, pyrin domain containing 4 0.123798
CD22 CD22 molecule 0.123751
GYPC glycophorin C (Gerbich blood group) 0.123703
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.123679
SKIL SKI-like proto-oncogene 0.123582
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.123558
PDPN podoplanin 0.123533
CD79B CD79b molecule, immunoglobulin-associated beta 0.123163
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.122961
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.122935
TLR6 toll-like receptor 6 0.122935
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.122833
ESX1 ESX homeobox 1 0.122703
SRSF1 serine/arginine-rich splicing factor 1 0.122361
ANGPTL1 angiopoietin-like 1 0.122255
PFKM phosphofructokinase, muscle 0.122147
FMNL2 formin-like 2 0.122065
ULBP3 UL16 binding protein 3 0.121956
SLAMF6 SLAM family member 6 0.121817
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.12179
HECA headcase homolog (Drosophila) 0.121566
XCL1 chemokine (C motif) ligand 1 0.121251
PRNT prion protein (testis specific) 0.121164
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.120989
PI3 peptidase inhibitor 3, skin-derived 0.120899
CD300A CD300a molecule 0.12075
HMGB1 high mobility group box 1 0.120569