mhc class ii protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. (Gene Ontology, GO_0042613)
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Genes

226 proteins co-occuring with the mhc class ii protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD86 CD86 molecule 3.14348
CD80 CD80 molecule 2.76241
CD4 CD4 molecule 2.73059
CIITA class II, major histocompatibility complex, transactivator 2.6199
CD40 CD40 molecule, TNF receptor superfamily member 5 2.56184
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.96638
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.83406
CD83 CD83 molecule 1.74829
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.66901
HLA-DMA major histocompatibility complex, class II, DM alpha 1.64733
RFXAP regulatory factor X-associated protein 1.63539
ICAM1 intercellular adhesion molecule 1 1.52371
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.49775
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 1.43669
FOXP3 forkhead box P3 1.4153
LY75 lymphocyte antigen 75 1.40802
CD276 CD276 molecule 1.39851
CCR7 chemokine (C-C motif) receptor 7 1.3896
HLA-B major histocompatibility complex, class I, B 1.35758
RFX1 regulatory factor X, 1 (influences HLA class II expression) 1.35704
RFXANK regulatory factor X-associated ankyrin-containing protein 1.35047
TLR4 toll-like receptor 4 1.23452
TLR2 toll-like receptor 2 1.19931
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.1516
AIF1 allograft inflammatory factor 1 1.14494
CD207 CD207 molecule, langerin 1.14239
CD19 CD19 molecule 1.09951
ZBTB7B zinc finger and BTB domain containing 7B 1.099
EDA ectodysplasin A 1.08628
TNF tumor necrosis factor 1.06094
CD1D CD1d molecule 1.06044
SIRPA signal-regulatory protein alpha 1.05993
CD68 CD68 molecule 1.05993
CD5 CD5 molecule 1.03479
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.00892
IL1B interleukin 1, beta 1.00645
CD40LG CD40 ligand 1.00202
ZXDC ZXD family zinc finger C 0.983419
CD69 CD69 molecule 0.973714
CD44 CD44 molecule (Indian blood group) 0.954483
CD163 CD163 molecule 0.936905
TLR9 toll-like receptor 9 0.935016
CD1C CD1c molecule 0.934544
IL4 interleukin 4 0.920449
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.914842
STAT1 signal transducer and activator of transcription 1, 91kDa 0.906926
MYD88 myeloid differentiation primary response 88 0.901353
MOG myelin oligodendrocyte glycoprotein 0.899962
CCR2 chemokine (C-C motif) receptor 2 0.89348
LAG3 lymphocyte-activation gene 3 0.886551
FOXN1 forkhead box N1 0.885166
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.873186
ZXDA zinc finger, X-linked, duplicated A 0.863988
IL10 interleukin 10 0.858473
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.848828
CD1B CD1b molecule 0.841023
CD200 CD200 molecule 0.833679
HLA-C major histocompatibility complex, class I, C 0.818993
FLT3 fms-related tyrosine kinase 3 0.817616
IL2 interleukin 2 0.813946
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 0.808441
THY1 Thy-1 cell surface antigen 0.799728
CD209 CD209 molecule 0.777298
ITGAD integrin, alpha D 0.770907
MRC1 mannose receptor, C type 1 0.760433
CD8A CD8a molecule 0.736464
MBP myelin basic protein 0.719015
FER fer (fps/fes related) tyrosine kinase 0.706156
CCL2 chemokine (C-C motif) ligand 2 0.692955
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.674196
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.662935
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.660345
IDO1 indoleamine 2,3-dioxygenase 1 0.64958
VCAM1 vascular cell adhesion molecule 1 0.635868
CXCL10 chemokine (C-X-C motif) ligand 10 0.624355
CD79A CD79a molecule, immunoglobulin-associated alpha 0.622229
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.617982
LAMP1 lysosomal-associated membrane protein 1 0.616285
LYZ lysozyme 0.608663
CD34 CD34 molecule 0.607395
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.606128
ARG1 arginase 1 0.600223
CCL21 chemokine (C-C motif) ligand 21 0.599381
PTPRC protein tyrosine phosphatase, receptor type, C 0.596855
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.596014
TGFB1 transforming growth factor, beta 1 0.588456
IRF1 interferon regulatory factor 1 0.582176
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.577999
SPPL2A signal peptide peptidase like 2A 0.575912
TSPO translocator protein (18kDa) 0.574244
S100A9 S100 calcium binding protein A9 0.568416
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.564262
DCT dopachrome tautomerase 0.562602
IFNA1 interferon, alpha 1 0.554318
MRPL33 mitochondrial ribosomal protein L33 0.553905
GJB6 gap junction protein, beta 6, 30kDa 0.545236
AIRE autoimmune regulator 0.545236
CCL19 chemokine (C-C motif) ligand 19 0.532078
CD200R1 CD200 receptor 1 0.529618
IFNG interferon, gamma 0.526341
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.523476
TLR3 toll-like receptor 3 0.510418
IRF4 interferon regulatory factor 4 0.509604
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.503506
CTSS cathepsin S 0.503099
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.502288
B2M beta-2-microglobulin 0.496205
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.493371
IL12B interleukin 12B 0.488519
ZBTB46 zinc finger and BTB domain containing 46 0.485289
PRDM1 PR domain containing 1, with ZNF domain 0.48005
CCL3 chemokine (C-C motif) ligand 3 0.478038
NELFCD negative elongation factor complex member C/D 0.474822
CCL22 chemokine (C-C motif) ligand 22 0.466399
RETNLB resistin like beta 0.462398
HLA-E major histocompatibility complex, class I, E 0.459203
ZCCHC7 zinc finger, CCHC domain containing 7 0.458404
BCR breakpoint cluster region 0.457208
HLA-A major histocompatibility complex, class I, A 0.45641
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.45641
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.455613
SOCS1 suppressor of cytokine signaling 1 0.454816
IL17A interleukin 17A 0.448451
PRF1 perforin 1 (pore forming protein) 0.447656
IL6 interleukin 6 0.446069
BTNL2 butyrophilin-like 2 0.442896
CD9 CD9 molecule 0.438146
CD274 CD274 molecule 0.434985
IL2RA interleukin 2 receptor, alpha 0.422389
IL1A interleukin 1, alpha 0.400139
TFRC transferrin receptor 0.395873
IRAK3 interleukin-1 receptor-associated kinase 3 0.393162
NOS2 nitric oxide synthase 2, inducible 0.390455
CFAP70 cilia and flagella associated protein 70 0.388137
FUT2 fucosyltransferase 2 (secretor status included) 0.380045
FASLG Fas ligand (TNF superfamily, member 6) 0.375818
MSR1 macrophage scavenger receptor 1 0.374666
SLC46A2 solute carrier family 46, member 2 0.373516
TSHR thyroid stimulating hormone receptor 0.37045
CD8B CD8b molecule 0.367771
TREM1 triggering receptor expressed on myeloid cells 1 0.366241
TRAC T cell receptor alpha constant 0.363567
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.363185
CXCL9 chemokine (C-X-C motif) ligand 9 0.361659
GFAP glial fibrillary acidic protein 0.357847
NCR1 natural cytotoxicity triggering receptor 1 0.349863
CCL5 chemokine (C-C motif) ligand 5 0.344556
PMEL premelanosome protein 0.343042
LUM lumican 0.335487
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.334356
RAG2 recombination activating gene 2 0.32345
IRF2 interferon regulatory factor 2 0.323075
IL23A interleukin 23, alpha subunit p19 0.318953
SPATA19 spermatogenesis associated 19 0.31783
CD48 CD48 molecule 0.31596
TSLP thymic stromal lymphopoietin 0.309986
TBX21 T-box 21 0.309613
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.307377
CD81 CD81 molecule 0.304771
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.300682
CD53 CD53 molecule 0.299569
CD37 CD37 molecule 0.299197
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.296972
RAG1 recombination activating gene 1 0.294378
NCAM1 neural cell adhesion molecule 1 0.290308
PDCD1LG2 programmed cell death 1 ligand 2 0.285507
GMEB2 glucocorticoid modulatory element binding protein 2 0.284032
ARL14 ADP-ribosylation factor-like 14 0.275569
CTCF CCCTC-binding factor (zinc finger protein) 0.269701
CD38 CD38 molecule 0.266774
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.264946
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.262755
CD63 CD63 molecule 0.259837
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.25547
CD58 CD58 molecule 0.251839
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.251114
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.250389
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.24894
IFNGR1 interferon gamma receptor 1 0.245323
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.245323
TG thyroglobulin 0.22385
CD24 CD24 molecule 0.220673
HLA-DOA major histocompatibility complex, class II, DO alpha 0.220321
CD82 CD82 molecule 0.218914
CCL25 chemokine (C-C motif) ligand 25 0.21681
GATA3 GATA binding protein 3 0.212974
LTA lymphotoxin alpha 0.209169
CLEC2D C-type lectin domain family 2, member D 0.201335
IL19 interleukin 19 0.201335
SELL selectin L 0.199659
CXCR3 chemokine (C-X-C motif) receptor 3 0.199325
HLA-DMB major histocompatibility complex, class II, DM beta 0.198325
CSF1R colony stimulating factor 1 receptor 0.196669
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.195353
CARD17 caspase recruitment domain family, member 17 0.194698
CCR6 chemokine (C-C motif) receptor 6 0.191777
ICAM3 intercellular adhesion molecule 3 0.190175
HBA1 hemoglobin, alpha 1 0.189222
BTNL9 butyrophilin-like 9 0.186397
CD22 CD22 molecule 0.185777
GYPC glycophorin C (Gerbich blood group) 0.18516
HBA2 hemoglobin, alpha 2 0.184547
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.183328
CD79B CD79b molecule, immunoglobulin-associated beta 0.178588
RUNX3 runt-related transcription factor 3 0.177154
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.176305
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.176024
TLR6 toll-like receptor 6 0.176024
JAK1 Janus kinase 1 0.175188
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.172468
TLR7 toll-like receptor 7 0.17141
ANGPTL1 angiopoietin-like 1 0.169099
VEGFA vascular endothelial growth factor A 0.167856
IRF7 interferon regulatory factor 7 0.167125
MARCH9 membrane-associated ring finger (C3HC4) 9 0.166167
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.166167
CTSD cathepsin D 0.165231
HECA headcase homolog (Drosophila) 0.1632
PARK2 parkin RBR E3 ubiquitin protein ligase 0.162117
IL17F interleukin 17F 0.161905
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 0.161693
PRNT prion protein (testis specific) 0.160254
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.159074
HMGB1 high mobility group box 1 0.156513
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.156342
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.156342