mhc class i protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules. (Gene Ontology, GO_0042612)
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226 proteins co-occuring with the mhc class i protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 2.89059
CD4 CD4 molecule 2.02566
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 1.9084
CD86 CD86 molecule 1.78781
CD80 CD80 molecule 1.75531
HLA-A major histocompatibility complex, class I, A 1.66901
B2M beta-2-microglobulin 1.50904
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.45364
CD40 CD40 molecule, TNF receptor superfamily member 5 1.4446
ICAM1 intercellular adhesion molecule 1 1.36802
TAPBP TAP binding protein (tapasin) 1.34556
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 1.33304
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.29799
HLA-E major histocompatibility complex, class I, E 1.29103
MICA MHC class I polypeptide-related sequence A 1.27664
CD1D CD1d molecule 1.13727
DHDH dihydrodiol dehydrogenase (dimeric) 1.09696
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.00596
KLRC1 killer cell lectin-like receptor subfamily C, member 1 1.00153
ERAP1 endoplasmic reticulum aminopeptidase 1 0.992693
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.981473
PACS1 phosphofurin acidic cluster sorting protein 1 0.97953
HLA-G major histocompatibility complex, class I, G 0.95831
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.950189
HLA-C major histocompatibility complex, class I, C 0.929363
IFNA1 interferon, alpha 1 0.899962
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.893943
CD83 CD83 molecule 0.885628
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.868126
CIITA class II, major histocompatibility complex, transactivator 0.800645
HCG4P11 HLA complex group 4 pseudogene 11 0.797895
HLA-F major histocompatibility complex, class I, F 0.797895
CD1C CD1c molecule 0.789649
NCR1 natural cytotoxicity triggering receptor 1 0.789649
CS citrate synthase 0.782326
CD40LG CD40 ligand 0.773188
CD276 CD276 molecule 0.756345
CD69 CD69 molecule 0.755437
CD58 CD58 molecule 0.755437
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.746381
PRF1 perforin 1 (pore forming protein) 0.744122
HFE hemochromatosis 0.713682
CCR7 chemokine (C-C motif) receptor 7 0.710136
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.702185
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.682027
RAE1 ribonucleic acid export 1 0.678108
CD44 CD44 molecule (Indian blood group) 0.676803
PMEL premelanosome protein 0.67246
TLR4 toll-like receptor 4 0.672026
FOXP3 forkhead box P3 0.664232
TLR2 toll-like receptor 2 0.650869
ZBTB7B zinc finger and BTB domain containing 7B 0.646574
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.641001
MEX3C mex-3 RNA binding family member C 0.63544
TNF tumor necrosis factor 0.634159
ARF6 ADP-ribosylation factor 6 0.631598
MICB MHC class I polypeptide-related sequence B 0.628187
TLR9 toll-like receptor 9 0.623504
FGF6 fibroblast growth factor 6 0.610355
CALR calreticulin 0.602331
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.596435
EDA ectodysplasin A 0.590133
TRAC T cell receptor alpha constant 0.588875
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.565092
TFRC transferrin receptor 0.564677
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.563017
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.555145
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 0.550599
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.548122
STAT1 signal transducer and activator of transcription 1, 91kDa 0.546472
MYD88 myeloid differentiation primary response 88 0.531258
IL1B interleukin 1, beta 0.528798
CD1B CD1b molecule 0.525931
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.515716
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.514085
IRF1 interferon regulatory factor 1 0.505131
CD48 CD48 molecule 0.504318
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 0.490539
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.488115
MYBPC1 myosin binding protein C, slow type 0.487711
LAMP1 lysosomal-associated membrane protein 1 0.487307
IL2 interleukin 2 0.485289
CD247 CD247 molecule 0.47844
DERL1 derlin 1 0.478038
TYROBP TYRO protein tyrosine kinase binding protein 0.474822
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.473617
NCAM1 neural cell adhesion molecule 1 0.472011
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.468401
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.461599
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.4608
PLA2G4E phospholipase A2, group IVE 0.458404
MRC1 mannose receptor, C type 1 0.456809
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.452029
IGF1 insulin-like growth factor 1 (somatomedin C) 0.44052
SPATA19 spermatogenesis associated 19 0.439728
HSPA4 heat shock 70kDa protein 4 0.439728
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.431829
LCK LCK proto-oncogene, Src family tyrosine kinase 0.425138
CD300C CD300c molecule 0.420428
NLRC5 NLR family, CARD domain containing 5 0.413382
CANX calnexin 0.412601
SIRPA signal-regulatory protein alpha 0.393549
VCAM1 vascular cell adhesion molecule 1 0.385051
UBASH3A ubiquitin associated and SH3 domain containing A 0.383124
CXCL10 chemokine (C-X-C motif) ligand 10 0.381584
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase 0.377738
HCK HCK proto-oncogene, Src family tyrosine kinase 0.369301
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.369301
PACS2 phosphofurin acidic cluster sorting protein 2 0.364713
MYF6 myogenic factor 6 (herculin) 0.363185
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.362422
IDO1 indoleamine 2,3-dioxygenase 1 0.360515
IL15 interleukin 15 0.359752
TIGIT T cell immunoreceptor with Ig and ITIM domains 0.349105
CD59 CD59 molecule, complement regulatory protein 0.347208
UBE2J2 ubiquitin-conjugating enzyme E2, J2 0.345692
TGFB1 transforming growth factor, beta 1 0.344556
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.343421
IFNG interferon, gamma 0.341529
TSPO translocator protein (18kDa) 0.338506
DNAH8 dynein, axonemal, heavy chain 8 0.338506
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.335487
PARK2 parkin RBR E3 ubiquitin protein ligase 0.332848
TLR3 toll-like receptor 3 0.329084
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.328708
LY75 lymphocyte antigen 75 0.328332
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.326078
NKG7 natural killer cell granule protein 7 0.323825
CYTH3 cytohesin 3 0.322325
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.315586
RAG1 recombination activating gene 1 0.315586
CD34 CD34 molecule 0.310358
ULBP1 UL16 binding protein 1 0.305888
IL2RA interleukin 2 receptor, alpha 0.304027
CD1E CD1e molecule 0.302912
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.297342
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.296601
IL6 interleukin 6 0.291047
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.288829
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.28846
IFNB1 interferon, beta 1, fibroblast 0.285507
FURIN furin (paired basic amino acid cleaving enzyme) 0.284769
BSG basigin (Ok blood group) 0.278141
FASLG Fas ligand (TNF superfamily, member 6) 0.276304
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.274101
DPPA5 developmental pluripotency associated 5 0.273734
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.272267
MARCH9 membrane-associated ring finger (C3HC4) 9 0.271533
PVRL3 poliovirus receptor-related 3 0.270068
RAG2 recombination activating gene 2 0.268603
OASL 2'-5'-oligoadenylate synthetase-like 0.265311
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.26312
MLANA melan-A 0.258745
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.257289
NLRP10 NLR family, pyrin domain containing 10 0.255107
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.250026
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.24894
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.24424
IL17F interleukin 17F 0.236324
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 0.235966
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.235249
ICAM2 intercellular adhesion molecule 2 0.233459
CD68 CD68 molecule 0.232029
IL10 interleukin 10 0.229532
CTAG2 cancer/testis antigen 2 0.228108
LAG3 lymphocyte-activation gene 3 0.226686
BAGE2 B melanoma antigen family, member 2 0.226331
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.225976
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.220673
CD8A CD8a molecule 0.219969
TLR7 toll-like receptor 7 0.218563
BAG5 BCL2-associated athanogene 5 0.215412
MCOLN2 mucolipin 2 0.211587
MAGEA3 melanoma antigen family A3 0.210549
MSTN myostatin 0.210203
WARS tryptophanyl-tRNA synthetase 0.210203
CXCL9 chemokine (C-X-C motif) ligand 9 0.209858
PARP9 poly (ADP-ribose) polymerase family, member 9 0.208481
GAS7 growth arrest-specific 7 0.206423
HLX H2.0-like homeobox 0.204718
IL17RA interleukin 17 receptor A 0.202009
IL23R interleukin 23 receptor 0.201672
GJB6 gap junction protein, beta 6, 30kDa 0.199993
MX1 MX dynamin-like GTPase 1 0.197993
MT1E metallothionein 1E 0.196999
COX5B cytochrome c oxidase subunit Vb 0.195681
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.195353
MOG myelin oligodendrocyte glycoprotein 0.195025
MAGEC1 melanoma antigen family C1 0.19307
CD5 CD5 molecule 0.191456
CLEC9A C-type lectin domain family 9, member A 0.191456
MCM8 minichromosome maintenance complex component 8 0.191135
THY1 Thy-1 cell surface antigen 0.188905
HADH hydroxyacyl-CoA dehydrogenase 0.187646
NLRP4 NLR family, pyrin domain containing 4 0.186397
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.185469
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.184853
SKIL SKI-like proto-oncogene 0.183631
PDPN podoplanin 0.183025
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.180045
MRAP melanocortin 2 receptor accessory protein 0.178299
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.174911
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.174911
ESX1 ESX homeobox 1 0.173543
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.171937
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.17141
SRSF1 serine/arginine-rich splicing factor 1 0.170114
LTA lymphotoxin alpha 0.16935
CD19 CD19 molecule 0.169099
PFKM phosphofructokinase, muscle 0.168101
FMNL2 formin-like 2 0.167366
ULBP3 UL16 binding protein 3 0.166405
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.165932
SLAMF6 SLAM family member 6 0.165231
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.165
HLA-DMA major histocompatibility complex, class II, DM alpha 0.164089
CD81 CD81 molecule 0.163865
JAK3 Janus kinase 3 0.162763
CD209 CD209 molecule 0.161905
SELE selectin E 0.161693
XCL1 chemokine (C motif) ligand 1 0.160863
ICAM3 intercellular adhesion molecule 3 0.159462
AIF1 allograft inflammatory factor 1 0.159268
PI3 peptidase inhibitor 3, skin-derived 0.158502
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.158129
CD300A CD300a molecule 0.157578