mhc class i peptide loading complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. (Gene Ontology, GO_0042824)
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Genes

4 proteins localized to the mhc class i peptide loading complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.663342
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.663342
TAPBP TAP binding protein (tapasin) 0.663342
CALR calreticulin 0.098109