metoclopramide-2353 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the metoclopramide-2353 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADGB androglobin
ADGRD2 adhesion G protein-coupled receptor D2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMPD2 adenosine monophosphate deaminase 2
APOLD1 apolipoprotein L domain containing 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
B3GAT3 beta-1,3-glucuronyltransferase 3
BIN1 bridging integrator 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CEP350 centrosomal protein 350kDa
CGA glycoprotein hormones, alpha polypeptide
CLTA clathrin, light chain A
CORO1B coronin, actin binding protein, 1B
CRABP2 cellular retinoic acid binding protein 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DENND5B DENN/MADD domain containing 5B
DUSP6 dual specificity phosphatase 6
EFNA5 ephrin-A5
EMC1 ER membrane protein complex subunit 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLRA1 glycine receptor, alpha 1
GPR37L1 G protein-coupled receptor 37 like 1
HOXD13 homeobox D13
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IGLJ3 immunoglobulin lambda joining 3
INF2 inverted formin, FH2 and WH2 domain containing
IQCK IQ motif containing K
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
LINC00597 long intergenic non-protein coding RNA 597
LOC100287590 uncharacterized LOC100287590
MAP4 microtubule-associated protein 4
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPM3 nucleophosmin/nucleoplasmin 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11X protocadherin 11 X-linked
PLCG1 phospholipase C, gamma 1
PLIN2 perilipin 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PVT1 Pvt1 oncogene (non-protein coding)
RAB11B RAB11B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RBM19 RNA binding motif protein 19
RBM8A RNA binding motif protein 8A
REST RE1-silencing transcription factor
RGS9 regulator of G-protein signaling 9
RIN3 Ras and Rab interactor 3
RNASE3 ribonuclease, RNase A family, 3
RNF19B ring finger protein 19B
SEC23IP SEC23 interacting protein
SECISBP2L SECIS binding protein 2-like
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFTPB surfactant protein B
SH3BP1 SH3-domain binding protein 1
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SKI SKI proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35E2 solute carrier family 35, member E2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SPEN spen family transcriptional repressor
SRRM2 serine/arginine repetitive matrix 2
SYNJ2 synaptojanin 2
SYTL2 synaptotagmin-like 2
TLN2 talin 2
TMC5 transmembrane channel-like 5
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM49 tripartite motif containing 49
TTLL1 tubulin tyrosine ligase-like family member 1
UGCG UDP-glucose ceramide glucosyltransferase
USP11 ubiquitin specific peptidase 11
VWA5A von Willebrand factor A domain containing 5A
ZBTB38 zinc finger and BTB domain containing 38
ZBTB40 zinc finger and BTB domain containing 40
ZC3H7B zinc finger CCCH-type containing 7B
ZNF124 zinc finger protein 124
ZNF43 zinc finger protein 43
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAG4 BCL2-associated athanogene 4
BST2 bone marrow stromal cell antigen 2
BTK Bruton agammaglobulinemia tyrosine kinase
C4ORF29 chromosome 4 open reading frame 29
CAPN1 calpain 1, (mu/I) large subunit
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
DCTN4 dynactin 4 (p62)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DTX4 deltex 4, E3 ubiquitin ligase
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERP29 endoplasmic reticulum protein 29
EXOC5 exocyst complex component 5
FBXW12 F-box and WD repeat domain containing 12
GAR1 GAR1 ribonucleoprotein
GDE1 glycerophosphodiester phosphodiesterase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR22 G protein-coupled receptor 22
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HELLS helicase, lymphoid-specific
HIST1H1C histone cluster 1, H1c
HIST1H2BF histone cluster 1, H2bf
HNRNPF heterogeneous nuclear ribonucleoprotein F
HYAL2 hyaluronoglucosaminidase 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
KCTD15 potassium channel tetramerization domain containing 15
KIF3B kinesin family member 3B
LMAN1 lectin, mannose-binding, 1
LRRC37A3 leucine rich repeat containing 37, member A3
MAVS mitochondrial antiviral signaling protein
MBTD1 mbt domain containing 1
METTL2B methyltransferase like 2B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR11 myotubularin related protein 11
NMD3 NMD3 ribosome export adaptor
NOL12 nucleolar protein 12
PHACTR4 phosphatase and actin regulator 4
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMVK phosphomevalonate kinase
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSAT1 phosphoserine aminotransferase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
SDF2L1 stromal cell-derived factor 2-like 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMAD7 SMAD family member 7
SNIP1 Smad nuclear interacting protein 1
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPATA7 spermatogenesis associated 7
SPP1 secreted phosphoprotein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
U2AF1 U2 small nuclear RNA auxiliary factor 1
UEVLD UEV and lactate/malate dehyrogenase domains
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF160 zinc finger protein 160
ZNF227 zinc finger protein 227
ZNF264 zinc finger protein 264
ZNF273 zinc finger protein 273
ZNF33B zinc finger protein 33B
ZNF426 zinc finger protein 426
ZNF586 zinc finger protein 586
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF654 zinc finger protein 654
ZNF721 zinc finger protein 721
ZNF91 zinc finger protein 91