meticrane-7282 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the meticrane-7282 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMBRA1 autophagy/beclin-1 regulator 1
AMPD3 adenosine monophosphate deaminase 3
APOL6 apolipoprotein L, 6
ARL15 ADP-ribosylation factor-like 15
ARTN artemin
ATAT1 alpha tubulin acetyltransferase 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF79 chromosome 14 open reading frame 79
C1ORF21 chromosome 1 open reading frame 21
CA9 carbonic anhydrase IX
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNO cyclin O
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CNTNAP2 contactin associated protein-like 2
CPNE7 copine VII
CREBBP CREB binding protein
CTNND2 catenin (cadherin-associated protein), delta 2
DAGLA diacylglycerol lipase, alpha
DENND2A DENN/MADD domain containing 2A
DENND2D DENN/MADD domain containing 2D
DENND4A DENN/MADD domain containing 4A
DOK4 docking protein 4
E2F4 E2F transcription factor 4, p107/p130-binding
EDDM3B epididymal protein 3B
EGFR epidermal growth factor receptor
EXD3 exonuclease 3'-5' domain containing 3
F5 coagulation factor V (proaccelerin, labile factor)
GLS2 glutaminase 2 (liver, mitochondrial)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCA2A guanylate cyclase activator 2A (guanylin)
HDAC11 histone deacetylase 11
HFE hemochromatosis
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC100131532 uncharacterized LOC100131532
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP1 low density lipoprotein receptor-related protein 1
LRRK1 leucine-rich repeat kinase 1
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARS methionyl-tRNA synthetase
METTL7A methyltransferase like 7A
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MPPE1 metallophosphoesterase 1
MTRF1L mitochondrial translational release factor 1-like
MYL10 myosin, light chain 10, regulatory
MYOZ3 myozenin 3
NCAPH2 non-SMC condensin II complex, subunit H2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKP3 plakophilin 3
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB6A RAB6A, member RAS oncogene family
RABIF RAB interacting factor
RAD51 RAD51 recombinase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCN1B sodium channel, voltage gated, type I beta subunit
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SENP6 SUMO1/sentrin specific peptidase 6
SFTPB surfactant protein B
SIAH1 siah E3 ubiquitin protein ligase 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC35F6 solute carrier family 35, member F6
SLC35G2 solute carrier family 35, member G2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMO smoothened, frizzled class receptor
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPTB spectrin, beta, erythrocytic
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBRG4 transforming growth factor beta regulator 4
TBXA2R thromboxane A2 receptor
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM63A transmembrane protein 63A
TSSK2 testis-specific serine kinase 2
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VARS valyl-tRNA synthetase
WDR25 WD repeat domain 25
ZHX3 zinc fingers and homeoboxes 3
ZNF234 zinc finger protein 234
ZNF44 zinc finger protein 44
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ASB13 ankyrin repeat and SOCS box containing 13
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
C16ORF45 chromosome 16 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CBX7 chromobox homolog 7
CCDC47 coiled-coil domain containing 47
CENPT centromere protein T
CEP70 centrosomal protein 70kDa
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYL1 crystallin, lambda 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAZAP1 DAZ associated protein 1
DCAF13 DDB1 and CUL4 associated factor 13
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK1 delta-like 1 homolog (Drosophila)
ELOVL4 ELOVL fatty acid elongase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA4 EPH receptor A4
EVPL envoplakin
FAM131B family with sequence similarity 131, member B
FANCF Fanconi anemia, complementation group F
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXC1 forkhead box C1
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GALNS galactosamine (N-acetyl)-6-sulfatase
GLCE glucuronic acid epimerase
GMIP GEM interacting protein
GPALPP1 GPALPP motifs containing 1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GUSBP3 glucuronidase, beta pseudogene 3
HLX H2.0-like homeobox
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI6 interferon, alpha-inducible protein 6
IRF6 interferon regulatory factor 6
JUNB jun B proto-oncogene
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIRREL kin of IRRE like (Drosophila)
KLK6 kallikrein-related peptidase 6
KPTN kaptin (actin binding protein)
KRT4 keratin 4, type II
MAGEA6 melanoma antigen family A6
MAPK12 mitogen-activated protein kinase 12
MEIS3P1 Meis homeobox 3 pseudogene 1
METTL2B methyltransferase like 2B
MFSD11 major facilitator superfamily domain containing 11
MYLK myosin light chain kinase
NABP2 nucleic acid binding protein 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOL6 nucleolar protein 6 (RNA-associated)
NT5DC3 5'-nucleotidase domain containing 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD3 OTU deubiquitinase 3
PALMD palmdelphin
PCOLCE procollagen C-endopeptidase enhancer
PCSK7 proprotein convertase subtilisin/kexin type 7
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC1 placenta-specific 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNRC1 proline-rich nuclear receptor coactivator 1
PORCN porcupine homolog (Drosophila)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHOB ras homolog family member B
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPL13P5 ribosomal protein L13 pseudogene 5
SETD1B SET domain containing 1B
SETD6 SET domain containing 6
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX12 SRY (sex determining region Y)-box 12
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAR steroidogenic acute regulatory protein
STBD1 starch binding domain 1
TGIF2 TGFB-induced factor homeobox 2
THBS3 thrombospondin 3
TMEM132A transmembrane protein 132A
TMEM156 transmembrane protein 156
TMEM2 transmembrane protein 2
TOR4A torsin family 4, member A
TRIM66 tripartite motif containing 66
TSKU tsukushi, small leucine rich proteoglycan
USP27X ubiquitin specific peptidase 27, X-linked
WDR91 WD repeat domain 91
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF34 zinc finger protein 34
ZNF562 zinc finger protein 562