methocarbamol-7467 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the methocarbamol-7467 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANTXR1 anthrax toxin receptor 1
AOX1 aldehyde oxidase 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AQP3 aquaporin 3 (Gill blood group)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAIAP2 BAI1-associated protein 2
BFSP1 beaded filament structural protein 1, filensin
C1ORF61 chromosome 1 open reading frame 61
CALML3 calmodulin-like 3
CBX7 chromobox homolog 7
CD248 CD248 molecule, endosialin
CD70 CD70 molecule
CD80 CD80 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CORT cortistatin
CUZD1 CUB and zona pellucida-like domains 1
DVL3 dishevelled segment polarity protein 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPN1 epsin 1
EVA1B eva-1 homolog B (C. elegans)
GADD45B growth arrest and DNA-damage-inducible, beta
GAMT guanidinoacetate N-methyltransferase
GAP43 growth associated protein 43
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-C major histocompatibility complex, class I, C
IGFBP3 insulin-like growth factor binding protein 3
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
IQCK IQ motif containing K
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA8 integrin, alpha 8
KLF6 Kruppel-like factor 6
LARP7 La ribonucleoprotein domain family, member 7
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM4 MDM4, p53 regulator
MID1 midline 1
MLX MLX, MAX dimerization protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NAAA N-acylethanolamine acid amidase
NCOA2 nuclear receptor coactivator 2
NELL2 NEL-like 2 (chicken)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NINL ninein-like
NREP neuronal regeneration related protein
NUP62CL nucleoporin 62kDa C-terminal like
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PIDD1 p53-induced death domain protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP5C protein phosphatase 5, catalytic subunit
PSD4 pleckstrin and Sec7 domain containing 4
QTRT1 queuine tRNA-ribosyltransferase 1
RAB30 RAB30, member RAS oncogene family
RANBP3 RAN binding protein 3
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RREB1 ras responsive element binding protein 1
S100A8 S100 calcium binding protein A8
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNTA1 syntrophin, alpha 1
STX2 syntaxin 2
TADA3 transcriptional adaptor 3
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM121 transmembrane protein 121
TMEM53 transmembrane protein 53
TP53I11 tumor protein p53 inducible protein 11
TRAK1 trafficking protein, kinesin binding 1
TRIM10 tripartite motif containing 10
TRIP11 thyroid hormone receptor interactor 11
TRMT61A tRNA methyltransferase 61A
TTC38 tetratricopeptide repeat domain 38
TTLL5 tubulin tyrosine ligase-like family member 5
WDR91 WD repeat domain 91
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY1 YY1 transcription factor
YY2 YY2 transcription factor
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
AKR1C3 aldo-keto reductase family 1, member C3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATAD5 ATPase family, AAA domain containing 5
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BAX BCL2-associated X protein
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C11ORF95 chromosome 11 open reading frame 95
C17ORF70 chromosome 17 open reading frame 70
C21ORF91 chromosome 21 open reading frame 91
CD82 CD82 molecule
CFD complement factor D (adipsin)
CLASRP CLK4-associating serine/arginine rich protein
COBL cordon-bleu WH2 repeat protein
CORO2A coronin, actin binding protein, 2A
DCAF13 DDB1 and CUL4 associated factor 13
DCP1A decapping mRNA 1A
DOCK1 dedicator of cytokinesis 1
DVL1 dishevelled segment polarity protein 1
ELMO3 engulfment and cell motility 3
ERCC5 excision repair cross-complementation group 5
FAM118A family with sequence similarity 118, member A
FAM189A2 family with sequence similarity 189, member A2
FAM222B family with sequence similarity 222, member B
FGGY FGGY carbohydrate kinase domain containing
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HDAC4 histone deacetylase 4
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HOXA5 homeobox A5
HP1BP3 heterochromatin protein 1, binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IL17RA interleukin 17 receptor A
IPO8 importin 8
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00115 long intergenic non-protein coding RNA 115
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAPK12 mitogen-activated protein kinase 12
MBNL3 muscleblind-like splicing regulator 3
MTCL1 microtubule crosslinking factor 1
N4BP3 NEDD4 binding protein 3
NCAM2 neural cell adhesion molecule 2
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
PAIP2B poly(A) binding protein interacting protein 2B
PARP12 poly (ADP-ribose) polymerase family, member 12
PER3 period circadian clock 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
RAB33B RAB33B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
SCD5 stearoyl-CoA desaturase 5
SLC35F5 solute carrier family 35, member F5
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SREK1IP1 SREK1-interacting protein 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TEAD3 TEA domain family member 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM127 transmembrane protein 127
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPST1 tyrosylprotein sulfotransferase 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSSC4 tumor suppressing subtransferable candidate 4
TTC23 tetratricopeptide repeat domain 23
VEGFC vascular endothelial growth factor C
ZNF16 zinc finger protein 16
ZNF184 zinc finger protein 184
ZNF286A zinc finger protein 286A
ZNF365 zinc finger protein 365
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701
ZNF8 zinc finger protein 8