methapyrilene-3205 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the methapyrilene-3205 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM12 ADAM metallopeptidase domain 12
ADAM7 ADAM metallopeptidase domain 7
ADGRE3 adhesion G protein-coupled receptor E3
ADGRL3 adhesion G protein-coupled receptor L3
ADRB1 adrenoceptor beta 1
AHCYL1 adenosylhomocysteinase-like 1
ALDOB aldolase B, fructose-bisphosphate
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARSD arylsulfatase D
ATP10B ATPase, class V, type 10B
BAG4 BCL2-associated athanogene 4
BCAM basal cell adhesion molecule (Lutheran blood group)
BMP1 bone morphogenetic protein 1
CABIN1 calcineurin binding protein 1
CARD10 caspase recruitment domain family, member 10
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL19 chemokine (C-C motif) ligand 19
CCNO cyclin O
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLIP2 CAP-GLY domain containing linker protein 2
COL6A1 collagen, type VI, alpha 1
COMT catechol-O-methyltransferase
DOK4 docking protein 4
DUSP9 dual specificity phosphatase 9
DVL3 dishevelled segment polarity protein 3
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
ELSPBP1 epididymal sperm binding protein 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EXPH5 exophilin 5
FAXDC2 fatty acid hydroxylase domain containing 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHOD1 formin homology 2 domain containing 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLDC glycine dehydrogenase (decarboxylating)
GLRX3 glutaredoxin 3
GPR75 G protein-coupled receptor 75
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GYG2 glycogenin 2
HOXA3 homeobox A3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RN interleukin 1 receptor antagonist
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIAA0125 KIAA0125
KIF1C kinesin family member 1C
KIF26B kinesin family member 26B
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMB4 laminin, beta 4
LHX1 LIM homeobox 1
LIMK1 LIM domain kinase 1
LOC157562 uncharacterized LOC157562
MAP2K5 mitogen-activated protein kinase kinase 5
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC3 myosin binding protein C, cardiac
MYOZ3 myozenin 3
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NKX3-2 NK3 homeobox 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGDHL oxoglutarate dehydrogenase-like
ORAI2 ORAI calcium release-activated calcium modulator 2
PAPOLA poly(A) polymerase alpha
PARVA parvin, alpha
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLLP plasmolipin
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM26 RNA binding motif protein 26
RHOBTB2 Rho-related BTB domain containing 2
RPL35A ribosomal protein L35a
RSG1 REM2 and RAB-like small GTPase 1
RUNX1 runt-related transcription factor 1
SETD1B SET domain containing 1B
SFTPB surfactant protein B
SLC35G2 solute carrier family 35, member G2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
STATH statherin
STEAP4 STEAP family member 4
SUN1 Sad1 and UNC84 domain containing 1
SYNJ2 synaptojanin 2
TLN1 talin 1
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM40 transmembrane protein 40
TRAF3IP3 TRAF3 interacting protein 3
TRBC1 T cell receptor beta constant 1
VAC14 Vac14 homolog (S. cerevisiae)
ZBTB7A zinc finger and BTB domain containing 7A
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP64 ZFP64 zinc finger protein
ZHX3 zinc fingers and homeoboxes 3
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
AMPD2 adenosine monophosphate deaminase 2
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOD apolipoprotein D
ARSB arylsulfatase B
ATAD5 ATPase family, AAA domain containing 5
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BTD biotinidase
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C17ORF80 chromosome 17 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
C22ORF46 chromosome 22 open reading frame 46
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC186 coiled-coil domain containing 186
CDON cell adhesion associated, oncogene regulated
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CST6 cystatin E/M
CXORF56 chromosome X open reading frame 56
DAGLA diacylglycerol lipase, alpha
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DPY19L1P1 DPY19L1 pseudogene 1
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPALPP1 GPALPP motifs containing 1
GPC3 glypican 3
GPR1 G protein-coupled receptor 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HIST1H1C histone cluster 1, H1c
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HIST1H2BM histone cluster 1, H2bm
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HOXC5 homeobox C5
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IL15RA interleukin 15 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
KCTD20 potassium channel tetramerization domain containing 20
KITLG KIT ligand
KIZ kizuna centrosomal protein
KLF3 Kruppel-like factor 3 (basic)
KLK5 kallikrein-related peptidase 5
LDHB lactate dehydrogenase B
LYZ lysozyme
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM4 MDM4, p53 regulator
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
MUC3A mucin 3A, cell surface associated
NEK11 NIMA-related kinase 11
NHEJ1 nonhomologous end-joining factor 1
NLRX1 NLR family member X1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPM3 nucleophosmin/nucleoplasmin 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PODNL1 podocan-like 1
PRR7 proline rich 7 (synaptic)
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
REEP4 receptor accessory protein 4
RGS20 regulator of G-protein signaling 20
RPL13P5 ribosomal protein L13 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A8 solute carrier family 12, member 8
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
STBD1 starch binding domain 1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF480 zinc finger protein 480
ZNF770 zinc finger protein 770