meteneprost-7557 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the meteneprost-7557 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ANGPTL4 angiopoietin-like 4
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
ARHGAP26 Rho GTPase activating protein 26
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARL14 ADP-ribosylation factor-like 14
AVPI1 arginine vasopressin-induced 1
AXL AXL receptor tyrosine kinase
BCORL1 BCL6 corepressor-like 1
BMP1 bone morphogenetic protein 1
C1ORF159 chromosome 1 open reading frame 159
C6ORF106 chromosome 6 open reading frame 106
CCNO cyclin O
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCN3 chloride channel, voltage-sensitive 3
CLDN3 claudin 3
COL2A1 collagen, type II, alpha 1
COL6A1 collagen, type VI, alpha 1
DAPK3 death-associated protein kinase 3
DCAF13 DDB1 and CUL4 associated factor 13
DHRS9 dehydrogenase/reductase (SDR family) member 9
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EXTL3 exostosin-like glycosyltransferase 3
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
FAM20B family with sequence similarity 20, member B
FAM214B family with sequence similarity 214, member B
GFOD2 glucose-fructose oxidoreductase domain containing 2
GNS glucosamine (N-acetyl)-6-sulfatase
GOSR2 golgi SNAP receptor complex member 2
GPC4 glypican 4
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRAMD1B GRAM domain containing 1B
HIC2 hypermethylated in cancer 2
HMGA1 high mobility group AT-hook 1
HOOK1 hook microtubule-tethering protein 1
IFI35 interferon-induced protein 35
IL1RL1 interleukin 1 receptor-like 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB4 integrin, beta 4
JAG2 jagged 2
KIAA1462 KIAA1462
LHFPL2 lipoma HMGIC fusion partner-like 2
LIG3 ligase III, DNA, ATP-dependent
LRRC40 leucine rich repeat containing 40
LYPD3 LY6/PLAUR domain containing 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MECOM MDS1 and EVI1 complex locus
MIA3 melanoma inhibitory activity family, member 3
MLH3 mutL homolog 3
MOB3B MOB kinase activator 3B
MRPS11 mitochondrial ribosomal protein S11
MRPS12 mitochondrial ribosomal protein S12
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NNT nicotinamide nucleotide transhydrogenase
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PDE10A phosphodiesterase 10A
PDE4A phosphodiesterase 4A, cAMP-specific
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCE1 phospholipase C, epsilon 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRDM2 PR domain containing 2, with ZNF domain
PRRC2B proline-rich coiled-coil 2B
PTGES prostaglandin E synthase
RPP25 ribonuclease P/MRP 25kDa subunit
RREB1 ras responsive element binding protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SDC2 syndecan 2
SETD4 SET domain containing 4
SETD8 SET domain containing (lysine methyltransferase) 8
SIM2 single-minded family bHLH transcription factor 2
SIX2 SIX homeobox 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOWAHC sosondowah ankyrin repeat domain family member C
SREBF2 sterol regulatory element binding transcription factor 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STX5 syntaxin 5
TLE3 transducin-like enhancer of split 3
TMEM132A transmembrane protein 132A
TRAK1 trafficking protein, kinesin binding 1
TRAPPC6A trafficking protein particle complex 6A
TTC17 tetratricopeptide repeat domain 17
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACVR1 activin A receptor, type I
ADCY6 adenylate cyclase 6
APH1A APH1A gamma secretase subunit
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARSJ arylsulfatase family, member J
BAX BCL2-associated X protein
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
CBS cystathionine-beta-synthase
CCDC69 coiled-coil domain containing 69
CD53 CD53 molecule
CDHR2 cadherin-related family member 2
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN6 chloride channel, voltage-sensitive 6
CNTNAP1 contactin associated protein 1
CST4 cystatin S
CTGF connective tissue growth factor
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DLL3 delta-like 3 (Drosophila)
EDIL3 EGF-like repeats and discoidin I-like domains 3
ESM1 endothelial cell-specific molecule 1
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAF1 Fas (TNFRSF6) associated factor 1
GAB2 GRB2-associated binding protein 2
GPATCH2L G patch domain containing 2-like
GUSBP3 glucuronidase, beta pseudogene 3
HDAC3 histone deacetylase 3
IL17RB interleukin 17 receptor B
INSIG2 insulin induced gene 2
ISL1 ISL LIM homeobox 1
KIAA1549L KIAA1549-like
KIFC1 kinesin family member C1
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MANEA mannosidase, endo-alpha
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MCM9 minichromosome maintenance complex component 9
MCTP2 multiple C2 domains, transmembrane 2
MEX3C mex-3 RNA binding family member C
MICALL2 MICAL-like 2
MMP1 matrix metallopeptidase 1
MMRN2 multimerin 2
MOXD1 monooxygenase, DBH-like 1
MSL2 male-specific lethal 2 homolog (Drosophila)
NARFL nuclear prelamin A recognition factor-like
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAIP2B poly(A) binding protein interacting protein 2B
PCBP4 poly(rC) binding protein 4
PDGFRL platelet-derived growth factor receptor-like
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIBF1 progesterone immunomodulatory binding factor 1
PLAC1 placenta-specific 1
PLCD1 phospholipase C, delta 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTGFR prostaglandin F receptor (FP)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCARD PYD and CARD domain containing
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL6 RAB, member RAS oncogene family-like 6
RARS arginyl-tRNA synthetase
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCIN scinderin
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC16A6 solute carrier family 16, member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM104 transmembrane protein 104
TMEM159 transmembrane protein 159
TMEM183A transmembrane protein 183A
TRIM25 tripartite motif containing 25
TSPAN12 tetraspanin 12
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
USP32 ubiquitin specific peptidase 32
WDR47 WD repeat domain 47
WDR62 WD repeat domain 62
WDR91 WD repeat domain 91
WWC2 WW and C2 domain containing 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZDHHC13 zinc finger, DHHC-type containing 13
ZMYM3 zinc finger, MYM-type 3
ZNF107 zinc finger protein 107
ZNF573 zinc finger protein 573