meteneprost-7552 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the meteneprost-7552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
ANAPC5 anaphase promoting complex subunit 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD12 ankyrin repeat domain 12
ATRN attractin
ATXN1 ataxin 1
BAX BCL2-associated X protein
BLMH bleomycin hydrolase
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C2ORF68 chromosome 2 open reading frame 68
C5 complement component 5
CASP8AP2 caspase 8 associated protein 2
CBR4 carbonyl reductase 4
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHMP7 charged multivesicular body protein 7
COL18A1 collagen, type XVIII, alpha 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ENDOD1 endonuclease domain containing 1
ERLIN1 ER lipid raft associated 1
FAM188A family with sequence similarity 188, member A
FZD5 frizzled class receptor 5
GCDH glutaryl-CoA dehydrogenase
GNB5 guanine nucleotide binding protein (G protein), beta 5
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGFBP5 insulin-like growth factor binding protein 5
ITSN1 intersectin 1 (SH3 domain protein)
JADE2 jade family PHD finger 2
KDM4B lysine (K)-specific demethylase 4B
KIAA0485 uncharacterized LOC57235
KIDINS220 kinase D-interacting substrate, 220kDa
KIF5C kinesin family member 5C
KLHL26 kelch-like family member 26
LPIN1 lipin 1
LRRC1 leucine rich repeat containing 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAPK1 mitogen-activated protein kinase 1
MAST3 microtubule associated serine/threonine kinase 3
MDC1 mediator of DNA-damage checkpoint 1
MED14 mediator complex subunit 14
METTL3 methyltransferase like 3
METTL4 methyltransferase like 4
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NNT nicotinamide nucleotide transhydrogenase
PER2 period circadian clock 2
PEX13 peroxisomal biogenesis factor 13
PINK1 PTEN induced putative kinase 1
PLXND1 plexin D1
POMT2 protein-O-mannosyltransferase 2
PTEN phosphatase and tensin homolog
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PUM1 pumilio RNA-binding family member 1
QDPR quinoid dihydropteridine reductase
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB27B RAB27B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RIBC2 RIB43A domain with coiled-coils 2
RING1 ring finger protein 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
S100A4 S100 calcium binding protein A4
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD4 SET domain containing 4
SH2D4A SH2 domain containing 4A
SIN3B SIN3 transcription regulator family member B
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SMC2 structural maintenance of chromosomes 2
SPAST spastin
SS18 synovial sarcoma translocation, chromosome 18
ST20 suppressor of tumorigenicity 20
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TET3 tet methylcytosine dioxygenase 3
TGIF2 TGFB-induced factor homeobox 2
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRAPPC10 trafficking protein particle complex 10
TRIM27 tripartite motif containing 27
TUBGCP5 tubulin, gamma complex associated protein 5
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2L3 ubiquitin-conjugating enzyme E2L 3
URGCP upregulator of cell proliferation
USP20 ubiquitin specific peptidase 20
VEGFA vascular endothelial growth factor A
WRN Werner syndrome, RecQ helicase-like
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZMYM1 zinc finger, MYM-type 1
ZNF14 zinc finger protein 14
ZNF282 zinc finger protein 282
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AEBP1 AE binding protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
ARMC6 armadillo repeat containing 6
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C2ORF44 chromosome 2 open reading frame 44
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC64 coiled-coil domain containing 64
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTRL chymotrypsin-like
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DNAL4 dynein, axonemal, light chain 4
ERC2-IT1 ERC2 intronic transcript 1
FIP1L1 factor interacting with PAPOLA and CPSF1
FLJ22184
FMOD fibromodulin
GEM GTP binding protein overexpressed in skeletal muscle
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR182 G protein-coupled receptor 182
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AI histone cluster 1, H2ai
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRX4 iroquois homeobox 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JAM2 junctional adhesion molecule 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL25 kelch-like family member 25
KPTN kaptin (actin binding protein)
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
MEP1B meprin A, beta
MMP13 matrix metallopeptidase 13
MUC2 mucin 2, oligomeric mucus/gel-forming
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NLRX1 NLR family member X1
NRSN2 neurensin 2
NXPH3 neurexophilin 3
OPHN1 oligophrenin 1
PADI1 peptidyl arginine deiminase, type I
PAX1 paired box 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODNL1 podocan-like 1
RAB32 RAB32, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL1 retinoblastoma-like 1
RFTN1 raftlin, lipid raft linker 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIC8B RIC8 guanine nucleotide exchange factor B
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RORC RAR-related orphan receptor C
RPL13P5 ribosomal protein L13 pseudogene 5
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SLC12A9 solute carrier family 12, member 9
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC26A10 solute carrier family 26, member 10
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SP4 Sp4 transcription factor
STIM1 stromal interaction molecule 1
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN transgelin
TAS2R4 taste receptor, type 2, member 4
TBL3 transducin (beta)-like 3
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC22D4 TSC22 domain family, member 4
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VASP vasodilator-stimulated phosphoprotein
VPS9D1 VPS9 domain containing 1
WLS wntless Wnt ligand secretion mediator
WNT16 wingless-type MMTV integration site family, member 16
XAF1 XIAP associated factor 1
ZNF205 zinc finger protein 205
ZNF571 zinc finger protein 571
ZNF862 zinc finger protein 862