meteneprost-7500 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the meteneprost-7500 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHCYL2 adenosylhomocysteinase-like 2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASB1 ankyrin repeat and SOCS box containing 1
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC28B coiled-coil domain containing 28B
CDK18 cyclin-dependent kinase 18
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CLMN calmin (calponin-like, transmembrane)
COL1A1 collagen, type I, alpha 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DGCR8 DGCR8 microprocessor complex subunit
DUSP4 dual specificity phosphatase 4
EFNB3 ephrin-B3
EIF5 eukaryotic translation initiation factor 5
EPHA2 EPH receptor A2
FBXO31 F-box protein 31
FEM1B fem-1 homolog b (C. elegans)
GH1 growth hormone 1
GLS glutaminase
GPC1 glypican 1
GSTT1 glutathione S-transferase theta 1
HDAC7 histone deacetylase 7
HIST1H2AL histone cluster 1, H2al
HIST1H2BJ histone cluster 1, H2bj
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ISG20 interferon stimulated exonuclease gene 20kDa
JADE2 jade family PHD finger 2
JUN jun proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF7 Kruppel-like factor 7 (ubiquitous)
KREMEN2 kringle containing transmembrane protein 2
LAMP1 lysosomal-associated membrane protein 1
LIG3 ligase III, DNA, ATP-dependent
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCOLN1 mucolipin 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MVK mevalonate kinase
MXD4 MAX dimerization protein 4
NCAPH2 non-SMC condensin II complex, subunit H2
NEK1 NIMA-related kinase 1
NPFFR1 neuropeptide FF receptor 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCBP4 poly(rC) binding protein 4
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PDCD1 programmed cell death 1
POFUT1 protein O-fucosyltransferase 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PSEN2 presenilin 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RABGAP1 RAB GTPase activating protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM19 RNA binding motif protein 19
RRAGD Ras-related GTP binding D
RUFY3 RUN and FYVE domain containing 3
SH2D4A SH2 domain containing 4A
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOD2 superoxide dismutase 2, mitochondrial
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF11 serine/arginine-rich splicing factor 11
STX3 syntaxin 3
SYBU syntabulin (syntaxin-interacting)
SYNGR1 synaptogyrin 1
TADA3 transcriptional adaptor 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGIF2 TGFB-induced factor homeobox 2
TJAP1 tight junction associated protein 1 (peripheral)
TMEM209 transmembrane protein 209
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIO trio Rho guanine nucleotide exchange factor
TSC2 tuberous sclerosis 2
TSC22D4 TSC22 domain family, member 4
TTLL5 tubulin tyrosine ligase-like family member 5
U2AF2 U2 small nuclear RNA auxiliary factor 2
URI1 URI1, prefoldin-like chaperone
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFC vascular endothelial growth factor C
WDR76 WD repeat domain 76
ZER1 zyg-11 related, cell cycle regulator
ZNF444 zinc finger protein 444
ZNF609 zinc finger protein 609
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ADAM15 ADAM metallopeptidase domain 15
AIDA axin interactor, dorsalization associated
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ATAT1 alpha tubulin acetyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF21 chromosome 11 open reading frame 21
C22ORF46 chromosome 22 open reading frame 46
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CHMP6 charged multivesicular body protein 6
CRYBG3 beta-gamma crystallin domain containing 3
CTRL chymotrypsin-like
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
EGFL7 EGF-like-domain, multiple 7
EIF5A2 eukaryotic translation initiation factor 5A2
FAM212B family with sequence similarity 212, member B
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF23 fibroblast growth factor 23
FLNC filamin C, gamma
FRMD1 FERM domain containing 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLB1L galactosidase, beta 1-like
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HCRTR2 hypocretin (orexin) receptor 2
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IL36RN interleukin 36 receptor antagonist
INPP1 inositol polyphosphate-1-phosphatase
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIF18A kinesin family member 18A
KRT83 keratin 83, type II
LINC00597 long intergenic non-protein coding RNA 597
LNPEP leucyl/cystinyl aminopeptidase
LOC642236 FSHD region gene 1 pseudogene
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAK male germ cell-associated kinase
MAL mal, T-cell differentiation protein
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP9 microtubule-associated protein 9
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEK11 NIMA-related kinase 11
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDHB12 protocadherin beta 12
PCDHGB5 protocadherin gamma subfamily B, 5
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
R3HCC1L R3H domain and coiled-coil containing 1-like
RABL3 RAB, member of RAS oncogene family-like 3
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFX7 regulatory factor X, 7
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RPL23AP32 ribosomal protein L23a pseudogene 32
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSGA10 testis specific, 10
TUBA3D tubulin, alpha 3d
TUBA4B tubulin, alpha 4b
TUBA8 tubulin, alpha 8
UPK3A uroplakin 3A
YIPF5 Yip1 domain family, member 5
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF573 zinc finger protein 573
ZNF654 zinc finger protein 654