metaraminol-7368 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the metaraminol-7368 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEN apoptosis enhancing nuclease
ANXA10 annexin A10
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARL14 ADP-ribosylation factor-like 14
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDHR2 cadherin-related family member 2
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP162 centrosomal protein 162kDa
CIDEC cell death-inducing DFFA-like effector c
CLTA clathrin, light chain A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CPNE7 copine VII
CRTC1 CREB regulated transcription coactivator 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTH cystathionine gamma-lyase
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DFNB31 deafness, autosomal recessive 31
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DMBT1 deleted in malignant brain tumors 1
DTX3 deltex 3, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
ELL elongation factor RNA polymerase II
EPAS1 endothelial PAS domain protein 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FRS2 fibroblast growth factor receptor substrate 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPER1 G protein-coupled estrogen receptor 1
GPR6 G protein-coupled receptor 6
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUK1 guanylate kinase 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
IFNA14 interferon, alpha 14
IGL immunoglobulin lambda locus
IL11 interleukin 11
IL6 interleukin 6
INADL InaD-like (Drosophila)
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0485 uncharacterized LOC57235
KIAA1644 KIAA1644
KRT24 keratin 24, type I
LIM2 lens intrinsic membrane protein 2, 19kDa
LIMK2 LIM domain kinase 2
LINC00472 long intergenic non-protein coding RNA 472
LMF2 lipase maturation factor 2
LMNA lamin A/C
LYPD3 LY6/PLAUR domain containing 3
MADD MAP-kinase activating death domain
MAP7 microtubule-associated protein 7
MFAP2 microfibrillar-associated protein 2
MFAP3 microfibrillar-associated protein 3
MLX MLX, MAX dimerization protein
MR1 major histocompatibility complex, class I-related
MRC2 mannose receptor, C type 2
NDP Norrie disease (pseudoglioma)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PASK PAS domain containing serine/threonine kinase
PDE11A phosphodiesterase 11A
PDE8B phosphodiesterase 8B
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM4 PDZ and LIM domain 4
PDZD7 PDZ domain containing 7
PER1 period circadian clock 1
PER2 period circadian clock 2
PLXND1 plexin D1
PML promyelocytic leukemia
POU5F1B POU class 5 homeobox 1B
PPAP2B phosphatidic acid phosphatase type 2B
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
RAB31 RAB31, member RAS oncogene family
SARM1 sterile alpha and TIR motif containing 1
SCD5 stearoyl-CoA desaturase 5
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SPRR1A small proline-rich protein 1A
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STC1 stanniocalcin 1
TAGLN3 transgelin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TESK2 testis-specific kinase 2
TF transferrin
TFEB transcription factor EB
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM242 transmembrane protein 242
TNPO2 transportin 2
TRIM29 tripartite motif containing 29
WSB1 WD repeat and SOCS box containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZER1 zyg-11 related, cell cycle regulator
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ADRB2 adrenoceptor beta 2, surface
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALS2CL ALS2 C-terminal like
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD36 ankyrin repeat domain 36
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BAG4 BCL2-associated athanogene 4
BIRC3 baculoviral IAP repeat containing 3
C1ORF115 chromosome 1 open reading frame 115
C1ORF159 chromosome 1 open reading frame 159
C3ORF52 chromosome 3 open reading frame 52
CBX4 chromobox homolog 4
CCS copper chaperone for superoxide dismutase
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK9 cyclin-dependent kinase 9
CLDN14 claudin 14
CLDN4 claudin 4
CPA4 carboxypeptidase A4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTPS2 CTP synthase 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYB5R4 cytochrome b5 reductase 4
DUSP5 dual specificity phosphatase 5
EAF2 ELL associated factor 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FCHO1 FCH domain only 1
FOXC1 forkhead box C1
FOXJ2 forkhead box J2
FYCO1 FYVE and coiled-coil domain containing 1
GMIP GEM interacting protein
GPALPP1 GPALPP motifs containing 1
GRAMD3 GRAM domain containing 3
GRWD1 glutamate-rich WD repeat containing 1
GYS1 glycogen synthase 1 (muscle)
HOMER2 homer scaffolding protein 2
HOXC8 homeobox C8
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL15RA interleukin 15 receptor, alpha
IMPACT impact RWD domain protein
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0513 KIAA0513
KIF16B kinesin family member 16B
KRT15 keratin 15, type I
LIG4 ligase IV, DNA, ATP-dependent
LINS lines homolog (Drosophila)
LPAR6 lysophosphatidic acid receptor 6
MAGEF1 melanoma antigen family F1
MEIS1 Meis homeobox 1
MFSD10 major facilitator superfamily domain containing 10
MMP1 matrix metallopeptidase 1
MOAP1 modulator of apoptosis 1
MOCS3 molybdenum cofactor synthesis 3
MT1M metallothionein 1M
MYO1D myosin ID
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NBEAL2 neurobeachin-like 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NR3C2 nuclear receptor subfamily 3, group C, member 2
P3H1 prolyl 3-hydroxylase 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAQR4 progestin and adipoQ receptor family member IV
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPT2 palmitoyl-protein thioesterase 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB33B RAB33B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RANBP17 RAN binding protein 17
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS17 regulator of G-protein signaling 17
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RUNX1-IT1 RUNX1 intronic transcript 1
SIRT2 sirtuin 2
SNTA1 syntrophin, alpha 1
SORBS3 sorbin and SH3 domain containing 3
SSNA1 Sjogren syndrome nuclear autoantigen 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR2 toll-like receptor 2
TMC7 transmembrane channel-like 7
TMEM132A transmembrane protein 132A
TMEM2 transmembrane protein 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPK1 thiamin pyrophosphokinase 1
TRABD TraB domain containing
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
ZDHHC24 zinc finger, DHHC-type containing 24
ZMAT5 zinc finger, matrin-type 5
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF551 zinc finger protein 551
ZNF668 zinc finger protein 668
ZNF84 zinc finger protein 84
ZSCAN31 zinc finger and SCAN domain containing 31