metaraminol-4692 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the metaraminol-4692 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADCK4 aarF domain containing kinase 4
AMPD3 adenosine monophosphate deaminase 3
ANAPC13 anaphase promoting complex subunit 13
ANAPC5 anaphase promoting complex subunit 5
ANGEL2 angel homolog 2 (Drosophila)
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP1 bone morphogenetic protein 1
C2ORF72 chromosome 2 open reading frame 72
CACFD1 calcium channel flower domain containing 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC121 coiled-coil domain containing 121
CCDC68 coiled-coil domain containing 68
CD6 CD6 molecule
CFAP69 cilia and flagella associated protein 69
CNOT4 CCR4-NOT transcription complex, subunit 4
CREM cAMP responsive element modulator
CST6 cystatin E/M
CXCR4 chemokine (C-X-C motif) receptor 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DPF1 D4, zinc and double PHD fingers family 1
DSC2 desmocollin 2
EVA1B eva-1 homolog B (C. elegans)
FFAR2 free fatty acid receptor 2
FSCN1 fascin actin-bundling protein 1
GALC galactosylceramidase
GID4 GID complex subunit 4
GLP1R glucagon-like peptide 1 receptor
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR143 G protein-coupled receptor 143
GTDC1 glycosyltransferase-like domain containing 1
GYG2 glycogenin 2
IL11 interleukin 11
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA1109 KIAA1109
KLF2 Kruppel-like factor 2
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT6B keratin 6B, type II
LAMP1 lysosomal-associated membrane protein 1
LIMK2 LIM domain kinase 2
LTBP4 latent transforming growth factor beta binding protein 4
MAL mal, T-cell differentiation protein
MATN3 matrilin 3
MSMB microseminoprotein, beta-
MTRF1L mitochondrial translational release factor 1-like
NCALD neurocalcin delta
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGDN neuroguidin, EIF4E binding protein
NME5 NME/NM23 family member 5
NOP16 NOP16 nucleolar protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA5 protocadherin alpha 5
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDIA2 protein disulfide isomerase family A, member 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLD2 phospholipase D2
PLVAP plasmalemma vesicle associated protein
PRKD1 protein kinase D1
PSG6 pregnancy specific beta-1-glycoprotein 6
PTBP3 polypyrimidine tract binding protein 3
PTHLH parathyroid hormone-like hormone
QKI QKI, KH domain containing, RNA binding
RAB30 RAB30, member RAS oncogene family
RAI2 retinoic acid induced 2
RB1CC1 RB1-inducible coiled-coil 1
RBBP6 retinoblastoma binding protein 6
RPL10L ribosomal protein L10-like
RUNX3 runt-related transcription factor 3
SAP30 Sin3A-associated protein, 30kDa
SERHL2 serine hydrolase-like 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SRD5A3 steroid 5 alpha-reductase 3
TBX3 T-box 3
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TFF2 trefoil factor 2
TMCO6 transmembrane and coiled-coil domains 6
TMEM194A transmembrane protein 194A
TRIM10 tripartite motif containing 10
TRIM36 tripartite motif containing 36
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YTHDC2 YTH domain containing 2
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
ALPK1 alpha-kinase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CDHR2 cadherin-related family member 2
CENPO centromere protein O
CIR1 corepressor interacting with RBPJ, 1
CLCN6 chloride channel, voltage-sensitive 6
CLIC2 chloride intracellular channel 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CPTP ceramide-1-phosphate transfer protein
CSTA cystatin A (stefin A)
CUZD1 CUB and zona pellucida-like domains 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCAF13 DDB1 and CUL4 associated factor 13
DNALI1 dynein, axonemal, light intermediate chain 1
DRD1 dopamine receptor D1
DSPP dentin sialophosphoprotein
DYSF dysferlin
ERCC4 excision repair cross-complementation group 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC8 homeobox C8
IFT140 intraflagellar transport 140
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM8 lysine (K)-specific demethylase 8
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT31 keratin 31, type I
LAMA3 laminin, alpha 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED18 mediator complex subunit 18
MFSD11 major facilitator superfamily domain containing 11
MYLK myosin light chain kinase
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGP phosphoglycolate phosphatase
PIDD1 p53-induced death domain protein 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POM121 POM121 transmembrane nucleoporin
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAB3A RAB3A, member RAS oncogene family
RCAN3 RCAN family member 3
RIN1 Ras and Rab interactor 1
RNF208 ring finger protein 208
SAA3P serum amyloid A3 pseudogene
SCAI suppressor of cancer cell invasion
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A8 solute carrier family 12, member 8
SNHG3 small nucleolar RNA host gene 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TDRD12 tudor domain containing 12
TMEM212 transmembrane protein 212
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF205 zinc finger protein 205
ZNF428 zinc finger protein 428
ZNF574 zinc finger protein 574
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669