metampicillin-2123 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the metampicillin-2123 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRD12 ankyrin repeat domain 12
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARFRP1 ADP-ribosylation factor related protein 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN7L3B ataxin 7-like 3B
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C11ORF30 chromosome 11 open reading frame 30
CAMKMT calmodulin-lysine N-methyltransferase
CCL20 chemokine (C-C motif) ligand 20
CEP290 centrosomal protein 290kDa
CLPS colipase, pancreatic
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTSZ cathepsin Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DPYSL3 dihydropyrimidinase-like 3
EML2 echinoderm microtubule associated protein like 2
EMP1 epithelial membrane protein 1
EPHA1 EPH receptor A1
F2R coagulation factor II (thrombin) receptor
FAM63B family with sequence similarity 63, member B
FDPS farnesyl diphosphate synthase
FGF1 fibroblast growth factor 1 (acidic)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GPX2 glutathione peroxidase 2
GRAMD4 GRAM domain containing 4
H1F0 H1 histone family, member 0
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
HOXA2 homeobox A2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KHSRP KH-type splicing regulatory protein
KIFC1 kinesin family member C1
KLK10 kallikrein-related peptidase 10
KRIT1 KRIT1, ankyrin repeat containing
LMNB1 lamin B1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAX MYC associated factor X
METTL5 methyltransferase like 5
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MOCS1 molybdenum cofactor synthesis 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
OTUD4 OTU deubiquitinase 4
PAPPA2 pappalysin 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PFDN6 prefoldin subunit 6
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP3 plakophilin 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRPH peripherin
PVR poliovirus receptor
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB35 RAB35, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD23B RAD23 homolog B (S. cerevisiae)
RBM3 RNA binding motif (RNP1, RRM) protein 3
REST RE1-silencing transcription factor
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETD8 SET domain containing (lysine methyltransferase) 8
SF3A1 splicing factor 3a, subunit 1, 120kDa
SIRT6 sirtuin 6
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS6 suppressor of cytokine signaling 6
SOX13 SRY (sex determining region Y)-box 13
SRRM2 serine/arginine repetitive matrix 2
STAT1 signal transducer and activator of transcription 1, 91kDa
SYNE1 spectrin repeat containing, nuclear envelope 1
TFG TRK-fused gene
TGFA transforming growth factor, alpha
THRAP3 thyroid hormone receptor associated protein 3
TM2D1 TM2 domain containing 1
TRIM14 tripartite motif containing 14
TSC22D4 TSC22 domain family, member 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USF2 upstream transcription factor 2, c-fos interacting
XAF1 XIAP associated factor 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZHX3 zinc fingers and homeoboxes 3
ZNF14 zinc finger protein 14

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP2 acylphosphatase 2, muscle type
ALPK1 alpha-kinase 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL14 ADP-ribosylation factor-like 14
BAHD1 bromo adjacent homology domain containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF45 chromosome 16 open reading frame 45
C16ORF62 chromosome 16 open reading frame 62
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF3 chromosome 9 open reading frame 3
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMTA2 calmodulin binding transcription activator 2
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CIDEC cell death-inducing DFFA-like effector c
CLEC2B C-type lectin domain family 2, member B
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CORO2A coronin, actin binding protein, 2A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CUEDC1 CUE domain containing 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DMBT1 deleted in malignant brain tumors 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP8 dual specificity phosphatase 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA4 ephrin-A4
EN1 engrailed homeobox 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FBXL7 F-box and leucine-rich repeat protein 7
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXC1 forkhead box C1
FURIN furin (paired basic amino acid cleaving enzyme)
GPR1 G protein-coupled receptor 1
GPR4 G protein-coupled receptor 4
HMHA1 histocompatibility (minor) HA-1
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA10 integrin, alpha 10
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
LOC100272216 uncharacterized LOC100272216
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
MED15 mediator complex subunit 15
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MVP major vault protein
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PDGFD platelet derived growth factor D
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRR7 proline rich 7 (synaptic)
PRSS53 protease, serine, 53
RABL6 RAB, member RAS oncogene family-like 6
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUFY2 RUN and FYVE domain containing 2
RUSC2 RUN and SH3 domain containing 2
S1PR1 sphingosine-1-phosphate receptor 1
SETD6 SET domain containing 6
SH3BGR SH3 domain binding glutamate-rich protein
SLC35F6 solute carrier family 35, member F6
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNPH syntaphilin
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TBC1D19 TBC1 domain family, member 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM159 transmembrane protein 159
TMEM53 transmembrane protein 53
TPCN1 two pore segment channel 1
TPK1 thiamin pyrophosphokinase 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBQLN4 ubiquilin 4
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WNT7A wingless-type MMTV integration site family, member 7A
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF134 zinc finger protein 134
ZNF137P zinc finger protein 137, pseudogene
ZNF141 zinc finger protein 141
ZNF180 zinc finger protein 180
ZNF205 zinc finger protein 205
ZNF264 zinc finger protein 264
ZNF350 zinc finger protein 350
ZNF862 zinc finger protein 862