metamizole sodium-3835 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the metamizole sodium-3835 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALX4 ALX homeobox 4
ANXA2P1 annexin A2 pseudogene 1
ARHGAP4 Rho GTPase activating protein 4
ASIC1 acid sensing (proton gated) ion channel 1
ATAD5 ATPase family, AAA domain containing 5
ATG10 autophagy related 10
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BANK1 B-cell scaffold protein with ankyrin repeats 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1ORF61 chromosome 1 open reading frame 61
C1QL1 complement component 1, q subcomponent-like 1
C2ORF27A chromosome 2 open reading frame 27A
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASC1 cancer susceptibility candidate 1
CASQ2 calsequestrin 2 (cardiac muscle)
CCR4 chemokine (C-C motif) receptor 4
CD1A CD1a molecule
CD2 CD2 molecule
CD84 CD84 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH18 cadherin 18, type 2
COL17A1 collagen, type XVII, alpha 1
COL1A1 collagen, type I, alpha 1
CPNE7 copine VII
CRHR2 corticotropin releasing hormone receptor 2
CRIP1 cysteine-rich protein 1 (intestinal)
CYLD cylindromatosis (turban tumor syndrome)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DENND5B DENN/MADD domain containing 5B
DHRS12 dehydrogenase/reductase (SDR family) member 12
DIXDC1 DIX domain containing 1
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTNB dystrobrevin, beta
ECM1 extracellular matrix protein 1
EGFR epidermal growth factor receptor
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELOVL5 ELOVL fatty acid elongase 5
EN2 engrailed homeobox 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FST follistatin
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
HMHB1 histocompatibility (minor) HB-1
ICA1 islet cell autoantigen 1, 69kDa
IFT27 intraflagellar transport 27
ITPKA inositol-trisphosphate 3-kinase A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF6 Kruppel-like factor 6
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LPAR1 lysophosphatidic acid receptor 1
LRP2 low density lipoprotein receptor-related protein 2
MAP1A microtubule-associated protein 1A
MOB3B MOB kinase activator 3B
MTSS1L metastasis suppressor 1-like
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NR4A3 nuclear receptor subfamily 4, group A, member 3
PAIP2B poly(A) binding protein interacting protein 2B
PARVA parvin, alpha
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDGFA platelet-derived growth factor alpha polypeptide
PEX16 peroxisomal biogenesis factor 16
PHF20L1 PHD finger protein 20-like 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLK3 polo-like kinase 3
PLXNB3 plexin B3
PSD4 pleckstrin and Sec7 domain containing 4
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RIF1 replication timing regulatory factor 1
RPA4 replication protein A4, 30kDa
RPGR retinitis pigmentosa GTPase regulator
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SELL selectin L
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3D21 SH3 domain containing 21
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SOX10 SRY (sex determining region Y)-box 10
SP1 Sp1 transcription factor
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBX3 T-box 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TDRD12 tudor domain containing 12
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
ZKSCAN3 zinc finger with KRAB and SCAN domains 3

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACSF2 acyl-CoA synthetase family member 2
ADM adrenomedullin
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARMC6 armadillo repeat containing 6
ARR3 arrestin 3, retinal (X-arrestin)
ASIC3 acid sensing (proton gated) ion channel 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCAS1 breast carcinoma amplified sequence 1
C10ORF95 chromosome 10 open reading frame 95
C8ORF60 chromosome 8 open reading frame 60
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
DEXI Dexi homolog (mouse)
DGKE diacylglycerol kinase, epsilon 64kDa
DNAH17 dynein, axonemal, heavy chain 17
DUSP13 dual specificity phosphatase 13
EMID1 EMI domain containing 1
EPHB6 EPH receptor B6
EPHX2 epoxide hydrolase 2, cytoplasmic
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FBXL8 F-box and leucine-rich repeat protein 8
FFAR2 free fatty acid receptor 2
FILIP1L filamin A interacting protein 1-like
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
GPR21 G protein-coupled receptor 21
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTA4 glutathione S-transferase alpha 4
GTF2I general transcription factor IIi
HDAC11 histone deacetylase 11
HIST1H1B histone cluster 1, H1b
HIST1H4E histone cluster 1, H4e
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXB2 homeobox B2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFNA14 interferon, alpha 14
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO8 importin 8
JMJD4 jumonji domain containing 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIFC1 kinesin family member C1
KLHL28 kelch-like family member 28
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MGC12488
MUC3A mucin 3A, cell surface associated
NPM3 nucleophosmin/nucleoplasmin 3
NPPA natriuretic peptide A
OVOL1 ovo-like zinc finger 1
PCDHGB5 protocadherin gamma subfamily B, 5
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RASA2 RAS p21 protein activator 2
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
SCRN3 secernin 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPON2 spondin 2, extracellular matrix protein
STARD3 StAR-related lipid transfer (START) domain containing 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TMEM120B transmembrane protein 120B
TNS2 tensin 2
TONSL tonsoku-like, DNA repair protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
USP19 ubiquitin specific peptidase 19
VIPR1 vasoactive intestinal peptide receptor 1
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
YEATS2 YEATS domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZMAT4 zinc finger, matrin-type 4
ZNF136 zinc finger protein 136
ZNF250 zinc finger protein 250
ZNF41 zinc finger protein 41
ZNF480 zinc finger protein 480
ZNF484 zinc finger protein 484
ZNF862 zinc finger protein 862
ZSCAN2 zinc finger and SCAN domain containing 2