metal metabolism disorder Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An inherited metabolic disorder that involves metabolic disturbances in the processing or distribution of dietary minerals. (Human Disease Ontology, DOID_896)
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Genes

522 genes co-occuring with the disease metal metabolism disorder in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HFE hemochromatosis 3.97247
ATP7A ATPase, Cu++ transporting, alpha polypeptide 3.1499
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.98467
TF transferrin 2.75744
HAMP hepcidin antimicrobial peptide 2.66802
CP ceruloplasmin (ferroxidase) 2.6599
TFR2 transferrin receptor 2 2.59677
PHEX phosphate regulating endopeptidase homolog, X-linked 2.51304
HFE2 hemochromatosis type 2 (juvenile) 2.50606
FTL ferritin, light polypeptide 2.4779
FTH1 ferritin, heavy polypeptide 1 2.46686
GNAS GNAS complex locus 2.34272
PTH parathyroid hormone 2.21324
FGF23 fibroblast growth factor 23 2.2095
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.09618
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.03651
DNAH8 dynein, axonemal, heavy chain 8 1.99039
TFRC transferrin receptor 1.9769
ATOX1 antioxidant 1 copper chaperone 1.9066
SLC39A4 solute carrier family 39 (zinc transporter), member 4 1.83727
STX16 syntaxin 16 1.81194
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.81104
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 1.75187
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.71499
MEPE matrix extracellular phosphoglycoprotein 1.69405
COMMD1 copper metabolism (Murr1) domain containing 1 1.46363
HEPH hephaestin 1.46363
CASR calcium-sensing receptor 1.44298
CYBRD1 cytochrome b reductase 1 1.41271
TMPRSS6 transmembrane protease, serine 6 1.38909
UROD uroporphyrinogen decarboxylase 1.38516
HLA-F major histocompatibility complex, class I, F 1.38254
HCG4P11 HLA complex group 4 pseudogene 11 1.38254
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 1.31843
HLA-A major histocompatibility complex, class I, A 1.31624
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.31537
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.28479
ALPPL2 alkaline phosphatase, placental-like 2 1.27824
ALPP alkaline phosphatase, placental 1.27737
ALPL alkaline phosphatase, liver/bone/kidney 1.27693
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.26124
EMP1 epithelial membrane protein 1 1.22735
DMP1 dentin matrix acidic phosphoprotein 1 1.18626
UBE2D1 ubiquitin-conjugating enzyme E2D 1 1.16863
BMP6 bone morphogenetic protein 6 1.15112
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.1456
KL klotho 1.07572
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.06396
SLITRK1 SLIT and NTRK-like family, member 1 1.05681
SLC30A4 solute carrier family 30 (zinc transporter), member 4 1.05639
HLA-B major histocompatibility complex, class I, B 1.04714
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.0383
FAM20C family with sequence similarity 20, member C 1.03409
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 1.02271
ADCY2 adenylate cyclase 2 (brain) 0.988535
B2M beta-2-microglobulin 0.948269
ALB albumin 0.926692
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.899103
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.881472
ESD esterase D 0.878195
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.871234
INS insulin 0.84585
F2 coagulation factor II (thrombin) 0.822488
PANK1 pantothenate kinase 1 0.794181
CLCN5 chloride channel, voltage-sensitive 5 0.763494
HMGN4 high mobility group nucleosomal binding domain 4 0.750864
SOD2 superoxide dismutase 2, mitochondrial 0.739894
FGF1 fibroblast growth factor 1 (acidic) 0.739894
COX17 COX17 cytochrome c oxidase copper chaperone 0.738676
ATP11A ATPase, class VI, type 11A 0.735027
COPB1 coatomer protein complex, subunit beta 1 0.732596
HLA-C major histocompatibility complex, class I, C 0.691094
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.666358
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.665563
GGT1 gamma-glutamyltransferase 1 0.649323
TRH thyrotropin-releasing hormone 0.645375
SKA1 spindle and kinetochore associated complex subunit 1 0.641039
PKLR pyruvate kinase, liver and RBC 0.639857
AFP alpha-fetoprotein 0.637102
BGLAP bone gamma-carboxyglutamate (gla) protein 0.637102
SEC23B Sec23 homolog B (S. cerevisiae) 0.62885
LOX lysyl oxidase 0.624535
CCS copper chaperone for superoxide dismutase 0.617094
HPR haptoglobin-related protein 0.613574
ACO1 aconitase 1, soluble 0.612792
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.59952
GHRH growth hormone releasing hormone 0.595233
CLCN1 chloride channel, voltage-sensitive 1 0.590169
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 0.578106
SLC39A5 solute carrier family 39 (zinc transporter), member 5 0.578106
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.576161
RGMB repulsive guidance molecule family member b 0.566054
HP haptoglobin 0.558674
NEO1 neogenin 1 0.545868
CALCA calcitonin-related polypeptide alpha 0.542767
ATP13A1 ATPase type 13A1 0.541992
ZSCAN9 zinc finger and SCAN domain containing 9 0.541992
RGMA repulsive guidance molecule family member a 0.541992
MFSD6 major facilitator superfamily domain containing 6 0.537731
C2ORF88 chromosome 2 open reading frame 88 0.537731
TMEM194B transmembrane protein 194B 0.537731
ASNSD1 asparagine synthetase domain containing 1 0.537731
ANKAR ankyrin and armadillo repeat containing 0.537731
WDR75 WD repeat domain 75 0.537731
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 0.537731
SFRP4 secreted frizzled-related protein 4 0.535796
SCN3A sodium channel, voltage gated, type III alpha subunit 0.535796
CAPRIN2 caprin family member 2 0.535022
F5 coagulation factor V (proaccelerin, labile factor) 0.533861
HPX hemopexin 0.516494
PTHLH parathyroid hormone-like hormone 0.50689
PKM pyruvate kinase, muscle 0.502675
HIST1H1T histone cluster 1, H1t 0.499997
GGT2 gamma-glutamyltransferase 2 0.499614
GCH1 GTP cyclohydrolase 1 0.492359
PTPRB protein tyrosine phosphatase, receptor type, B 0.481325
ALAD aminolevulinate dehydratase 0.480945
C14ORF177 chromosome 14 open reading frame 177 0.475255
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.47374
COX19 COX19 cytochrome c oxidase assembly factor 0.473361
CD80 CD80 molecule 0.467306
DIRC1 disrupted in renal carcinoma 1 0.466928
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.462016
MGAM maltase-glucoamylase 0.460129
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.458619
HMOX2 heme oxygenase 2 0.456355
MME membrane metallo-endopeptidase 0.455224
PAM peptidylglycine alpha-amidating monooxygenase 0.45447
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.454093
MED4 mediator complex subunit 4 0.449194
MED9 mediator complex subunit 9 0.447687
FURIN furin (paired basic amino acid cleaving enzyme) 0.447687
C11ORF31 chromosome 11 open reading frame 31 0.44129
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.434148
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.429642
HLA-E major histocompatibility complex, class I, E 0.42364
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.421765
ALAS2 5'-aminolevulinate synthase 2 0.420641
ASL argininosuccinate lyase 0.416521
IBSP integrin-binding sialoprotein 0.412031
FXN frataxin 0.410909
MED1 mediator complex subunit 1 0.410161
GCG glucagon 0.407172
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 0.403438
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0.403438
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 0.40008
BMP2 bone morphogenetic protein 2 0.394863
TEX14 testis expressed 14 0.393746
ARSA arylsulfatase A 0.393001
USF2 upstream transcription factor 2, c-fos interacting 0.381481
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.366301
PARD6G par-6 family cell polarity regulator gamma 0.360764
WDR20 WD repeat domain 20 0.359289
FRZB frizzled-related protein 0.354131
COPZ1 coatomer protein complex, subunit zeta 1 0.350452
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.348246
RNASEH2A ribonuclease H2, subunit A 0.341639
GLRA2 glycine receptor, alpha 2 0.341272
PRKG1 protein kinase, cGMP-dependent, type I 0.339806
AANAT aralkylamine N-acetyltransferase 0.339073
SFXN1 sideroflexin 1 0.332852
CAT catalase 0.325552
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.32373
DSPP dentin sialophosphoprotein 0.322637
PANK2 pantothenate kinase 2 0.321181
DCTN4 dynactin 4 (p62) 0.317545
GDF15 growth differentiation factor 15 0.314278
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.312827
SMAD9 SMAD family member 9 0.312464
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.311014
MBD4 methyl-CpG binding domain protein 4 0.307395
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.30631
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.299812
DGUOK deoxyguanosine kinase 0.297291
STK25 serine/threonine kinase 25 0.297291
SOST sclerostin 0.295132
DRD2 dopamine receptor D2 0.293334
FAM20B family with sequence similarity 20, member B 0.291539
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.289744
SCO1 SCO1 cytochrome c oxidase assembly protein 0.28831
IGF1 insulin-like growth factor 1 (somatomedin C) 0.284728
GPX1 glutathione peroxidase 1 0.283655
TMPO thymopoietin 0.283297
APOE apolipoprotein E 0.282225
SNRPN small nuclear ribonucleoprotein polypeptide N 0.282225
COPA coatomer protein complex, subunit alpha 0.281153
CDAN1 codanin 1 0.280796
UROS uroporphyrinogen III synthase 0.279011
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 0.277227
INPP1 inositol polyphosphate-1-phosphatase 0.275801
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.275089
ANKH ANKH inorganic pyrophosphate transport regulator 0.274732
ETV2 ets variant 2 0.27153
BMPR1A bone morphogenetic protein receptor, type IA 0.270464
GPX5 glutathione peroxidase 5 0.267977
GSTA3 glutathione S-transferase alpha 3 0.267267
GSTA2 glutathione S-transferase alpha 2 0.265849
GPX4 glutathione peroxidase 4 0.26514
GSTA4 glutathione S-transferase alpha 4 0.264785
CHPF chondroitin polymerizing factor 0.264077
SMAD5 SMAD family member 5 0.259477
GSTA1 glutathione S-transferase alpha 1 0.259477
FGF6 fibroblast growth factor 6 0.25877
PNOC prepronociceptin 0.258417
COG7 component of oligomeric golgi complex 7 0.253831
HMOX1 heme oxygenase 1 0.250663
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.240847
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.23945
IP6K1 inositol hexakisphosphate kinase 1 0.238752
SNX27 sorting nexin family member 27 0.234573
TYR tyrosinase 0.23353
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.227642
SFRP1 secreted frizzled-related protein 1 0.227297
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.225229
TTC37 tetratricopeptide repeat domain 37 0.224196
NPC1 Niemann-Pick disease, type C1 0.222136
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.221793
MARS methionyl-tRNA synthetase 0.221793
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.216672
SMS spermine synthase 0.216332
TNF tumor necrosis factor 0.214636
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.209583
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.209248
NFASC neurofascin 0.208245
AMTN amelotin 0.207578
IREB2 iron-responsive element binding protein 2 0.205916
ASMT acetylserotonin O-methyltransferase 0.204593
THOP1 thimet oligopeptidase 1 0.204263
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.203275
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.200982
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.19582
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.194865
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.191097
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.188938
LUZP6 leucine zipper protein 6 0.187719
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 0.186811
CFAP20 cilia and flagella associated protein 20 0.186811
SCARA5 scavenger receptor class A, member 5 0.184128
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.182666
POMC proopiomelanocortin 0.18151
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.180367
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.178126
LYPLA1 lysophospholipase I 0.173832
AHCY adenosylhomocysteinase 0.173571
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.173314
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.172291
HMGN2 high mobility group nucleosomal binding domain 2 0.172038
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.172038
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.171785
CRP C-reactive protein, pentraxin-related 0.171535
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.16933
EPS15 epidermal growth factor receptor pathway substrate 15 0.165874
RPLP2 ribosomal protein, large, P2 0.164359
SPP1 secreted phosphoprotein 1 0.161716
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.161139
IL6 interleukin 6 0.160387
ACTG1 actin gamma 1 0.157602
RYR1 ryanodine receptor 1 (skeletal) 0.142336
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.141143
PDE4D phosphodiesterase 4D, cAMP-specific 0.141004
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 0.140527
SCN1B sodium channel, voltage gated, type I beta subunit 0.140419
HDAC4 histone deacetylase 4 0.13974
GRB10 growth factor receptor-bound protein 10 0.139297
QDPR quinoid dihydropteridine reductase 0.139149
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.138932
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.13843
D2HGDH D-2-hydroxyglutarate dehydrogenase 0.138395
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.137694
GPR35 G protein-coupled receptor 35 0.137397
MC4R melanocortin 4 receptor 0.136382
CST7 cystatin F (leukocystatin) 0.136258
PRLH prolactin releasing hormone 0.135615
MN1 meningioma (disrupted in balanced translocation) 1 0.135204
TRDN triadin 0.134911
LRP4 low density lipoprotein receptor-related protein 4 0.134597
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.134138
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.133015
CYCS cytochrome c, somatic 0.132997
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.132844
SPTA1 spectrin, alpha, erythrocytic 1 0.132754
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.131695
KIF1A kinesin family member 1A 0.131629
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.131335
GPC1 glypican 1 0.130552
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.130235
TWIST2 twist family bHLH transcription factor 2 0.130019
TDO2 tryptophan 2,3-dioxygenase 0.129734
BTNL2 butyrophilin-like 2 0.129734
TBK1 TANK-binding kinase 1 0.129442
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.128811
TK1 thymidine kinase 1, soluble 0.128724
KRT1 keratin 1, type II 0.128698
CSN3 casein kappa 0.128523
TNC tenascin C 0.128263
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.126904
LIPE lipase, hormone-sensitive 0.126774
EN1 engrailed homeobox 1 0.126744
CASQ2 calsequestrin 2 (cardiac muscle) 0.125941
ATP13A2 ATPase type 13A2 0.125878
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.125583
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.125184
TSHR thyroid stimulating hormone receptor 0.124878
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.124458
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.123737
CCDC130 coiled-coil domain containing 130 0.123286
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.123274
FECH ferrochelatase 0.123031
ASS1 argininosuccinate synthase 1 0.122136
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.121713
ERCC8 excision repair cross-complementation group 8 0.121533
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.119985
SCO2 SCO2 cytochrome c oxidase assembly protein 0.119664
AVPR2 arginine vasopressin receptor 2 0.119542
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.118981
PGK1 phosphoglycerate kinase 1 0.118854
THRB thyroid hormone receptor, beta 0.118618
DMPK dystrophia myotonica-protein kinase 0.118487
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.118406
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.118308
LCT lactase 0.117982
COX11 COX11 cytochrome c oxidase copper chaperone 0.117295
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.117076
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.115826
BLMH bleomycin hydrolase 0.115374
TGOLN2 trans-golgi network protein 2 0.115263
KIN Kin17 DNA and RNA binding protein 0.114576
GJB1 gap junction protein, beta 1, 32kDa 0.114347
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.114271
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.113984
TREH trehalase (brush-border membrane glycoprotein) 0.112645
IP6K2 inositol hexakisphosphate kinase 2 0.111308
REN renin 0.111225
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.110349
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.109208
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.108643
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.108575
MID1 midline 1 0.108257
TMPRSS15 transmembrane protease, serine 15 0.108189
FGF7 fibroblast growth factor 7 0.107679
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.107679
ZFP57 ZFP57 zinc finger protein 0.107399
PHKG2 phosphorylase kinase, gamma 2 (testis) 0.107003
INHBB inhibin, beta B 0.105185
ORAOV1 oral cancer overexpressed 1 0.105161
FAM20A family with sequence similarity 20, member A 0.104964
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.104186
WRB tryptophan rich basic protein 0.103933
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.103268
FGF14 fibroblast growth factor 14 0.103268
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.102853
NT5E 5'-nucleotidase, ecto (CD73) 0.101723
STC1 stanniocalcin 1 0.101378
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.100974
SC5D sterol-C5-desaturase 0.100892
ANXA7 annexin A7 0.100838
SUCLG1 succinate-CoA ligase, alpha subunit 0.100648
SUOX sulfite oxidase 0.100648
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.100594
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.100594
BTD biotinidase 0.100431
SERAC1 serine active site containing 1 0.100133
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.100106
BPGM 2,3-bisphosphoglycerate mutase 0.100051
KLB klotho beta 0.099996
PGAM2 phosphoglycerate mutase 2 (muscle) 0.099857
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.099718
EDARADD EDAR-associated death domain 0.09969
KRT10 keratin 10, type I 0.099329
NLRP2 NLR family, pyrin domain containing 2 0.099302
IDI1 isopentenyl-diphosphate delta isomerase 1 0.099274
ZMPSTE24 zinc metallopeptidase STE24 0.098941
STC2 stanniocalcin 2 0.098292
OCRL oculocerebrorenal syndrome of Lowe 0.098263
BMP4 bone morphogenetic protein 4 0.097838
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.097583
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.09744
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.097063
ADGRL4 adhesion G protein-coupled receptor L4 0.096454
CIC capicua transcriptional repressor 0.096075
PHB prohibitin 0.095898
CLEC3A C-type lectin domain family 3, member A 0.095809
PGAM1 phosphoglycerate mutase 1 (brain) 0.095513
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.095454
CLEC2B C-type lectin domain family 2, member B 0.095425
OPA1 optic atrophy 1 (autosomal dominant) 0.095425
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.095336
VRK2 vaccinia related kinase 2 0.095277
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.095159
MTF1 metal-regulatory transcription factor 1 0.095041
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.095041
PEX2 peroxisomal biogenesis factor 2 0.094922
ECE2 endothelin converting enzyme 2 0.093959
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.093868
ACTB actin, beta 0.093808
FGFR3 fibroblast growth factor receptor 3 0.093718
VCP valosin containing protein 0.093597
CLEC10A C-type lectin domain family 10, member A 0.093567
LYZ lysozyme 0.093567
TIGAR TP53 induced glycolysis regulatory phosphatase 0.093507
NOBOX NOBOX oogenesis homeobox 0.093384
FABP3 fatty acid binding protein 3, muscle and heart 0.093169
NLRP7 NLR family, pyrin domain containing 7 0.093046
AGXT alanine-glyoxylate aminotransferase 0.093015
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.092954
FGF8 fibroblast growth factor 8 (androgen-induced) 0.092524
PLIN2 perilipin 2 0.092524
PRKD1 protein kinase D1 0.092371
FN3K fructosamine 3 kinase 0.091625
PYCR1 pyrroline-5-carboxylate reductase 1 0.091594
PRL prolactin 0.091281
CCNE1 cyclin E1 0.091156
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.090875
FGF20 fibroblast growth factor 20 0.090242
AMBN ameloblastin (enamel matrix protein) 0.09021
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.089956
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.089924
RNF25 ring finger protein 25 0.089892
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.089447
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 0.089257
CAPN10 calpain 10 0.088836
PDCD1 programmed cell death 1 0.088578
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.088093
GHRHR growth hormone releasing hormone receptor 0.088029
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.087573
PLAGL1 pleiomorphic adenoma gene-like 1 0.087541
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.087442
GCM2 glial cells missing homolog 2 (Drosophila) 0.087212
FGF19 fibroblast growth factor 19 0.086425
ARG2 arginase 2 0.086294
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.085761
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.085329
F13A1 coagulation factor XIII, A1 polypeptide 0.085096
EGR1 early growth response 1 0.085063
JAK3 Janus kinase 3 0.084863
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.08473
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.08473
MT1X metallothionein 1X 0.084662
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.084595
DMD dystrophin 0.084156
TRIP12 thyroid hormone receptor interactor 12 0.084156
GTF2B general transcription factor IIB 0.084122
S100G S100 calcium binding protein G 0.083954
CLCA4 chloride channel accessory 4 0.083718
ZNF202 zinc finger protein 202 0.083616
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.083583
CKAP2 cytoskeleton associated protein 2 0.083549
FBXO2 F-box protein 2 0.083482
NTHL1 nth endonuclease III-like 1 (E. coli) 0.083381
CSN1S1 casein alpha s1 0.083212
SIX6 SIX homeobox 6 0.083177
MPV17 MpV17 mitochondrial inner membrane protein 0.082972
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.08287
CCL8 chemokine (C-C motif) ligand 8 0.082562
G6PD glucose-6-phosphate dehydrogenase 0.082494
COL1A2 collagen, type I, alpha 2 0.082426
MYO5A myosin VA (heavy chain 12, myoxin) 0.082392
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.082221
CAPNS1 calpain, small subunit 1 0.082187
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.081982
PGBD1 piggyBac transposable element derived 1 0.081948
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.081364
HOXC6 homeobox C6 0.081329
WNK1 WNK lysine deficient protein kinase 1 0.081329
TEF thyrotrophic embryonic factor 0.081329
HLA-G major histocompatibility complex, class I, G 0.081295
BMP1 bone morphogenetic protein 1 0.081156
IL2RG interleukin 2 receptor, gamma 0.081122
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.081053
PNPLA3 patatin-like phospholipase domain containing 3 0.08088
ZNF165 zinc finger protein 165 0.080673
CA3 carbonic anhydrase III 0.080638
CREB3L3 cAMP responsive element binding protein 3-like 3 0.080535
BIN2 bridging integrator 2 0.080156
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.080016
CLCA2 chloride channel accessory 2 0.079946
OAT ornithine aminotransferase 0.079806
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.079701
NDP Norrie disease (pseudoglioma) 0.079597
TFF3 trefoil factor 3 (intestinal) 0.079527
FBLN2 fibulin 2 0.079387
GAN gigaxonin 0.079352
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.079108
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.079073
LCAT lecithin-cholesterol acyltransferase 0.078759
FKBP4 FK506 binding protein 4, 59kDa 0.078759
COL10A1 collagen, type X, alpha 1 0.078655
SQLE squalene epoxidase 0.078655
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.07855
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.078409
SOX9 SRY (sex determining region Y)-box 9 0.078338
GLUL glutamate-ammonia ligase 0.078197
NPTX2 neuronal pentraxin II 0.078056
PPOX protoporphyrinogen oxidase 0.07781
VRK1 vaccinia related kinase 1 0.077704
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.077633
PCSK7 proprotein convertase subtilisin/kexin type 7 0.077352
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.077176
NOG noggin 0.077
FGF9 fibroblast growth factor 9 0.076929
GRB7 growth factor receptor-bound protein 7 0.076929
FRS2 fibroblast growth factor receptor substrate 2 0.076822
DDIT4 DNA-damage-inducible transcript 4 0.076716
TCTA T-cell leukemia translocation altered 0.076716
MB myoglobin 0.076644
UNC13D unc-13 homolog D (C. elegans) 0.076609
SEPT4 septin 4 0.075969
CXCR5 chemokine (C-X-C motif) receptor 5 0.075863
SAT1 spermidine/spermine N1-acetyltransferase 1 0.075792
SHOX short stature homeobox 0.075792
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.075756
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.075579
IGF2R insulin-like growth factor 2 receptor 0.075543
ACP2 acid phosphatase 2, lysosomal 0.075508
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.075508
THAP1 THAP domain containing, apoptosis associated protein 1 0.075401
FGF3 fibroblast growth factor 3 0.075401
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.075258
ELANE elastase, neutrophil expressed 0.075079
STEAP3 STEAP family member 3, metalloreductase 0.074936
FBXO7 F-box protein 7 0.074756
CALR calreticulin 0.074721