mestranol-4208 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mestranol-4208 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACVR1B activin A receptor, type IB
AKAP8L A kinase (PRKA) anchor protein 8-like
AQP3 aquaporin 3 (Gill blood group)
B9D1 B9 protein domain 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BIN1 bridging integrator 1
BMP2 bone morphogenetic protein 2
C17ORF70 chromosome 17 open reading frame 70
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDC14A cell division cycle 14A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL9A2 collagen, type IX, alpha 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCR4 chemokine (C-X-C motif) receptor 4
DGCR8 DGCR8 microprocessor complex subunit
DGKA diacylglycerol kinase, alpha 80kDa
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK6 dedicator of cytokinesis 6
DRD2 dopamine receptor D2
DSC2 desmocollin 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGR1 early growth response 1
ELOVL5 ELOVL fatty acid elongase 5
EML2 echinoderm microtubule associated protein like 2
EPHA1 EPH receptor A1
FAM89B family with sequence similarity 89, member B
FBLN1 fibulin 1
FKBP10 FK506 binding protein 10, 65 kDa
FRMD1 FERM domain containing 1
GAMT guanidinoacetate N-methyltransferase
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GON4L gon-4-like (C. elegans)
GPR17 G protein-coupled receptor 17
HAP1 huntingtin-associated protein 1
HOXC11 homeobox C11
HSF2BP heat shock transcription factor 2 binding protein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFI30 interferon, gamma-inducible protein 30
IFITM1 interferon induced transmembrane protein 1
IL22 interleukin 22
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCTD14 potassium channel tetramerization domain containing 14
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA5 melanoma antigen family A5
MAPK11 mitogen-activated protein kinase 11
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP3 matrix metallopeptidase 3
MT1F metallothionein 1F
MT1HL1 metallothionein 1H-like 1
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPEPL1 aminopeptidase-like 1
NPR1 natriuretic peptide receptor 1
NRF1 nuclear respiratory factor 1
OLFM1 olfactomedin 1
OSBPL10 oxysterol binding protein-like 10
PALMD palmdelphin
PAOX polyamine oxidase (exo-N4-amino)
PCDH1 protocadherin 1
PDLIM4 PDZ and LIM domain 4
PDLIM5 PDZ and LIM domain 5
PGPEP1 pyroglutamyl-peptidase I
PI3 peptidase inhibitor 3, skin-derived
POU6F1 POU class 6 homeobox 1
PTHLH parathyroid hormone-like hormone
RAB26 RAB26, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASA3 RAS p21 protein activator 3
RCE1 Ras converting CAAX endopeptidase 1
RPGRIP1L RPGRIP1-like
RPL35A ribosomal protein L35a
SARM1 sterile alpha and TIR motif containing 1
SENP6 SUMO1/sentrin specific peptidase 6
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
STC1 stanniocalcin 1
THRB thyroid hormone receptor, beta
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRA2A transformer 2 alpha homolog (Drosophila)
TRGV5 T cell receptor gamma variable 5
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZBTB20 zinc finger and BTB domain containing 20
ZMAT5 zinc finger, matrin-type 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYM5 zinc finger, MYM-type 5
ZNF3 zinc finger protein 3
ZNF492 zinc finger protein 492
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM2 ADAM metallopeptidase domain 2
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C4 aldo-keto reductase family 1, member C4
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOC4 apolipoprotein C-IV
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BIRC3 baculoviral IAP repeat containing 3
C1ORF21 chromosome 1 open reading frame 21
C3ORF36 chromosome 3 open reading frame 36
C8A complement component 8, alpha polypeptide
CA11 carbonic anhydrase XI
CAMKMT calmodulin-lysine N-methyltransferase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CEMP1 cementum protein 1
CHRDL1 chordin-like 1
CLCN2 chloride channel, voltage-sensitive 2
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CRYGC crystallin, gamma C
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
ERCC4 excision repair cross-complementation group 4
FAM53B family with sequence similarity 53, member B
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HOXB9 homeobox B9
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICOS inducible T-cell co-stimulator
IFNA8 interferon, alpha 8
IFT140 intraflagellar transport 140
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KLF13 Kruppel-like factor 13
KLF3 Kruppel-like factor 3 (basic)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT20 keratin 20, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MAL mal, T-cell differentiation protein
MGP matrix Gla protein
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
MYO15A myosin XVA
MYOZ3 myozenin 3
NABP2 nucleic acid binding protein 2
NPPB natriuretic peptide B
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OTOF otoferlin
PCDH12 protocadherin 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLBD1 phospholipase B domain containing 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
PROX1 prospero homeobox 1
RAB3A RAB3A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGCC regulator of cell cycle
RNF39 ring finger protein 39
RUNDC3B RUN domain containing 3B
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
SPATA7 spermatogenesis associated 7
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TICAM1 toll-like receptor adaptor molecule 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
ZNF37BP zinc finger protein 37B, pseudogene
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747